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Trip from Rogersville, MO to Saint Charles, MO

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

4h 17m

Distance

221.9 mi

357 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$35

one way

EV Charging

Good

7 stations

Best Time to Leave

Save up to 40 min
4 AM
4h 4m ★
6 AM
4h 17m
8 AM
4h 44m
10 AM
4h 27m
12 PM
4h 24m
3 PM
4h 28m
5 PM
4h 42m
8 PM
4h 9m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly
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Downtown Rogersville, MO, MO

Rogersville, MO

Mark Stebnicki

city in and county seat of St. Charles County, Missouri, United States

Saint Charles, MO

Wikimedia Commons

Trip Overview

The drive from Rogersville, MO to Saint Charles, MO covers 221.9 miles and takes about 4h 17m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on I 44, I 270, MO 125 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 186.8 miles on I 44. At current regular gas prices, budget about $34.69 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

110.9 miles from Rogersville, MO

A natural place for your longest stop of the day , about 2h 10m into the drive .

Main Roads

Road Distance Duration
I 44 186.8 mi 3h 22m
I 270 12.6 mi 15m
MO 125 10.6 mi 18m
I 70 2.7 mi 3m
US 60 1.6 mi 1m
East Center Street 1.5 mi 2m
US Historic 66 1.3 mi 2m
South Fifth Street 1 mi 2m
Longest stretch: I 44 — 186.8 mi, about 3h 22m

Turn-by-Turn Driving Directions

Step-by-step road directions between Rogersville, MO and Saint Charles, MO.

1

Start on US 60 Business

1.5 mi · 2 min · East Center Street
2

Turn left

358 ft · 7 sec
3

Take the ramp

0.2 mi · 20 sec
4

Merge onto US 60

1.6 mi · 1 min · US 60
5

Take the exit

0.3 mi · 37 sec
6

Enter roundabout onto MO 125

36 ft · 0 sec · MO 125
7

Continue on MO 125

4.4 mi · 7 min · MO 125
8

Turn right onto MO 125

5.9 mi · 10 min · MO 125
9

Turn right onto US Historic 66; MO 125; MO OO

1.3 mi · 2 min · US Historic 66; MO 125; MO OO
10

Continue on MO 125

0.1 mi · 17 sec · MO 125
11

Turn slight right onto MO 125

360 ft · 8 sec · MO 125
12

Take the ramp

0.2 mi · 20 sec
Toward I 44 East: Rolla
13

Merge onto I 44

187 mi · 3 hr 22 min · I 44
14

Take the exit

0.2 mi · 18 sec
Exit 276 Toward I 270: Chicago, Memphis Use the slight right lane.
15

Keep slight left at fork

0.1 mi · 11 sec
Toward I 270 North: Chicago Use the slight left lane.
16

Continue on this road

0.5 mi · 52 sec · this road
Exit 276 Toward I 270 North: Chicago
17

Merge onto I 270

13 mi · 15 min · I 270
Use the straight lane.
18

Take the exit

1.0 mi · 1 min
Exit 20A Toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport Use the slight right lane.
19

Keep slight left at fork

0.1 mi · 11 sec
Toward I 70 West: Kansas City Use the slight left lane.
20

Continue on this road

0.6 mi · 57 sec · this road
Exit 20B Toward I 70 West: Kansas City
21

Merge onto I 70

2.7 mi · 3 min · I 70
22

Take the exit onto I 70 Business

0.2 mi · 17 sec · I 70 Business
Exit 229B Toward I 70 Business: Fifth Street Use the straight / slight right lanes.
23

Keep slight right at fork

231 ft · 5 sec
Toward I 70 Business: Fifth Street North, Bass Pro Drive, Ameristar Boulevard Use the right lane.
24

Turn slight right onto I 70 Business

1.0 mi · 2 min · South Fifth Street
Use the right lane.
25

Turn right onto Jefferson Street

0.2 mi · 44 sec · Jefferson Street
26

Turn left onto North Second Street

0.2 mi · 34 sec · North Second Street
27

Arrive at destination

North Second Street

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 110.9 miles from Rogersville, MO, or about 2h 10m into the drive.
The longest continuous stretch on this route runs about 186.8 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 49 miles or 1h 3m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 110.9 miles or 2h 10m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 27m

Traffic, exits, and arrival timing usually matter more near Saint Charles, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Rogersville, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Rogersville, MO

This is one driving day of about 221.9 miles and 4h 17m.

Your first comfortable stop window is around 49 miles from Rogersville, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 44 for about 186.8 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in and the county seat of Pulaski County, Missouri, United States

Mid-route town

Meal stop

Waynesville, MO

111 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Lebanon, MO

Fuel and coffee

A short stop after about 47 miles helps settle the day before fatigue starts building.

Bourbon, MO

Meal break

The midpoint is around 107.6 miles from Rogersville, MO, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Nearby Places

Restaurants, cafes, gas stations and more along your route.

Top Restaurant

The Wine Cafe

4.7 ★ ★ ★ ★ ★

St Charles, Missouri

Near the end, right off the route

0.5 mi from route ~1 min detour $10 to $20 mile 221.9

Hours: 11 am–8 pm

+16364108002

Visit website

Top Coffee Stop

Cafe Amalia

4.6 ★ ★ ★ ★ ★

Kirkwood, Missouri

Near the end, short detour

2.2 mi from route ~6 min detour $20 to $30 mile 206

Hours: 8 am–3 pm

+13146982200

Visit website

The Wine Cafe

4.7 ★ ★ ★ ★ ★

Near the end, right off the route

0.5 mi from route ~1 min detour $10 to $20 mile 221.9

St Charles, Missouri

Hours: 11 am–8 pm

+16364108002

Visit website

Cafe Amalia

4.6 ★ ★ ★ ★ ★

Near the end, short detour

2.2 mi from route ~6 min detour $20 to $30 mile 206

Kirkwood, Missouri

Hours: 8 am–3 pm

+13146982200

Visit website

Tesla Supercharger

4.3 ★ ★ ★ ★ ☆

Around the midpoint, right off the route

0.4 mi from route ~1 min detour mile 110.9

Rolla, Missouri

Hours: Open 24 hours

Visit website

Blink Charging Station

2.4 ★ ★ ☆ ☆ ☆

Around the midpoint, short detour

1.8 mi from route ~5 min detour mile 110.9

Rolla, Missouri

Hours: Open 24 hours

Visit website

Blink Charging Station

5.0 ★ ★ ★ ★ ★

Near the start, ~11 min detour

4.4 mi from route ~11 min detour mile 31.7

Marshfield, Missouri

Hours: Open 24 hours

+18889982546

Visit website

EV Connect Charging Station

3.0 ★ ★ ★ ☆ ☆

Near the start, ~11 min detour

4.3 mi from route ~11 min detour mile 31.7

Marshfield, Missouri

Hours: Open 24 hours

+18668167584

Visit website

EV Connect Charging Station

1.0 ★ ☆ ☆ ☆ ☆

Near the start, ~9 min detour

3.8 mi from route ~9 min detour mile 31.7

Marshfield, Missouri

Hours: Open 24 hours

+18668167584

Visit website

Blink Charging Station

Near the start, ~10 min detour

3.9 mi from route ~10 min detour mile 31.7

Marshfield, Missouri

Hours: Open 24 hours

+18889982546

Visit website

Blink Charging Station

Near the start, ~11 min detour

4.3 mi from route ~11 min detour mile 31.7

Marshfield, Missouri

Hours: Open 24 hours

+18889982546

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 20

5 decision points cluster between mile 202.4 and 220.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

8
202.4 mi into trip | ~3h 50m in

Take the exit toward I 270: Chicago, Memphis

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 276 Toward I 270: Chicago, Memphis
8
202.6 mi into trip | ~3h 50m in

Keep slight left at fork toward I 270 North: Chicago

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight left lane. Toward I 270 North: Chicago
8
215.8 mi into trip | ~4h 7m in

Take the exit toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 20A Toward I 70: Kansas City, Saint Louis, Saint Lo...
7
216.8 mi into trip | ~4h 8m in

Keep slight left at fork toward I 70 West: Kansas City

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight left lane. Toward I 70 West: Kansas City
9
220.4 mi into trip | ~4h 13m in

Keep slight right at fork toward I 70 Business: Fifth Street North, Bass Pro Drive, Ameristar Boulevard

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the right lane. Toward I 70 Business: Fifth Street North, Bass...

Fuel & Cost

Regular Gas

$34.69 one way

$69.38 round trip

$3.97/gal 25.4 MPG avg 78 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $38.09 $76.18
premium $4.89 $42.70 $85.41
diesel $5.61 $48.99 $97.99

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$35

Meals

$25–$50

Total

$60–$85

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 77.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $23 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 66.6 0 $23.30 $10.65
Efficient EV 55.5 0 $19.42 $8.88
EV Truck/SUV 88.8 1 $31.07 $14.20

Gas CO2

78 kg

EV CO2

26 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Rogersville, MO

Afternoon in Rogersville on Saturday

Local time

12:39 PM

CDT

Current temp

54°F

Unavailable

Live forecast

Destination

Saint Charles, MO

Afternoon in Saint Charles on Saturday

Local time

12:39 PM

CDT

Current temp

57°F

Unavailable

Live forecast

76°F

Waynesville, MO

111 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

3 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 17m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Gateway Arch National Park

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

14 mi from route ~36 min detour $19 near mile 200.3
View on nps.gov
Wilson's Creek National Battlefield

Wilson's Creek National Battlefield

National Battlefield

Wilson's Creek was the first major Civil War battle fought west of the Mississippi River, and where the first Union general was killed in action. The costly Southern victory on August 10, 1861, focuse...

17 mi from route ~42 min detour Free near mile 7.4
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

This is a 4h 17m highway drive covering 221.9 miles, with most of the trip on I 44 and I 270. The longest continuous stretch is about 186.8 miles on I 44.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 27 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 44 is the longest continuous segment at about 186.8 miles.

How Hard Is This Drive?

10/10

This is a straightforward highway drive that stays mostly on I 44 and I 270. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 202.4 miles in.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 20 significant decision points across 221.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 202.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 202.6 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 215.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Rogersville, MO to Saint Charles, MO, road signs begin pointing toward Memphis along the way.

Memphis

202.4 mi in | ~3h 50m

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 17m. Total distance: 221.9 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 17m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (97%). Some complex stretches to watch for.

Frequently Asked Questions

The drive from Rogersville, MO to Saint Charles, MO covers 221.9 miles and takes about 4h 17m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are I 44, I 270, MO 125. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 110.9 miles from Rogersville, MO. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $34.69 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

This is a demanding drive. With 20 significant decision points across 221.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

The main spots that need attention: at 202.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 202.6 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 215.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

On the drive from Rogersville, MO to Saint Charles, MO, road signs begin pointing toward Memphis along the way.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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