The drive from Saint Charles, MO to Monroe City, MO covers 115.2 miles and takes about 2h 23m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Avenue of the Saints, I 70, Chicago-Kansas City Expressway for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 73.3 miles on Avenue of the Saints.
At current regular gas prices, budget about $18.01 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
57.6 miles from Saint Charles, MO
A natural place for your longest stop of the day
, about 1h 12m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 23m. Total distance: 115.2 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 23m drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a 2h 23m drive with frequent turns across 115.2 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 19 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Avenue of the Saints is the longest continuous segment at about 73.3 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 2.3 miles in near I 70.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 115.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 2.3 miles (I 70): Merge point - match speed before joining. Lane positioning matters here; at 19.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 20.1 miles (US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here.
Critical Maneuvers
5 of 14 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
2.3 mi into trip|~5m in|I 70
Merge onto I 70
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
7
19.7 mi into trip|~27m in
Take the exit toward US 61 North: Hannibal
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 210B
Toward US 61 North: Hannibal
5
20.1 mi into trip|~27m in|US 61 / Avenue of the Saints
Merge onto US 61 / Avenue of the Saints
Merge point - match speed before joining. Lane positioning matters here
Use the right lane.
6
96.2 mi into trip|~2h in
Take the ramp toward US 36 West, MO 110 West: Monroe City
Multiple destination signs - pick the right one
Toward US 36 West, MO 110 West: Monroe City
5
113.1 mi into trip|~2h 19m in|US 24; US 36 Business
Take the exit onto US 24; US 36 Business toward US 24 West, US 36 Business, MO Z: Monroe City, Paris, Moberly
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 24 West, US 36 Business, MO Z: Monroe...
Main Roads
Road
Distance
Duration
Avenue of the Saints
73.3 mi
1h 26m
I 70
17.5 mi
21m
Chicago-Kansas City Expressway
10.7 mi
12m
V.F.W. Memorial Highway
5.8 mi
6m
Veterans Road
2.2 mi
3m
First Capitol Drive
1.8 mi
4m
5th Street
1.1 mi
1m
US 24
0.8 mi
1m
Longest stretch:
Avenue of the Saints
— 73.3 mi, about 1h 26m
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles, MO and Monroe City, MO.
1
Start on North Second Street
0.3 mi·1 min·North Second Street
2
Turn right onto First Capitol Drive
0.9 mi·2 min·First Capitol Drive
3
Turn left onto I 70 Business; MO 94
0.9 mi·2 min·First Capitol Drive
4
Take the ramp
0.2 mi·14 sec
Toward I 70 West
5
Merge onto I 70
17 mi·21 min·I 70
Use the straight / slight right lanes.
6
Take the exit
0.4 mi·47 sec
Exit 210BToward US 61 North: HannibalUse the slight right lane.
7
Merge onto US 61
73 mi·1 hr 26 min·Avenue of the Saints
Use the right lane.
8
Take the exit
249 ft·14 sec
9
Turn left onto Paris Gravel Road
0.5 mi·1 min·Paris Gravel Road
10
Keep slight right at fork onto County Road 422
279 ft·8 sec·County Road 422
11
Turn right onto Veterans Road
2.2 mi·3 min·Veterans Road
12
Take the ramp
0.2 mi·16 sec
Toward US 36 West, MO 110 West: Monroe City
13
Merge onto US 36; MO 110
5.8 mi·6 min·V.F.W. Memorial Highway
14
Continue on US 24; US 36; MO 110
11 mi·12 min·Chicago-Kansas City Expressway
15
Take the exit onto US 24; US 36 Business
0.3 mi·56 sec·US 24; US 36 Business
Toward US 24 West, US 36 Business, MO Z: Monroe City, Paris, Moberly
16
Turn left onto US 24; US 36 Business; MO Z
0.4 mi·38 sec·US 24; US 36 Business; MO Z
17
Continue on US 24; US 36 Business
1.1 mi·1 min·5th Street
18
Turn left onto US 24
0.3 mi·23 sec·North Main Street
19
Arrive at destination
US 24
Trip Plan
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 57.6 miles from Saint Charles, MO, or about 1h 12m into the drive.
The longest continuous stretch on this route runs about 73.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 25 miles or 33m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 57.6 miles or 1h 12m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 57m
Traffic, exits, and arrival timing usually matter more near Monroe City, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Charles, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Charles, MO
This is one driving day of about 115.2 miles and 2h 23m.
Your first comfortable stop window is around 25 miles from Saint Charles, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Avenue of the Saints for about 73.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 57.6 mi from Saint Charles, MO
· 1h 12m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$18.01 one way
$36.02 round trip
$3.97/gal25.4 MPG avg40 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$19.77
$39.55
premium
$4.89
$22.17
$44.34
diesel
$5.61
$25.43
$50.87
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$18
Meals
$25–$50
Total
$43–$68
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 40.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
EV Charging Along Route
19 DC fast chargers
· Coverage: excellent
Tesla Supercharger
Lake St Louis, Missouri
Tesla
1 DCFC
ChargePoint Charging Station
St Peters, Missouri
ChargePoint
1 DCFC
Blink Charging Station
O'Fallon, Missouri
Blink
1 DCFC
EVXY Charging Station
Troy, Missouri
Other
1 DCFC
EVgo Charging Station
Wentzville, Missouri
EVgo
1 DCFC
Tesla Supercharger
Hannibal, Missouri
Tesla
1 DCFC
EVre Charging Station
Bowling Green, Missouri
Other
1 DCFC
Blink Charging Station
Wentzville, Missouri
Blink
1 DCFC
Other: 8
Blink: 4
ChargePoint: 3
Tesla: 2
EVgo: 2
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $12 in charging
· 0 stops
· 68% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
34.6
0
$12.10
$5.53
Efficient EV
28.8
0
$10.08
$4.61
EV Truck/SUV
46.1
0
$16.13
$7.37
Gas CO2
40 kg
EV CO2
13 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Saint Charles, MO
Late night
in Saint Charles on Friday
Local time
5:00 AM
CDT
Current temp
57°F
Unavailable
Live forecast
Destination
Monroe City, MO
Late night
in Monroe City on Friday
Local time
5:00 AM
CDT
Current temp
70°F
Unavailable
Live forecast
76°F
Troy, MO
58 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
13 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 23m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Saint Charles, MO to Monroe City, MO covers 115.2 miles and takes about 2h 23m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Avenue of the Saints, I 70, Chicago-Kansas City Expressway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 57.6 miles from Saint Charles, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $18.01 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a demanding drive. With 14 significant decision points across 115.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 2.3 miles (I 70): Merge point - match speed before joining. Lane positioning matters here; at 19.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 20.1 miles (US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here.
The route from Saint Charles, MO to Monroe City, MO does not surface many named destination signs beyond the main corridor.
How this page is built
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from
OSRM
over
OpenStreetMap.
Fuel cost uses
EIA
weekly regional averages.
EV charging comes from the
NREL Alternative Fuels
dataset.
National park proximity is from the
NPS API.
Pages are published only after passing our data-quality checks; our
methodology page
documents refresh cadence, editorial standards, and known limitations.
