Origin
Saint Charles, MO
Evening in Saint Charles on Thursday
Local time
5:26 PM
CDT
Current temp
57°F
Unavailable
Live forecast
Trip from Saint Charles, MO to Mound City, MO
Last recalculated Apr 16, 2026
Drive Time
6h 3m
Distance
320.5 mi
516 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$50
one way
EV Charging
Unknown
Best Time to Leave
4 AM
5h 51m
★
6 AM
6h 4m
8 AM
6h 29m
10 AM
6h 13m
12 PM
6h 10m
3 PM
6h 14m
5 PM
6h 28m
8 PM
5h 56m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Saint Charles, MO
Wikimedia Commons
Mound City, MO
Wikimedia Commons
Trip Overview
The drive from Saint Charles, MO to Mound City, MO covers 320.5 miles and takes about 6h 3m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on First Capitol Drive, I 70 West, Truman/Eisenhower Presidential Highway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $50.11 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
160.3 miles from Saint Charles, MO
A natural place for your longest stop of the day , about 3h 1m into the drive .
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 3m. Total distance: 320.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 3m drive, plan rest stops for pacing.
First-Time Driver
Mostly highway driving (0%). Straightforward navigation.
Scenic Drive
Turn-heavy local drive route profile.
Drive Character
Expect a 6h 3m drive with frequent turns across 320.5 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 20 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
First Capitol Drive is one of the defining roads on this drive.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Driving Effort
3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
The route itself is not hard, but at 6h 3m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Saint Charles, MO to Mound City, MO is straightforward, with well-signed roads and simple exits.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| First Capitol Drive | — | — |
| I 70 West | — | — |
| Truman/Eisenhower Presidential Highway | — | — |
| Clifton J | — | — |
| George Brett Super Highway | — | — |
| I 435 North | — | — |
| Lamar Hunt Memorial Highway | — | — |
| I435 N | — | — |
Some road-level metrics are being recalculated.
Longest stretch:
First Capitol Drive
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles, MO and Mound City, MO.
1
Start on North Second Street
0.3 mi
·
1 min
·
North Second Street
2
Turn right onto First Capitol Drive
0.9 mi
·
2 min
·
First Capitol Drive
3
Turn left onto First Capitol Drive
0.9 mi
·
2 min
·
First Capitol Drive
4
Take the ramp slight right toward I 70 West
0.2 mi
·
14 sec
·
I 70 West
5
Merge slight left
211 mi
·
3 hr 59 min
6
Continue on Truman/Eisenhower Presidential Highway
2.7 mi
·
3 min
·
Truman/Eisenhower Presidential Highway
7
Continue on Clifton J. Scott Memorial Highway
1.8 mi
·
2 min
·
Clifton J. Scott Memorial Highway
8
Continue on Truman/Eisenhower Presidential Highway
2.9 mi
·
3 min
·
Truman/Eisenhower Presidential Highway
9
Continue on George Brett Super Highway
0.8 mi
·
58 sec
·
George Brett Super Highway
10
Take the exit slight right toward I 435 North, US 24 East: Des Moines
1.1 mi
·
2 min
·
I 435 North, US 24 East: Des Moines
11
Merge slight left onto Lamar Hunt Memorial Highway
7.8 mi
·
9 min
·
Lamar Hunt Memorial Highway
12
Continue on I435 N
1.3 mi
·
1 min
·
I435 N
13
Continue straight
21 mi
·
22 min
14
Keep slight left to continue on I 29 North, US 71 North: Saint Joseph
37 mi
·
40 min
·
I 29 North, US 71 North: Saint Joseph
15
Continue straight
30 mi
·
32 min
16
Take the exit slight right toward MO 118: Mound City
0.2 mi
·
20 sec
·
MO 118: Mound City
17
Turn right
0.2 mi
·
21 sec
18
Turn right onto State Street
0.2 mi
·
49 sec
·
State Street
19
Turn left
98 ft
·
7 sec
20
Arrive at your destination
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 160.3 miles from Saint Charles, MO, or about 3h 1m into the drive.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 71 miles or 1h 20m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 160.3 miles or 3h 1m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 58m
Traffic, exits, and arrival timing usually matter more near Mound City, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Charles, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Charles, MO
This is one driving day of about 320.5 miles and 6h 3m.
Your first comfortable stop window is around 71 miles from Saint Charles, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 160.3 mi from Saint Charles, MO · 3h 1m into the drive
Mid-route town
Meal stop
160 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 71 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 160.3 miles from Saint Charles, MO, which is a good place for a longer meal and fuel stop.
Arriving in Mound City, MO
The final approach into Mound City, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Mound City, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$50.11 one way
$100.21 round trip
$3.97/gal
25.4 MPG avg
112 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $55.01 | $110.03 |
| premium | $4.89 | $61.68 | $123.35 |
| diesel | $5.61 | $70.76 | $141.52 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$50
Meals
$25–$50
Total
$75–$100
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 112.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $34 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 96.1 | 1 | $33.65 | $15.38 |
| Efficient EV | 80.1 | 0 | $28.04 | $12.82 |
| EV Truck/SUV | 128.2 | 1 | $44.87 | $20.51 |
Gas CO2
112 kg
EV CO2
37 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Mound City, MO
Evening in Mound City on Thursday
Local time
5:26 PM
CDT
Current temp
75°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
18 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 3m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Saint Charles, MO to Mound City, MO covers 320.5 miles and takes about 6h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are First Capitol Drive, I 70 West, Truman/Eisenhower Presidential Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 160.3 miles from Saint Charles, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $50.11 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 6h 3m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from Saint Charles, MO to Mound City, MO is straightforward, with well-signed roads and simple exits.
The route from Saint Charles, MO to Mound City, MO does not surface many named destination signs beyond the main corridor.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore More
Continue From Mound City, MO
More trips to Mound City, MO
Explore more options from Saint Charles, MO or browse trips ending in Mound City, MO.
Looking for more statewide routes? Browse MO road trips.
Explore maps for Saint Charles, MO or Mound City, MO on MapSof.net.