Origin
Saint Charles, MO
Afternoon in Saint Charles on Saturday
Local time
2:34 PM
CDT
Current temp
57°F
Unavailable
Live forecast
Trip from Saint Charles, MO to Doniphan, MO
Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
3h 48m
Distance
189.1 mi
304 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$30
one way
EV Charging
Unknown
Best Time to Leave
4 AM
3h 36m
★
6 AM
3h 48m
8 AM
4h 14m
10 AM
3h 57m
12 PM
3h 55m
3 PM
3h 59m
5 PM
4h 13m
8 PM
3h 41m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Saint Charles, MO
Wikimedia Commons
Doniphan, MO
Wikimedia Commons
Trip Overview
The drive from Saint Charles, MO to Doniphan, MO covers 189.1 miles and takes about 3h 48m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 67, I 270, Police Officer Steven Jarvis Memorial Highway for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 123.1 miles on US 67. At current regular gas prices, budget about $29.56 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
94.6 miles from Saint Charles, MO
A natural place for your longest stop of the day , about 1h 53m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| US 67 | 123.1 mi | 2h 21m |
| I 270 | 19 mi | 23m |
| Police Officer Steven Jarvis Memorial Highway | 18.3 mi | 19m |
| US 160 | 18.2 mi | 27m |
| I 70 | 2.7 mi | 3m |
| Officer Thomas G. Smith, Jr. Memorial Highway | 1.8 mi | 2m |
| Rosa Parks Highway | 1.5 mi | 1m |
| South Fifth Street | 1.1 mi | 2m |
Longest stretch:
US 67
— 123.1 mi, about 2h 21m
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles, MO and Doniphan, MO.
1
Start on North Second Street
0.2 mi
·
38 sec
·
North Second Street
2
Turn right onto Jefferson Street
0.2 mi
·
44 sec
·
Jefferson Street
3
Turn left onto MO 94
1.1 mi
·
2 min
·
South Fifth Street
Use the straight / right lanes.
4
Take the ramp
0.2 mi
·
14 sec
Toward I 70 East
Use the left / straight lanes.
5
Merge onto I 70
2.7 mi
·
3 min
·
I 70
6
Take the exit
0.2 mi
·
12 sec
Exit 232
Toward I 270: Chicago, Memphis
Use the slight right lane.
7
Keep slight right at fork
0.4 mi
·
33 sec
Toward I 270 South: Memphis
Use the slight right lane.
8
Continue on this road
0.1 mi
·
10 sec
·
this road
Exit 232
Toward I 270 South: Memphis
9
Merge onto I 270
19 mi
·
23 min
·
I 270
Use the straight lane.
10
Take the exit
0.4 mi
·
27 sec
Exit 1A
Toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
Use the straight / slight right lanes.
11
Keep slight right at fork
0.4 mi
·
43 sec
Toward I 55 South: Memphis
12
Merge onto I 55
1.5 mi
·
1 min
·
Rosa Parks Highway
13
Continue on I 55
1.8 mi
·
2 min
·
Officer Thomas G. Smith, Jr. Memorial Highway
14
Continue on I 55
18 mi
·
19 min
·
Police Officer Steven Jarvis Memorial Highway
Use the straight / slight right lanes.
15
Take the exit
0.2 mi
·
19 sec
Exit 174B
Toward US 67 South: Farmington, Poplar Bluff
16
Keep slight left at fork
0.1 mi
·
17 sec
17
Enter roundabout onto US 67
30 ft
·
0 sec
·
US 67
18
Continue on US 67
113 mi
·
2 hr 9 min
·
US 67
19
Take the exit onto US 67
10 mi
·
11 min
·
US 67
Toward US 67 South: Corning, Arkansas
20
Take the exit
0.3 mi
·
45 sec
21
Continue on US 160
18 mi
·
27 min
·
US 160
22
Turn left onto MO 142
0.7 mi
·
1 min
·
Walnut Street
23
Turn left onto Plum Street
169 ft
·
7 sec
·
Plum Street
24
Arrive at destination
Plum Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 94.6 miles from Saint Charles, MO, or about 1h 53m into the drive.
The longest continuous stretch on this route runs about 123.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 42 miles or 52m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 94.6 miles or 1h 53m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 2m
Traffic, exits, and arrival timing usually matter more near Doniphan, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Charles, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Charles, MO
This is one driving day of about 189.1 miles and 3h 48m.
Your first comfortable stop window is around 42 miles from Saint Charles, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 67 for about 123.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
95 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 42 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 94.6 miles from Saint Charles, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 67 if your tank is already low. That segment runs about 123.1 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 175 decision points cluster between mile 0.4 and 46.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
0.4 mi into trip
|
~1m in
|
MO 94 / South Fifth Street
Turn left onto MO 94 / South Fifth Street
Lane positioning matters here
Use the straight / right lanes.
8
4.3 mi into trip
|
~7m in
Take the exit toward I 270: Chicago, Memphis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 232
Toward I 270: Chicago, Memphis
7
4.5 mi into trip
|
~8m in
Keep slight right at fork toward I 270 South: Memphis
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 270 South: Memphis
8
24.1 mi into trip
|
~32m in
Take the exit toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 1A
Toward I 55, US 61, US 67: Saint Louis, Memphis...
6
46.5 mi into trip
|
~57m in
Take the exit toward US 67 South: Farmington, Poplar Bluff
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 174B
Toward US 67 South: Farmington, Poplar Bluff
Fuel & Cost
Regular Gas
$29.56 one way
$59.13 round trip
$3.97/gal
25.4 MPG avg
66 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $32.46 | $64.92 |
| premium | $4.89 | $36.39 | $72.78 |
| diesel | $5.61 | $41.75 | $83.50 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 66.2 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $20 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 56.7 | 0 | $19.86 | $9.08 |
| Efficient EV | 47.3 | 0 | $16.55 | $7.56 |
| EV Truck/SUV | 75.6 | 0 | $26.47 | $12.10 |
Gas CO2
66 kg
EV CO2
22 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Doniphan, MO
Afternoon in Doniphan on Saturday
Local time
2:34 PM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
20 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 48m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
13 mi from route
~33 min detour
$19
near mile 26.1
View on nps.gov
Ste. Geneviève National Historical Park
National Historical Park
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
25 mi from route
~62 min detour
Free
near mile 58.7
View on nps.gov
Park data from the National Park Service API. Alerts update every 2 hours.
What kind of drive is this?
189.1 mi in 3h 48m, mostly highway — 123.1 mi of that is on US 67.
86% highway — fuel and pacing are the main things to plan.
24 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 123.1 mi on US 67.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on US 67 and I 270. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.4 miles in near MO 94 / South Fifth Street.
Driving Effort
9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 189.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 4.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Elevation Profile
Mostly flat terrain
979 ft
378 ft
Total Climb
896 ft
Total Descent
989 ft
Highest Point
979 ft
~81.1 mi in
Elevation Range
601 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Saint Charles, MO and Doniphan, MO, road signs point toward Memphis, Poplar Bluff and Arkansas.
Memphis
24.1 mi in
|
~32m
Poplar Bluff
46.5 mi in
|
~57m
Arkansas
159.5 mi in
|
~3h 7m
|
via US 67
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 48m. Total distance: 189.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 48m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (86%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 123.1 miles on US 67. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Doniphan, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 4.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Yes — Gateway Arch National Park and Ste. Geneviève National Historical Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.8 hours each way, an in-and-out day trip would put you behind the wheel for 7.6 hours — manageable with a long break at Doniphan, MO, but most travelers stay overnight.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and NPS for national parks. See our methodology for refresh cadence and limitations.
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