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Trip from Saint Joseph, MO to Sainte Genevieve County, MO

Last recalculated Apr 16, 2026

Drive Time

6h 52m

Distance

358.5 mi

577 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$56

one way

EV Charging

Unknown

Best Time to Leave

Save up to 35 min
4 AM
6h 41m ★
6 AM
6h 53m
8 AM
7h 16m
10 AM
7h 1m
12 PM
6h 58m
3 PM
7h 2m
5 PM
7h 15m
8 PM
6h 46m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in and county seat of Buchanan County, Missouri, United States

Saint Joseph, MO

Wikimedia Commons

Downtown Sainte Genevieve County, MO, MO

Sainte Genevieve County, MO

Thomas Parker

Trip Overview

The drive from Saint Joseph, MO to Sainte Genevieve County, MO covers 358.5 miles and takes about 6h 52m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Police Officer Steven Jarvis Memorial Highway for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 135.3 miles on Dwight D. Eisenhower Highway. At current regular gas prices, budget about $56.05 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

179.2 miles from Saint Joseph, MO

A natural place for your longest stop of the day , about 3h 16m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 6h 52m. Total distance: 358.5 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

6h 52m drive, plan rest stops for pacing.

Scenic Drive

Turn-heavy local drive route profile.

Drive Character

Expect a 6h 52m drive with frequent turns across 358.5 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 42 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D. Eisenhower Highway is the longest continuous segment at about 135.3 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 35.2 miles in near I 435.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 28 significant decision points across 358.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 35.2 miles (I 435): Highway fork - watch signs carefully. Lane positioning matters here; at 63.2 miles (US 24): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 63.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Critical Maneuvers

5 of 28 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

8
35.2 mi into trip | ~39m in | I 435

Keep slight right at fork onto I 435 toward I 435 East: Saint Louis

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes. Exit 14 Toward I 435 East: Saint Louis
7
63.2 mi into trip | ~1h 10m in | US 24

Keep slight right at fork onto US 24 toward I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Exit 63 Toward I 70, US 24 West, US 40: Saint Louis, Ka...
7
63.5 mi into trip | ~1h 11m in

Keep slight left at fork toward I 70 East: Saint Louis

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes. Toward I 70 East: Saint Louis
8
291.2 mi into trip | ~5h 29m in

Take the exit toward I 270: Chicago, Memphis

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 25 Toward I 270: Chicago, Memphis
8
303.3 mi into trip | ~5h 45m in

Take the exit toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Exit 1A Toward I 55, US 61, US 67: Saint Louis, Memphis...

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Saint Joseph, MO and Sainte Genevieve County, MO, road signs point toward Kansas City, Sports Complex and Memphis.

Kansas City

63.2 mi in | ~1h 10m | via US 24

Sports Complex

63.2 mi in | ~1h 10m | via US 24

Memphis

291.2 mi in | ~5h 29m

Main Roads

Road Distance Duration
Dwight D. Eisenhower Highway 135.3 mi 2h 34m
U.S. Submarine Veterans' Memorial Highway 54.4 mi 58m
Police Officer Steven Jarvis Memorial Highway 42.6 mi 45m
I 29 28.4 mi 30m
I 435 28 mi 30m
Avenue of the Saints 25.1 mi 30m
I 270 11.5 mi 14m
MO 32 6.7 mi 10m
Longest stretch: Dwight D. Eisenhower Highway — 135.3 mi, about 2h 34m

Turn-by-Turn Driving Directions

Step-by-step road directions between Saint Joseph, MO and Sainte Genevieve County, MO.

1

Start on Walter Welsh Avenue

417 ft · 8 sec · Walter Welsh Avenue
2

Turn right onto North 12th Street

297 ft · 10 sec · North 12th Street
3

Turn right onto Francis Street

0.2 mi · 37 sec · Francis Street
4

Turn left onto I 29 Business

1.2 mi · 2 min · North 9th Street
5

Take the ramp

0.1 mi · 15 sec
6

Merge onto US 36

0.2 mi · 19 sec · US 36
7

Take the exit

0.2 mi · 21 sec
Toward I 229 South, US 59 South: Kansas City
8

Merge onto I 229; US 59

4.5 mi · 4 min · I 229; US 59
9

Keep slight right at fork

0.3 mi · 29 sec
Toward I 29 South, US 71 South: Kansas City
10

Merge onto I 29; US 71

26 mi · 27 min · I 29; US 71
11

Merge onto I 29; I 435; US 71

2.2 mi · 2 min · I 29; I 435; US 71
Use the straight / slight right lanes.
12

Keep slight right at fork onto I 435

28 mi · 30 min · I 435
Exit 14 Toward I 435 East: Saint Louis Use the straight / slight right lanes.
13

Keep slight right at fork onto US 24

0.3 mi · 23 sec · US 24
Exit 63 Toward I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
14

Keep slight left at fork

1.2 mi · 1 min
Toward I 70 East: Saint Louis Use the straight / slight right lanes.
15

Keep slight left at fork

469 ft · 11 sec
Toward I 70 East: Saint Louis Use the slight left / straight lanes.
16

Merge onto I 70

0.4 mi · 29 sec · George Brett Super Highway
17

Continue on I 70

2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
18

Continue on I 70

1.8 mi · 2 min · Clifton J. Scott Memorial Highway
Use the straight / slight right lanes.
19

Continue on I 70

2.6 mi · 3 min · Truman/Eisenhower Presidential Highway
20

Continue on I 70

53 mi · 56 min · Dwight D. Eisenhower Highway
21

Continue on I 70; US 40

32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
22

Keep slight left at fork onto I 70

22 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
23

Continue on I 70; US 40

1.8 mi · 2 min · Dwight D. Eisenhower Highway
24

Continue on I 70; US 40

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
25

Continue on I 70; US 40

1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
26

Continue on I 70; US 40

81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway
27

Take the exit onto US 40

0.3 mi · 33 sec · US 40
Exit 210A Toward I 64 East, US 40 East, US 61 South: Chesterfield
28

Merge onto I 64; US 40; US 61

25 mi · 30 min · Avenue of the Saints
Use the straight / slight left lanes.
29

Take the exit

0.3 mi · 38 sec
Exit 25 Toward I 270: Chicago, Memphis Use the slight right lane.
30

Keep slight right at fork

0.3 mi · 31 sec
Toward I 270 South: Memphis Use the slight right lane.
31

Merge onto I 270

11 mi · 14 min · I 270
Use the straight lane.
32

Take the exit

0.4 mi · 27 sec
Exit 1A Toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road Use the straight / slight right lanes.
33

Keep slight right at fork

0.4 mi · 43 sec
Toward I 55 South: Memphis
34

Merge onto I 55

1.5 mi · 1 min · Rosa Parks Highway
35

Continue on I 55

1.8 mi · 2 min · Officer Thomas G. Smith, Jr. Memorial Highway
36

Continue on I 55

43 mi · 45 min · Police Officer Steven Jarvis Memorial Highway
Use the straight / slight right lanes.
37

Take the exit

0.2 mi · 16 sec
Exit 150 Toward MO 32, MO A, MO B: Sainte Genevieve, Farmington
38

Turn sharp right onto MO 32

6.7 mi · 10 min · MO 32
39

Turn left onto River Aux Vases Church Road

0.2 mi · 51 sec · River Aux Vases Church Road
40

Turn left onto River Aux Vases Church Road

0.7 mi · 2 min · River Aux Vases Church Road
41

Turn left

0.6 mi · 2 min
42

Arrive at destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 179.2 miles from Saint Joseph, MO, or about 3h 16m into the drive.
The longest continuous stretch on this route runs about 135.3 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 79 miles or 1h 28m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 179.2 miles or 3h 16m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 39m

Traffic, exits, and arrival timing usually matter more near Sainte Genevieve County, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Saint Joseph, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Saint Joseph, MO

This is one driving day of about 358.5 miles and 6h 52m.

Your first comfortable stop window is around 79 miles from Saint Joseph, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D. Eisenhower Highway for about 135.3 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 179.2 mi from Saint Joseph, MO · 3h 16m into the drive

Downtown O'Fallon, MO, MO

Mid-route town

Meal stop

O'Fallon, MO

179 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Blue Springs, MO

Fuel and coffee

A short stop after about 79 miles helps settle the day before fatigue starts building.

Columbia, MO

Meal break

The midpoint is around 179.2 miles from Saint Joseph, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 135.3 miles.

Arriving in Sainte Genevieve County, MO

The final approach into Sainte Genevieve County, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Sainte Genevieve County, MO.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$56.05 one way

$112.09 round trip

$3.97/gal 25.4 MPG avg 125 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $61.54 $123.08
premium $4.89 $68.99 $137.98
diesel $5.61 $79.15 $158.30

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$56

Meals

$25–$50

Total

$81–$106

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 125.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $38 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 107.6 1 $37.64 $17.21
Efficient EV 89.6 1 $31.37 $14.34
EV Truck/SUV 143.4 1 $50.19 $22.94

Gas CO2

125 kg

EV CO2

42 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Saint Joseph, MO

Afternoon in Saint Joseph on Thursday

Local time

4:03 PM

CDT

Current temp

74°F

Unavailable

Live forecast

Destination

Sainte Genevieve County, MO

Afternoon in Sainte Genevieve County on Thursday

Local time

4:03 PM

CDT

Current temp

45°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

29 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 52m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Saint Joseph, MO to Sainte Genevieve County, MO covers 358.5 miles and takes about 6h 52m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Police Officer Steven Jarvis Memorial Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 179.2 miles from Saint Joseph, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $56.05 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 28 significant decision points across 358.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 35.2 miles (I 435): Highway fork - watch signs carefully. Lane positioning matters here; at 63.2 miles (US 24): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 63.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Between Saint Joseph, MO and Sainte Genevieve County, MO, road signs point toward Kansas City, Sports Complex and Memphis.

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