Origin
Saint Joseph, MO
Afternoon in Saint Joseph on Thursday
Local time
4:03 PM
CDT
Current temp
74°F
Unavailable
Last recalculated Apr 16, 2026
Drive Time
6h 52m
Distance
358.5 mi
577 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$56
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Saint Joseph, MO
Wikimedia Commons
Sainte Genevieve County, MO
Thomas Parker
The drive from Saint Joseph, MO to Sainte Genevieve County, MO covers 358.5 miles and takes about 6h 52m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Police Officer Steven Jarvis Memorial Highway for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 135.3 miles on Dwight D. Eisenhower Highway. At current regular gas prices, budget about $56.05 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
179.2 miles from Saint Joseph, MO
A natural place for your longest stop of the day , about 3h 16m into the drive .
Weekend Trip
Doable as a same-day drive at 6h 52m. Total distance: 358.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 52m drive, plan rest stops for pacing.
Scenic Drive
Turn-heavy local drive route profile.
Expect a 6h 52m drive with frequent turns across 358.5 miles of local and secondary roads.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 35.2 miles in near I 435.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 28 significant decision points across 358.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 35.2 miles (I 435): Highway fork - watch signs carefully. Lane positioning matters here; at 63.2 miles (US 24): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 63.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight right at fork onto I 435 toward I 435 East: Saint Louis
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork onto US 24 toward I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight left at fork toward I 70 East: Saint Louis
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward I 270: Chicago, Memphis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Saint Joseph, MO and Sainte Genevieve County, MO, road signs point toward Kansas City, Sports Complex and Memphis.
Kansas City
Sports Complex
Memphis
| Road | Distance | Duration |
|---|---|---|
| Dwight D. Eisenhower Highway | 135.3 mi | 2h 34m |
| U.S. Submarine Veterans' Memorial Highway | 54.4 mi | 58m |
| Police Officer Steven Jarvis Memorial Highway | 42.6 mi | 45m |
| I 29 | 28.4 mi | 30m |
| I 435 | 28 mi | 30m |
| Avenue of the Saints | 25.1 mi | 30m |
| I 270 | 11.5 mi | 14m |
| MO 32 | 6.7 mi | 10m |
Step-by-step road directions between Saint Joseph, MO and Sainte Genevieve County, MO.
Start on Walter Welsh Avenue
Turn right onto North 12th Street
Turn right onto Francis Street
Turn left onto I 29 Business
Take the ramp
Merge onto US 36
Take the exit
Merge onto I 229; US 59
Keep slight right at fork
Merge onto I 29; US 71
Merge onto I 29; I 435; US 71
Keep slight right at fork onto I 435
Keep slight right at fork onto US 24
Keep slight left at fork
Keep slight left at fork
Merge onto I 70
Continue on I 70
Continue on I 70
Continue on I 70
Continue on I 70
Continue on I 70; US 40
Keep slight left at fork onto I 70
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Take the exit onto US 40
Merge onto I 64; US 40; US 61
Take the exit
Keep slight right at fork
Merge onto I 270
Take the exit
Keep slight right at fork
Merge onto I 55
Continue on I 55
Continue on I 55
Take the exit
Turn sharp right onto MO 32
Turn left onto River Aux Vases Church Road
Turn left onto River Aux Vases Church Road
Turn left
Arrive at destination
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 79 miles or 1h 28m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 179.2 miles or 3h 16m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 39m
Traffic, exits, and arrival timing usually matter more near Sainte Genevieve County, MO than in the middle of the route.
Open the route before leaving Saint Joseph, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Joseph, MO
This is one driving day of about 358.5 miles and 6h 52m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 179.2 mi from Saint Joseph, MO · 3h 16m into the drive
Mid-route town
Meal stop
179 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 79 miles helps settle the day before fatigue starts building.
The midpoint is around 179.2 miles from Saint Joseph, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 135.3 miles.
The final approach into Sainte Genevieve County, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Sainte Genevieve County, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$56.05 one way
$112.09 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $61.54 | $123.08 |
| premium | $4.89 | $68.99 | $137.98 |
| diesel | $5.61 | $79.15 | $158.30 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$56
Meals
$25–$50
Total
$81–$106
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 125.4 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $38 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 107.6 | 1 | $37.64 | $17.21 |
| Efficient EV | 89.6 | 1 | $31.37 | $14.34 |
| EV Truck/SUV | 143.4 | 1 | $50.19 | $22.94 |
Gas CO2
125 kg
EV CO2
42 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Saint Joseph on Thursday
Local time
4:03 PM
CDT
Current temp
74°F
Unavailable
Destination
Afternoon in Sainte Genevieve County on Thursday
Local time
4:03 PM
CDT
Current temp
45°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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