Saint Joseph, MO Road Trips

Sitting in the Midwest, Saint Joseph, MO is a local road trip base with 41 trip routes mapped and ready to explore. Routes from here tend to cover serious ground — the average trip runs 229 miles, so plan for multi-day adventures. Routes from Saint Joseph, MO spread mainly east and south, covering a wide geographic range.

Photo: Andrés Oliver Joya Zapata

Trip Routes

41

Longest Drive

486.6 mi

Caruthersville, MO

Quickest Drive

20m

Taos, MO

Plan Around Saint Joseph, MO

Popular Incoming Routes

Useful if Saint Joseph, MO is the arrival point and you want the strongest routes into the city first.

Bethany, MO to Saint Joseph, MO 438.9 mi · 8h 56m Scott City, MO to Saint Joseph, MO 412.4 mi · 7h 46m Doniphan, MO to Saint Joseph, MO 406.7 mi · 8h 8m Perryville, MO to Saint Joseph, MO 371.9 mi · 7h 5m

Continue From Saint Joseph, MO

Good next legs if this city is only one stop in a longer road trip.

Saint Joseph, MO to Caruthersville, MO 486.6 mi · 9h 6m Saint Joseph, MO to Perryville, MO 371.7 mi · 7h 3m Saint Joseph, MO to De Soto, MO 330.6 mi · 6h 23m Saint Joseph, MO to St. Louis, MO 306.3 mi · 4h 37m

Trips from Saint Joseph, MO

Saint Joseph, MO to Caruthersville, MO

486.6 mi 9h 6m

Saint Joseph, MO to Perryville, MO

371.7 mi 7h 3m

Saint Joseph, MO to De Soto, MO

330.6 mi 6h 23m

Saint Joseph, MO to St. Louis, MO

306.3 mi 4h 37m

Saint Joseph, MO to Florissant, MO

298.2 mi 4h 30m

Saint Joseph, MO to Brentwood, MO

298 mi 5h 40m

Saint Joseph, MO to Ladue, MO

296.3 mi 5h 40m

Saint Joseph, MO to Cuba, MO

290 mi 5h 34m

Saint Joseph, MO to Billings, MO

235.9 mi 4h 41m

Saint Joseph, MO to Camdenton, MO

205.9 mi 4h 19m

Saint Joseph, MO to Lake Lotawana, MO

85.4 mi 1h 47m

Saint Joseph, MO to Tarkio, MO

64.7 mi 1h 20m

Saint Joseph, MO to Kansas City, MO

53.8 mi 1h 3m

Saint Joseph, MO to Claycomo, MO

53.7 mi 1h

Saint Joseph, MO to Pleasant Valley, MO

53.6 mi 1h 1m

Driving from Saint Joseph, MO

Expect an average of 229 miles and about 4h 15m behind the wheel when leaving Saint Joseph, MO. There is a healthy spread of short hops, medium drives, and longer road trips to pick from. The longest mapped route runs 487 miles (9h 6m), while the shortest is just 54 miles.

Popular Destinations

The most popular drives from Saint Joseph, MO include Caruthersville, MO (486.6 mi, 9h 6m), Perryville, MO (371.7 mi, 7h 3m), De Soto, MO (330.6 mi, 6h 23m), St. Louis, MO (306.3 mi, 4h 37m), and Florissant, MO (298.2 mi, 4h 30m). Most destinations stay within the same state, perfect for exploring the local region thoroughly.

Planning & Costs

Regular gas in MO currently averages around $3.77 per gallon. For the typical 229-mile trip from Saint Joseph, MO, budget about $34 in fuel one way, assuming 25 MPG. Longer hauls and premium fuel will cost proportionally more.

Routes tend to go east, so afternoon departures put the sun at your back on the return leg. Most trips take a half-day, so a morning start gets you there in time for lunch or an afternoon of exploring.

Frequently Asked Questions

There are 15 mapped routes leaving Saint Joseph, MO and 26 routes heading into Saint Joseph, MO, covering 41 total connections. Distances range from 54 to 487 miles.

The longest mapped route from Saint Joseph, MO covers 487 miles and takes approximately 9h 6m. Shorter options start at just 54 miles.

The average route from Saint Joseph, MO runs about 229 miles with a drive time of roughly 4h 15m. This includes both short day trips and longer multi-day drives.

At current gas prices (about $3.77/gallon for regular), the average 229-mile trip from Saint Joseph, MO costs roughly $34 in fuel one way, based on 25 MPG. Your actual cost depends on your vehicle's efficiency.

The most popular road trip destinations from Saint Joseph, MO include Caruthersville, MO, Perryville, MO, De Soto, MO and St. Louis, MO. Each route page has detailed drive times, fuel estimates, stop suggestions, and turn-by-turn directions.