Origin
San Antonio, TX
Afternoon in San Antonio on Sunday
Local time
2:16 PM
CDT
Current temp
81°F
Unavailable
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Create accountDrive Time
6h
Distance
346.2 mi
557 km
Drive Score
10/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$53
one way
San Antonio, TX
Wikimedia Commons
Lamesa, TX
Thomas balabaud
If you are planning to travel from San Antonio to Lamesa, prepare for a 346.2-mile journey that typically takes about 6 hours of drive time. This route is designed as a single-day trip, meaning you can easily reach your destination by evening without needing an overnight stop. You should budget approximately $52 for fuel to cover the distance across the Great Plains. Because this path relies on local roads rather than major interstates, the pace is steady but requires your full attention. It is a straightforward trek for those who prefer navigating through the heart of Texas rather than sticking to high-speed corridors.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
173.1 miles from San Antonio, TX
A natural place for your longest stop of the day , about 3h into the drive .
Expect a turn-heavy local drive that demands consistent engagement behind the wheel. Unlike a monotonous interstate slog, this route relies on surface streets like West Market Street, Navarro Street, and San Pedro Avenue to get you moving. With 0% highway share, you will experience the road in its most granular form. Don't look for long, uninterrupted stretches of cruising, as the longest segment on West Market Street is effectively zero miles. This drive is best suited for those who don't mind navigating local transit patterns as you transition between urban and rural settings.
This is a straightforward highway drive that stays mostly on I 10 and US Highway 87 North. There are only a few real navigation decisions along the way. The trickiest moment comes around 1.6 miles in near West Cypress Street.
Easy - simple navigation with a manageable amount of wheel time
The route itself is not hard, but at 6h, endurance matters. Plan breaks every 2-3 hours. The 10 decision points are all manageable with basic attention.
Where does it get tricky?
The main spots that need attention: at 1.6 miles (West Cypress Street): Lane positioning matters here; at 3.1 miles: Multiple destination signs - pick the right one; at 3.2 miles (I 10; US 87 / McDermott Freeway): Merge point - match speed before joining. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn left onto West Cypress Street
Lane positioning matters here
Take the ramp toward I 10 West, US 87 North
Multiple destination signs - pick the right one
Merge onto I 10; US 87 / McDermott Freeway
Merge point - match speed before joining. Lane positioning matters here
Keep slight right at fork onto I 10; US 87
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit onto US 83 toward US 83 North, US 377: Junction, Menard
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
On the drive from San Antonio, TX to Lamesa, TX, road signs begin pointing toward Menard along the way.
Menard
| Road | Distance | Duration |
|---|---|---|
| I 10 | 98.7 mi | 1h 37m |
| US Highway 87 North | 75.3 mi | 1h 15m |
| West Broadway Street | 39.2 mi | 39m |
| North Main Street | 29.3 mi | 30m |
| Frisco Avenue | 21.5 mi | 23m |
| South US Highway 87 | 18.1 mi | 18m |
| US 87 | 15.8 mi | 16m |
| North US Highway 87 | 15.2 mi | 15m |
Step-by-step road directions between San Antonio, TX and Lamesa, TX.
Start on Dolorosa Street
Continue on West Market Street
Turn left onto Navarro Street
Enter roundabout onto San Pedro Avenue
Continue on San Pedro Avenue
Turn left onto West Cypress Street
Turn straight onto East Fredericksburg Road
Turn right onto Interstate 10 West
Take the ramp
Merge onto I 10; US 87
Keep slight right at fork onto I 10; US 87
Take the exit onto US 83
Turn right onto US 83; US 377
Continue on US 83
Turn left onto US 87
Continue on US 87; Loop 306
Continue on US 87; US 277
Continue on US 87; US 277; US 67 Bus
Continue on US 87
Continue on US 87
Turn straight onto US 87; TX 158; TX 163
Continue on US 87
Continue on US 87
Continue on US 87
Continue on US 87; US 180
Continue on US 87; US 180
Turn left
Arrive at destination
Since this is a 6-hour trek, departing early in the morning is your best strategy to avoid mid-day traffic congestion on local roads. Plan for at least one dedicated stop to stretch your legs and refresh, as the constant turns can be more fatiguing than highway driving. Keep your fuel gauge in mind and try to fill up before leaving the city limits, as the $52 budget estimate is a baseline for your trip. Because the route is entirely comprised of local roads, stay alert for changing speed limits and intersection transitions. Having a reliable GPS is essential here, as you will be relying on city streets rather than following a single highway sign for the duration of the trip.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 23m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 173.1 miles or 3h in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h
Traffic, exits, and arrival timing usually matter more near Lamesa, TX than in the middle of the route.
Open the route before leaving San Antonio, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from San Antonio, TX
This is one driving day of about 346.2 miles and 6h.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 173.1 mi from San Antonio, TX · 3h into the drive
Mid-route town
Meal stop
173 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 173.1 miles from San Antonio, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 10 if your tank is already low. That segment runs about 98.7 miles.
The final approach into Lamesa, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Lamesa, TX.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$52.88 one way
$105.77 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $57.95 | $115.91 |
| premium | $4.59 | $62.57 | $125.15 |
| diesel | $5.64 | $76.91 | $153.83 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$53
Meals
$25–$50
Total
$78–$103
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 121.1 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $36 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 103.9 | 1 | $36.35 | $16.62 |
| Efficient EV | 86.6 | 0 | $30.29 | $13.85 |
| EV Truck/SUV | 138.5 | 1 | $48.47 | $22.16 |
Gas CO2
121 kg
EV CO2
41 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in San Antonio on Sunday
Local time
2:16 PM
CDT
Current temp
81°F
Unavailable
Destination
Afternoon in Lamesa on Sunday
Local time
2:16 PM
CDT
Current temp
52°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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