Origin
San Antonio, TX
Afternoon in San Antonio on Sunday
Local time
2:18 PM
CDT
Current temp
81°F
Unavailable
Live forecast
Trip from San Antonio, TX to Odessa, TX
Drive Time
5h 55m
Distance
340.2 mi
548 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$52
one way
San Antonio, TX
Wikimedia Commons
Odessa, TX
Thomas balabaud
Trip Overview
Spanning 340.2 miles across the heart of Texas, your journey from San Antonio to Odessa is a manageable trek that typically takes about 5 hours and 55 minutes. You will navigate primarily via local roads like West Market Street, Navarro Street, and San Pedro Avenue rather than high-speed interstates. Budgeting approximately $51 for fuel is a smart starting point for your planning. Because this route involves a turn-heavy local profile, it is best suited as a single-day trip if you are comfortable with sustained attention at the wheel. Both cities are situated within the Great Plains region, offering a consistent environmental backdrop as you head west across the state.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
170.1 miles from San Antonio, TX
A natural place for your longest stop of the day , about 2h 48m into the drive .
Drive Character
Expect a very different experience than a standard interstate cruise, as this route features a 0% highway share. You will be navigating a turn-heavy, local-road drive that demands your full attention behind the wheel. Because there are no long, uninterrupted highway stretches, the pace of the drive remains consistent and engaging throughout the 340.2-mile journey. Your time will be spent navigating urban and local thoroughfares, which creates a distinct, hands-on feel compared to the monotony of a typical freeway transit. Stay alert and prepared for frequent adjustments as you maneuver through the local road network.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 18 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 10 is the longest continuous segment at about 247.5 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 10 and US 385. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.2 miles in near Navarro Street.
Route Complexity
5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 340.2 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.2 miles (Navarro Street): Lane positioning matters here; at 1.6 miles (West Cypress Street): Lane positioning matters here; at 3.1 miles: Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 11 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
6
0.2 mi into trip
|
~0m in
|
Navarro Street
Turn left onto Navarro Street
Lane positioning matters here
Use the none lane.
5
1.6 mi into trip
|
~3m in
|
West Cypress Street
Turn left onto West Cypress Street
Lane positioning matters here
Use the left lane.
5
3.1 mi into trip
|
~5m in
Take the ramp toward I 10 West, US 87 North
Multiple destination signs - pick the right one
Toward I 10 West, US 87 North
6
16.1 mi into trip
|
~20m in
|
I 10; US 87
Keep slight right at fork onto I 10; US 87
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight left / none lanes.
6
263.5 mi into trip
|
~4h 17m in
Take the exit toward US 190, FM 305: Iraan, McCamey
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 307
Toward US 190, FM 305: Iraan, McCamey
Towns Along This Route
Between San Antonio, TX and Odessa, TX, road signs point toward Fm 305: Iraan and Mccamey.
Fm 305: Iraan
263.5 mi in
|
~4h 17m
Mccamey
263.5 mi in
|
~4h 17m
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 10 | 247.5 mi | 3h 56m |
| US 385 | 52 mi | 1h 1m |
| Farm to Market Road 305 | 18.1 mi | 26m |
| McDermott Freeway | 12.8 mi | 14m |
| US 190 | 4 mi | 5m |
| South Burleson Avenue | 2.3 mi | 3m |
| East Fredericksburg Road | 1.2 mi | 2m |
| Navarro Street | 0.8 mi | 1m |
Longest stretch:
I 10
— 247.5 mi, about 3h 56m
Turn-by-Turn Driving Directions
Step-by-step road directions between San Antonio, TX and Odessa, TX.
1
Start on Dolorosa Street
143 ft
·
4 sec
·
Dolorosa Street
2
Continue on West Market Street
0.2 mi
·
28 sec
·
West Market Street
3
Turn left onto Navarro Street
0.8 mi
·
1 min
·
Navarro Street
Use the none lane.
4
Enter roundabout onto San Pedro Avenue
85 ft
·
1 sec
·
San Pedro Avenue
5
Continue on San Pedro Avenue
0.5 mi
·
1 min
·
San Pedro Avenue
Use the none lane.
6
Turn left onto West Cypress Street
0.1 mi
·
10 sec
·
West Cypress Street
Use the left lane.
7
Turn straight onto East Fredericksburg Road
1.2 mi
·
2 min
·
East Fredericksburg Road
Use the none lane.
8
Turn right onto Interstate 10 West
0.1 mi
·
13 sec
·
Interstate 10 West
9
Take the ramp
0.1 mi
·
13 sec
Toward I 10 West, US 87 North
10
Merge onto I 10; US 87
13 mi
·
14 min
·
McDermott Freeway
Use the none / straight / slight right lanes.
11
Keep slight right at fork onto I 10; US 87
247 mi
·
3 hr 56 min
·
I 10; US 87
Use the straight / slight left / none lanes.
12
Take the exit
0.2 mi
·
29 sec
Exit 307
Toward US 190, FM 305: Iraan, McCamey
13
Continue on I 10 Service Road
0.1 mi
·
18 sec
·
I 10 Service Road
14
Turn right onto US 190
4.0 mi
·
5 min
·
US 190
15
Turn left onto FM 305
18 mi
·
26 min
·
Farm to Market Road 305
16
Continue on FM 305
2.3 mi
·
3 min
·
South Burleson Avenue
17
Continue on US 385
52 mi
·
1 hr 1 min
·
US 385
Use the none lane.
18
Arrive at destination
US 385
Trip Plan
Since this is a nearly six-hour drive, departing early in the morning is your best strategy to avoid the stress of navigating local roads in heavy traffic. Plan for at least one stop to stretch your legs and refuel, keeping your $51 budget in mind as you pace your progress. Because this is a turn-heavy route, ensure your GPS is updated and ready to handle frequent directional changes before you leave San Antonio. Flexibility is your greatest asset here; since the drive is well within the limits of a single day, you can easily adjust your pace to accommodate local traffic patterns. Keep a close watch on your fuel gauge when navigating away from major intersections to avoid unnecessary detours.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 170.1 miles from San Antonio, TX, or about 2h 48m into the drive.
The longest continuous stretch on this route runs about 247.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 22m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 170.1 miles or 2h 48m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 42m
Traffic, exits, and arrival timing usually matter more near Odessa, TX than in the middle of the route.
Before You Leave
+
Open the route before leaving San Antonio, TX so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from San Antonio, TX
This is one driving day of about 340.2 miles and 5h 55m.
Your first comfortable stop window is around 80 miles from San Antonio, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 10 for about 247.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 170.1 mi from San Antonio, TX · 2h 48m into the drive
Mid-route town
Meal stop
170 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 80 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 170.1 miles from San Antonio, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 10 if your tank is already low. That segment runs about 247.5 miles.
Arriving in Odessa, TX
The final approach into Odessa, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Odessa, TX.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$51.97 one way
$103.94 round trip
$3.88/gal
25.4 MPG avg
119 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $56.95 | $113.90 |
| premium | $4.59 | $61.49 | $122.98 |
| diesel | $5.64 | $75.58 | $151.16 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$52
Meals
$25–$50
Total
$77–$102
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 119 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $36 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 102.1 | 1 | $35.72 | $16.33 |
| Efficient EV | 85.1 | 0 | $29.77 | $13.61 |
| EV Truck/SUV | 136.1 | 1 | $47.63 | $21.77 |
Gas CO2
119 kg
EV CO2
40 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Odessa, TX
Afternoon in Odessa on Sunday
Local time
2:18 PM
CDT
Current temp
58°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
23 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 55m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from San Antonio, TX to Odessa, TX covers 340.2 miles and takes about 5h 55m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 10, US 385, Farm to Market Road 305. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 170.1 miles from San Antonio, TX. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $51.97 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This drive requires moderate attention. Across 340.2 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: at 0.2 miles (Navarro Street): Lane positioning matters here; at 1.6 miles (West Cypress Street): Lane positioning matters here; at 3.1 miles: Multiple destination signs - pick the right one.
Between San Antonio, TX and Odessa, TX, road signs point toward Fm 305: Iraan and Mccamey.
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