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Trip from Shrewsbury, MO to Cape Girardeau, MO

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

2h 9m

Distance

111.3 mi

179 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$17

one way

EV Charging

Unknown

Best Time to Leave

Save up to 27 min
4 AM
2h 1m ★
6 AM
2h 10m
8 AM
2h 28m
10 AM
2h 16m
12 PM
2h 14m
3 PM
2h 17m
5 PM
2h 27m
8 PM
2h 4m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in St. Louis County, Missouri, United States

Shrewsbury, MO

Wikimedia Commons

city in Cape Girardeau and Scott Counties in the U.S. state of Missouri

Cape Girardeau, MO

Wikimedia Commons

Trip Overview

The drive from Shrewsbury, MO to Cape Girardeau, MO covers 111.3 miles and takes about 2h 9m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on I 55, North Kingshighway, Broadway Street for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 99.2 miles on I 55. At current regular gas prices, budget about $17.40 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Midpoint

55.6 miles from Shrewsbury, MO

A natural place for your longest stop of the day , about 1h 5m into the drive .

Main Roads

Road Distance Duration
I 55 99.2 mi 1h 47m
North Kingshighway 3.6 mi 6m
Broadway Street 2 mi 3m
Mackenzie Road 2 mi 4m
Laclede Station Road 1.8 mi 3m
Heege Road 1 mi 2m
Reavis Barracks Road 0.7 mi 1m
Police Officer Robert Stanze Memorial Highway 0.1 mi <1m
Longest stretch: I 55 — 99.2 mi, about 1h 47m

Turn-by-Turn Driving Directions

Step-by-step road directions between Shrewsbury, MO and Cape Girardeau, MO.

1

Start on I 44

0.1 mi · 9 sec · Police Officer Robert Stanze Memorial Highway
2

Take the exit

0.1 mi · 18 sec
Exit 282 Toward Laclede Station Road, Murdoch Avenue Use the slight right lane.
3

Turn right onto Laclede Station Road

1.8 mi · 3 min · Laclede Station Road
Use the left lane.
4

Turn left onto Heege Road

1.0 mi · 2 min · Heege Road
5

Turn right onto MO P

2.0 mi · 4 min · Mackenzie Road
6

Turn straight onto Reavis Barracks Road

0.7 mi · 1 min · Reavis Barracks Road
7

Take the ramp

0.2 mi · 14 sec
Toward I 55 South
8

Merge onto I 55

99 mi · 1 hr 47 min · I 55
Use the straight / slight right lanes.
9

Take the exit

0.2 mi · 17 sec
Exit 99 Toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
10

Keep slight left at fork

0.3 mi · 28 sec
Exit 99 Toward I 55 Business, US 61 South, MO 34 East: Cape Girardeau
11

Continue on I 55 Bus; US 61; MO 34

3.6 mi · 6 min · North Kingshighway
12

Turn left onto Broadway Street

2.0 mi · 3 min · Broadway Street
13

Arrive at destination

Broadway Street

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 55.6 miles from Shrewsbury, MO, or about 1h 5m into the drive.
The longest continuous stretch on this route runs about 99.2 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 24 miles or 31m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 55.6 miles or 1h 5m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 44m

Traffic, exits, and arrival timing usually matter more near Cape Girardeau, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Shrewsbury, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Shrewsbury, MO

This is one driving day of about 111.3 miles and 2h 9m.

Your first comfortable stop window is around 24 miles from Shrewsbury, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on I 55 for about 99.2 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

census-designated place in Missouri, United States

Mid-route town

Meal stop

Imperial, MO

56 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Arnold, MO

Fuel and coffee

A short stop after about 24 miles helps settle the day before fatigue starts building.

Imperial, MO

Meal break

The midpoint is around 55.6 miles from Shrewsbury, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 55 if your tank is already low. That segment runs about 99.2 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 9

5 decision points cluster between mile 0.1 and 105.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

9
0.1 mi into trip | ~0m in

Take the exit toward Laclede Station Road, Murdoch Avenue

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 282 Toward Laclede Station Road, Murdoch Avenue
4
0.2 mi into trip | ~0m in | Laclede Station Road

Turn right onto Laclede Station Road

Lane positioning matters here

Use the left lane.
5
6 mi into trip | ~11m in | I 55

Merge onto I 55

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
6
105.2 mi into trip | ~1h 59m in

Take the exit toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 99 Toward US 61, MO 34, I 55 Business: Cape Girard...
8
105.3 mi into trip | ~1h 59m in

Keep slight left at fork toward I 55 Business, US 61 South, MO 34 East: Cape Girardeau

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Exit 99 Toward I 55 Business, US 61 South, MO 34 East:...

Fuel & Cost

Regular Gas

$17.40 one way

$34.80 round trip

$3.97/gal 25.4 MPG avg 39 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $19.11 $38.21
premium $4.89 $21.42 $42.84
diesel $5.61 $24.57 $49.15

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$17

Meals

$25–$50

Total

$42–$67

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 38.9 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $12 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 33.4 0 $11.69 $5.34
Efficient EV 27.8 0 $9.74 $4.45
EV Truck/SUV 44.5 0 $15.58 $7.12

Gas CO2

39 kg

EV CO2

13 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 17, 2026

Origin

Shrewsbury, MO

Afternoon in Shrewsbury on Saturday

Local time

1:22 PM

CDT

Current temp

63°F

Unavailable

Live forecast

Destination

Cape Girardeau, MO

Afternoon in Cape Girardeau on Saturday

Local time

1:22 PM

CDT

Current temp

81°F

Unavailable

Live forecast

57°F

Imperial, MO

56 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

18 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 9m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

111.3 mi in 2h 9m, mostly highway — 99.2 mi of that is on I 55.

89% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 99.2 mi on I 55.

How Hard Is This Drive?

4/10

This is a straightforward highway drive that stays mostly on I 55 and North Kingshighway. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.1 miles in.

Driving Effort 4/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

This is a straightforward 2h 9m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: at 0.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 0.2 miles (Laclede Station Road): Lane positioning matters here; at 6 miles (I 55): Merge point - match speed before joining. Lane positioning matters here.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Shrewsbury, MO to Cape Girardeau, MO, road signs begin pointing toward Jackson along the way.

Jackson

105.2 mi in | ~1h 59m

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 9m. Total distance: 111.3 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

2h 9m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (89%). Straightforward navigation.

Frequently Asked Questions

The longest stretch is about 99.2 miles on I 55. The full list of main roads is in the Roads section above.

Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.

The main spots that need attention: at 0.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 0.2 miles (Laclede Station Road): Lane positioning matters here; at 6 miles (I 55): Merge point - match speed before joining. Lane positioning matters here.

Yes. A round trip is manageable in a single day if you plan a break at Cape Girardeau, MO before heading back.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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