Trip from Tallahassee, FL to Key West, FL

Drive Time

12h 40m

Distance

637.8 mi

1,026 km

Drive Score

7/10

Good drive

Same Day?

2-day trip

Fuel Cost

$107

one way

EV Charging

Loading...

station data

Best Time to Leave

Save up to 34 min
4 AM
12h 29m ★
6 AM
12h 40m
8 AM
13h 3m
10 AM
12h 48m
12 PM
12h 46m
3 PM
12h 49m
5 PM
13h 2m
8 PM
12h 33m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Key West, FL, FL

Key West, FL

Arian Fernandez

Trip Overview

The drive from Tallahassee, FL to Key West, FL covers 637.8 miles and takes about 12h 40m behind the wheel. It usually feels better as a 2-day road trip than as one long push.

The route leans on East Pensacola Street, South Franklin Boulevard, East Tennessee Street for much of the mileage, and the overall profile is long-distance drive. At current regular gas prices, budget about $106.54 one way before food or hotel costs.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

3 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

318.9 miles from Tallahassee, FL

A natural place for your longest stop of the day , about 6h 20m into the drive .

Drive Character

At 637.8 miles and 12h 40m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are East Pensacola Street and South Franklin Boulevard.

Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 18 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
East Pensacola Street is one of the defining roads on this drive.

How Hard Is This Drive?

At 12h 40m, this is a long-haul route where pacing matters more than any single turn. There are only a few real navigation decisions along the way.

Route Complexity 4/10

Easy - simple navigation with a manageable amount of wheel time

The route itself is not hard, but at 12h 40m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Tallahassee, FL to Key West, FL is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
East Pensacola Street Unavailable Refreshing
South Franklin Boulevard Unavailable Refreshing
East Tennessee Street Unavailable Refreshing
Mahan Drive Unavailable Refreshing
I 10 East Unavailable Refreshing
I-75 South Unavailable Refreshing
Florida's Turnpike South Unavailable Refreshing
Florida's Turnpike Toll South Unavailable Refreshing

Per-road distance and duration are being refreshed from OSRM for this route.

Longest stretch: East Pensacola Street — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Tallahassee, FL and Key West, FL.

1

Start on South Monroe Street

180 ft · 8 sec · South Monroe Street
2

Turn right onto East Pensacola Street

0.3 mi · 47 sec · East Pensacola Street
3

Turn left onto South Franklin Boulevard

0.5 mi · 1 min · South Franklin Boulevard
4

Turn right onto East Tennessee Street

0.6 mi · 1 min · East Tennessee Street
5

Continue on Mahan Drive

6.5 mi · 11 min · Mahan Drive
6

Take the ramp slight right toward I 10 East: Lake City

0.7 mi · 1 min · I 10 East: Lake City
7

Merge slight left

87 mi · 1 hr 33 min
8

Take the exit slight right toward I-75 South: Tampa

0.4 mi · 37 sec · I-75 South: Tampa
9

Merge slight left

107 mi · 1 hr 54 min
10

Take the exit slight left toward Florida's Turnpike South, Orlando

261 mi · 4 hr 43 min · Florida's Turnpike South, Orlando
11

Take the exit slight right toward Florida's Turnpike Toll South, Homestead

0.2 mi · 20 sec · Florida's Turnpike Toll South, Homestead
12

Keep slight left to continue on Homestead Extension of Florida's Turnpike

47 mi · 54 min · Homestead Extension of Florida's Turnpike
13

Keep slight left

0.6 mi · 1 min
14

Merge slight left onto Dixie Highway

19 mi · 26 min · Dixie Highway
15

Continue on Overseas Highway

104 mi · 2 hr 42 min · Overseas Highway
16

Turn right onto North Roosevelt Boulevard

2.4 mi · 5 min · North Roosevelt Boulevard
17

Turn left onto George Street

0.3 mi · 1 min · George Street
18

Arrive at your destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.
Plan roughly 3 meaningful breaks for fuel, food, and rest.
The halfway point lands around 318.9 miles from Tallahassee, FL, or about 6h 20m into the drive.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 140 miles or 2h 46m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 318.9 miles or 6h 20m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 318.9 miles or 6h 20m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 11h 28m

Traffic, exits, and arrival timing usually matter more near Key West, FL than in the middle of the route.

Before You Leave

+

Open the route before leaving Tallahassee, FL so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

+

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Tallahassee, FL

Aim for roughly 319 miles and 6.3 hours of wheel time on this day.

Day 2

Finish the approach into Key West, FL

Aim for roughly 319 miles and 6.3 hours of wheel time on this day.

Your first comfortable stop window is around 140 miles from Tallahassee, FL.
This route usually feels better as a 2-day drive than as one long push.
Plan about 3 real breaks rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 318.9 mi from Tallahassee, FL · 6h 20m into the drive

Downtown Palm Bay, FL, FL

First major stop

Coffee and fuel

Palm Bay, FL

210 mi into the route

Best for: Coffee, fuel, and an easy first stretch

This is a natural early stop once the first hours of the drive are behind you.

Downtown Doral, FL, FL

Second major stop

Overnight candidate

Doral, FL

421 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Doral, FL

Overnight Options

Night 1

Pembroke Pines, FL

319 mi · about 6.3h in

A practical overnight split lands near Pembroke Pines, FL after about 319 miles or 6.3 hours of driving.

Find hotels

Pacing Suggestions

Orlando, FL

Fuel and coffee

A short stop after about 140 miles helps settle the day before fatigue starts building.

Pembroke Pines, FL

Meal break

The midpoint is around 318.9 miles from Tallahassee, FL, which is a good place for a longer meal and fuel stop.

Overnight split

Hotel stop

For a steadier pace, wrap day one after about 319 miles or 6.3 hours on the road.

Final-third reset

Rest stop

Plan one more short stretch-and-water break in the final third of the drive so the last arrival window feels easier.

Arriving in Key West, FL

The final approach into Key West, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Key West, FL.

On a multi-day trip, keep the last day a little lighter so you reach Key West, FL with some flexibility left in the schedule.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$106.54 one way

$213.09 round trip

$4.24/gal 25.4 MPG avg 223 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.60 $115.41 $230.81
premium $4.90 $122.94 $245.88
diesel $5.64 $141.70 $283.39

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$107

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$237–$347

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 223.2 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $67 in charging · 2 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 191.3 2 $66.97 $30.61
Efficient EV 159.5 1 $55.81 $25.51
EV Truck/SUV 255.1 3 $89.29 $40.82

Gas CO2

223 kg

EV CO2

75 kg (66% less)

Plan for 2 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Tallahassee, FL

Afternoon in Tallahassee on Monday

Local time

1:48 PM

EDT

Current temp

61°F

Unavailable

Live forecast

Destination

Key West, FL

Afternoon in Key West on Monday

Local time

1:48 PM

EDT

Current temp

75°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

14 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

12h 40m on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Tallahassee, FL to Key West, FL covers 637.8 miles and takes about 12h 40m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are East Pensacola Street, South Franklin Boulevard, East Tennessee Street. Expect a mix of highway and local road driving.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 319 miles on day one.
The midpoint is about 318.9 miles from Tallahassee, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $106.54 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 3 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 12h 40m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from Tallahassee, FL to Key West, FL is straightforward, with well-signed roads and simple exits.
The route from Tallahassee, FL to Key West, FL does not surface many named destination signs beyond the main corridor.

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