Origin
Tupelo, MS
Late night in Tupelo on Friday
Local time
4:53 AM
CDT
Current temp
78°F
Unavailable
Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards
Drive Time
5h 44m
Distance
295.1 mi
475 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$45
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Tupelo, MS
Wikimedia Commons
Lyman, MS
Zsolt Pujsz
This 295.1-mile journey from Tupelo, Mississippi, to Lyman, Mississippi, is designed as a single-day adventure, clocking in at approximately 5 hours and 44 minutes of pure driving time. You'll spend about 95% of your time on highways, making it a focused drive through the Southeast region. With an estimated fuel cost of $45, it's an economical option for a quick getaway. This route is best tackled in one go, allowing you to cover significant ground efficiently without the need for an overnight stop. Consider this a straightforward trip to get you from point A to B with minimal fuss.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
147.6 miles from Tupelo, MS
A natural place for your longest stop of the day , about 2h 54m into the drive .
Weekend Trip
Doable as a same-day drive at 5h 44m. Total distance: 295.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 44m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (95%). Some complex stretches to watch for.
Expect a highway-focused experience for the majority of your drive, with 95% of the route utilizing major roads like I-59 and US Highway 45 Alternate. This means you'll be covering distance at a steady pace for most of the trip. The longest uninterrupted stretch you'll encounter is 88.7 miles on I-59, offering a good period to settle in and maintain momentum. While primarily highway, this kind of drive often involves transitions between different arterial roads, so be prepared for those shifts. It's a practical path designed for efficient travel.
This is a straightforward highway drive that stays mostly on I 59 and US Highway 45 Aiternate. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 147 miles in near I 59.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 295.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 147 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 235.7 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 238.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight left at fork onto I 59 toward I 59 South: Laurel, New Orleans
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Turn right onto US 49
Lane positioning matters here
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Tupelo, MS and Lyman, MS, road signs point toward New Orleans, Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.
New Orleans
Mobile
Gulfport
Mississippi Gulf Coast
Multi Purpose Center
Hattiesburg
| Road | Distance | Duration |
|---|---|---|
| I 59 | 88.7 mi | 1h 36m |
| US Highway 45 Aiternate | 60.6 mi | 1h 9m |
| US Highway 45 Alternate | 54.7 mi | 1h 6m |
| US 49 | 53.1 mi | 1h 2m |
| Martin Luther King Drive | 8.7 mi | 10m |
| I 20 | 8.1 mi | 9m |
| US 45 ALT | 7.2 mi | 8m |
| US 45 | 3.9 mi | 4m |
Step-by-step road directions between Tupelo, MS and Lyman, MS.
Start on North Spring Street
Turn right onto Court Street
Turn right onto North Front Street
Turn left onto East Main Street
Take the ramp
Merge onto US 45; MS 6
Continue on US 45; MS 6
Continue on US 45; US 278
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45 ALT
Continue on US 45
Keep slight right at fork onto US 45
Take the exit
Merge onto I 20; I 59
Continue on I 20; I 59; US 80
Keep slight left at fork onto I 59
Take the exit onto US 98
Take the exit
Keep slight left at fork
Turn right onto US 49
Turn right onto MS 53
Turn left onto Lumpkin Road
Turn left onto Price Road
Arrive at destination
To maximize your daylight and minimize traffic, aim for an early morning departure from Tupelo. With a total driving time under six hours, this trip is comfortably manageable in a single day, so you have the flexibility to stop as needed without feeling rushed. Factor in at least one brief stop to stretch your legs and refuel. Given the significant highway mileage, particularly the 88.7-mile stretch on I-59, be mindful of your fuel gauge as services can sometimes be spread out on these longer highway segments. This route is primarily about efficient travel, so keeping moving is key.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 65 miles or 1h 19m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 147.6 miles or 2h 54m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 38m
Traffic, exits, and arrival timing usually matter more near Lyman, MS than in the middle of the route.
Open the route before leaving Tupelo, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Tupelo, MS
This is one driving day of about 295.1 miles and 5h 44m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 147.6 mi from Tupelo, MS · 2h 54m into the drive
Mid-route town
Meal stop
148 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 65 miles helps settle the day before fatigue starts building.
The midpoint is around 147.6 miles from Tupelo, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 59 if your tank is already low. That segment runs about 88.7 miles.
The final approach into Lyman, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Lyman, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$44.57 one way
$89.13 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $48.92 | $97.85 |
| premium | $4.56 | $52.97 | $105.93 |
| diesel | $5.61 | $65.15 | $130.31 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$45
Meals
$25–$50
Total
$70–$95
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 103.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $31 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 88.5 | 1 | $30.99 | $14.16 |
| Efficient EV | 73.8 | 0 | $25.82 | $11.80 |
| EV Truck/SUV | 118 | 1 | $41.31 | $18.89 |
Gas CO2
103 kg
EV CO2
35 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Tupelo on Friday
Local time
4:53 AM
CDT
Current temp
78°F
Unavailable
Destination
Late night in Lyman on Friday
Local time
4:53 AM
CDT
Current temp
65°F
Unavailable
79°F
Meridian, MS
148 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from OSRM over OpenStreetMap. Fuel cost uses EIA weekly regional averages. Pages are published only after passing our data-quality checks; our methodology page documents refresh cadence, editorial standards, and known limitations.
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