The drive from Uniontown, MO to Independence, MO covers 318.2 miles and takes about 6h 10m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D Eisenhower Highway, I 55, U.S. Submarine Veterans' Memorial Highway for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 80.7 miles on Dwight D Eisenhower Highway.
At current regular gas prices, budget about $49.75 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
159.1 miles from Uniontown, MO
A natural place for your longest stop of the day
, about 3h 11m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 10m. Total distance: 318.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 10m drive, plan rest stops for pacing.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a 6h 10m drive with frequent turns across 318.2 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 32 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D Eisenhower Highway is the longest continuous segment at about 80.7 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 78.6 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 318.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 78.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 78.8 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 91.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 18 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
78.6 mi into trip|~1h 33m in
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chi...
8
78.8 mi into trip|~1h 33m in
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left lane.
Toward I 270 West: Kansas City
8
91.1 mi into trip|~1h 49m in
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Lo...
8
91.2 mi into trip|~1h 49m in
Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 64 West, US 40 West, US 61 North: Went...
8
117.2 mi into trip|~2h 21m in|US 40
Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight left lanes.
Exit 1A
Toward I 70 West, US 40 West: Kansas City
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Uniontown, MO and Independence, MO, road signs point toward Chicago and Saint Louis.
Chicago
78.6 mi in|~1h 33m
Saint Louis
91.1 mi in|~1h 49m
Main Roads
Road
Distance
Duration
Dwight D Eisenhower Highway
80.7 mi
1h 35m
I 55
59.4 mi
1h 4m
U.S. Submarine Veterans' Memorial Highway
54.4 mi
58m
Dwight D. Eisenhower Highway
54.3 mi
58m
Avenue of the Saints
25.4 mi
30m
US 61
11.8 mi
17m
I 270
11.5 mi
14m
South Noland Road
3 mi
5m
Longest stretch:
Dwight D Eisenhower Highway
— 80.7 mi, about 1h 35m
Turn-by-Turn Driving Directions
Step-by-step road directions between Uniontown, MO and Independence, MO.
1
Start on PCR 531
25 ft·2 sec·Perry County Road 531
2
Turn left onto US 61
12 mi·17 min·US 61
3
Enter roundabout onto US 61
128 ft·2 sec·North Kingshighway Street
4
Continue on US 61
2.4 mi·3 min·North Kingshighway Street
5
Continue on US 61
2.8 mi·4 min·North King's Highway
6
Turn left onto MO M
0.5 mi·1 min·MO M
7
Take the ramp
0.2 mi·27 sec
Toward I 55 North: Saint Louis
8
Merge onto I 55
59 mi·1 hr 4 min·I 55
9
Continue on I 55
1.3 mi·1 min·Rosa Parks Highway
10
Take the exit
0.2 mi·27 sec
Exit 196Toward I 270 West, I 255 East: Kansas City, ChicagoUse the slight right lane.
11
Keep slight left at fork
388 ft·8 sec
Toward I 270 West: Kansas CityUse the slight left lane.
12
Continue on this road
0.7 mi·1 min·this road
Exit 196Toward I 270 West
13
Merge onto I 270
11 mi·14 min·I 270
Use the straight lane.
14
Take the exit
0.1 mi·17 sec
Exit 12Toward I 64, US 40, US 61: Wentzville, Saint LouisUse the slight right lane.
15
Keep slight left at fork
0.4 mi·48 sec
Toward I 64 West, US 40 West, US 61 North: WentzvilleUse the slight left lane.
16
Continue on this road
0.1 mi·9 sec·this road
Exit 12Toward I 64 West, US 40 West, US 61 North: Wentzville
17
Merge onto I 64; US 40; US 61
25 mi·30 min·Avenue of the Saints
Use the straight lane.
18
Take the exit onto US 40
0.6 mi·1 min·US 40
Exit 1AToward I 70 West, US 40 West: Kansas CityUse the straight / slight left lanes.
19
Merge onto I 70; US 40
81 mi·1 hr 35 min·Dwight D Eisenhower Highway
20
Continue on I 70; US 40
2.0 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
21
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
22
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
23
Continue on I 70; US 40
54 mi·58 min·U.S. Submarine Veterans' Memorial Highway
The midpoint is around 158.7 miles from Uniontown, MO, which is a good place for a longer meal and fuel stop.
Arriving in Independence, MO
The final approach into Independence, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Independence, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Ste. Geneviève National Historical Park
National Historical Park
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
5 mi from route
~13 min detour
Free
near mile 32.9
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
14 mi from route
~35 min detour
$19
near mile 76.8
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$49.75 one way
$99.49 round trip
$3.97/gal25.4 MPG avg111 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$54.62
$109.24
premium
$4.89
$61.23
$122.47
diesel
$5.61
$70.25
$140.51
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$50
Meals
$25–$50
Total
$75–$100
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 111.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $33 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
95.5
1
$33.41
$15.27
Efficient EV
79.6
0
$27.84
$12.73
EV Truck/SUV
127.3
1
$44.55
$20.36
Gas CO2
111 kg
EV CO2
37 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Uniontown, MO
Night
in Uniontown on Thursday
Local time
11:27 PM
CDT
Current temp
53°F
Unavailable
Live forecast
Destination
Independence, MO
Night
in Independence on Thursday
Local time
11:27 PM
CDT
Current temp
73°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
20 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 10m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Uniontown, MO to Independence, MO covers 318.2 miles and takes about 6h 10m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D Eisenhower Highway, I 55, U.S. Submarine Veterans' Memorial Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 159.1 miles from Uniontown, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $49.75 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 318.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 78.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 78.8 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 91.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Uniontown, MO and Independence, MO, road signs point toward Chicago and Saint Louis.
