The drive from Winston-Salem, NC to Saint James, NC covers 237.4 miles and takes about 4h 51m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 74, Andrew Jackson Highway, American Indian Highway for much of the mileage,
and the overall profile is mixed drive.
The longest uninterrupted segment is about 89 miles on I 74.
At current regular gas prices, budget about $37.12 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
118.7 miles from Winston-Salem, NC
A natural place for your longest stop of the day
, about 2h 21m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 51m. Total distance: 237.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 51m drive, comfortable solo distance.
Scenic Drive
Mixed drive route profile with national parks nearby.
Drive Character
The drive from Winston-Salem, NC to Saint James, NC covers 237.4 miles and takes about 4h 51m, using a mix of highways and local roads.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 29 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 74 is the longest continuous segment at about 89 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.5 miles in.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 237.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.5 miles: Multiple destination signs - pick the right one; at 0.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 3.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Critical Maneuvers
5 of 18 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
0.5 mi into trip|~0m in
Take the ramp toward US 158 East, US 421 South, NC 150 East
Multiple destination signs - pick the right one
Toward US 158 East, US 421 South, NC 150 East
8
0.9 mi into trip|~1m in
Take the exit toward US 52 South: Lexington
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 232C
Toward US 52 South: Lexington
7
3.4 mi into trip|~5m in
Take the exit toward I 40 East: Greensboro
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / right lanes.
Exit 107A
Toward I 40 East: Greensboro
7
5.9 mi into trip|~8m in|I 74
Take the exit onto I 74 toward I 74 East: High Point
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 196
Toward I 74 East: High Point
7
94.9 mi into trip|~1h 48m in|US 220
Take the exit onto US 220 toward US 220 South: Rockingham
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 22
Toward US 220 South: Rockingham
Main Roads
Road
Distance
Duration
I 74
89 mi
1h 39m
Andrew Jackson Highway
44.3 mi
49m
American Indian Highway
33.6 mi
36m
NC 211
25.4 mi
34m
East Hamlet Avenue
12.8 mi
16m
Southport-Supply Road Southeast
9 mi
12m
US 220
4.8 mi
6m
Hamlet Avenue
3.5 mi
5m
Longest stretch:
I 74
— 89 mi, about 1h 39m
Turn-by-Turn Driving Directions
Step-by-step road directions between Winston-Salem, NC and Saint James, NC.
1
Start on North Main Street
0.5 mi·59 sec·North Main Street
Use the straight / right lanes.
2
Take the ramp
0.2 mi·22 sec
Toward US 158 East, US 421 South, NC 150 East
3
Merge onto US 421; US 158; NC 150
0.3 mi·21 sec·Salem Parkway
4
Take the exit
0.2 mi·31 sec
Exit 232CToward US 52 South: LexingtonUse the slight right lane.
5
Merge onto US 52; NC 8
2.2 mi·3 min·John Gold Memorial Expressway
Use the straight / slight right lanes.
6
Take the exit
0.3 mi·31 sec
Exit 107AToward I 40 East: GreensboroUse the straight / right lanes.
7
Merge onto I 40
2.2 mi·2 min·I 40
8
Take the exit onto I 74
89 mi·1 hr 39 min·I 74
Exit 196Toward I 74 East: High PointUse the straight / slight right lanes.
9
Take the exit onto US 220
4.8 mi·6 min·US 220
Exit 22Toward US 220 South: RockinghamUse the straight / slight right lanes.
10
Turn left onto US 74 BUS
2.5 mi·4 min·West Broad Avenue
11
Continue on US 74 BUS
3.5 mi·5 min·Hamlet Avenue
12
Turn left onto US 74 BUS
466 ft·11 sec·Raleigh Street
13
Turn right onto US 74 BUS
0.3 mi·41 sec·Spring Street
14
Turn slight left onto East Hamlet Avenue
13 mi·16 min·East Hamlet Avenue
15
Keep slight right at fork onto US 74
10 mi·10 min·Andrew Jackson Highway
Use the straight / slight right lanes.
16
Continue on US 74
34 mi·36 min·American Indian Highway
17
Continue on US 74; NC 130
34 mi·38 min·Andrew Jackson Highway
18
Take the exit
0.4 mi·46 sec
19
Turn right onto NC 211
25 mi·34 min·NC 211
20
Continue on NC 211
9.0 mi·12 min·Southport-Supply Road Southeast
Use the left / straight / right lanes.
21
Turn right onto NC 906
3.0 mi·4 min·Middleton Street
Use the right lane.
22
Turn slight left onto St James Drive Southeast
97 ft·4 sec·St James Drive Southeast
23
Continue on St James Drive Southeast
1.9 mi·7 min·St James Drive Southeast
24
Continue on Trailwood Drive Southeast
365 ft·16 sec·Trailwood Drive Southeast
25
Continue on St James Drive Southeast
0.6 mi·2 min·St James Drive Southeast
26
Enter roundabout onto St James Drive Southeast
245 ft·11 sec·St James Drive Southeast
27
Continue on St James Drive Southeast
0.3 mi·1 min·St James Drive Southeast
28
Turn left
118 ft·8 sec
29
Arrive at destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 118.7 miles from Winston-Salem, NC, or about 2h 21m into the drive.
The longest continuous stretch on this route runs about 89 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 52 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 118.7 miles or 2h 21m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 45m
Traffic, exits, and arrival timing usually matter more near Saint James, NC than in the middle of the route.
Before You Leave
+
Open the route before leaving Winston-Salem, NC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Winston-Salem, NC
This is one driving day of about 237.4 miles and 4h 51m.
Your first comfortable stop window is around 52 miles from Winston-Salem, NC.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 74 for about 89 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 118.7 mi from Winston-Salem, NC
· 2h 21m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Moores Creek National Battlefield
National Battlefield
In the early morning hours of February 27, 1776, Loyalist forces charged across a partially dismantled Moores Creek Bridge. Beyond the bridge, nearly 1,000 North Carolina Patriots waited quietly with...
20 mi from route
~51 min detour
Free
near mile 196.5
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$37.12 one way
$74.25 round trip
$3.97/gal25.4 MPG avg83 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.34
$40.59
$81.18
premium
$4.70
$43.94
$87.88
diesel
$5.61
$52.41
$104.83
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$37
Meals
$25–$50
Total
$62–$87
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 83.1 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $25 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
71.2
0
$24.93
$11.40
Efficient EV
59.4
0
$20.77
$9.50
EV Truck/SUV
95
1
$33.24
$15.19
Gas CO2
83 kg
EV CO2
28 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
Winston-Salem, NC
Morning
in Winston-Salem on Saturday
Local time
6:40 AM
EDT
Current temp
58°F
Partly Cloudy
SW 2 to 7 mph5% chanceLive forecast
Beach Hazards Statement
Beach Hazards Statement issued April 13 at 8:41PM EDT until April 14 at 8:00PM EDT by NWS Newport/Morehead City NC
Special Weather Statement
Special Weather Statement issued April 13 at 8:14PM EDT by NWS Greenville-Spartanburg SC
Destination
Saint James, NC
Morning
in Saint James on Saturday
Local time
6:40 AM
EDT
Current temp
56°F
Unavailable
Live forecast
57°F
Rockingham, NC
119 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 51m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Winston-Salem, NC to Saint James, NC covers 237.4 miles and takes about 4h 51m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 74, Andrew Jackson Highway, American Indian Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 118.7 miles from Winston-Salem, NC. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $37.12 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 237.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.5 miles: Multiple destination signs - pick the right one; at 0.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 3.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
The route from Winston-Salem, NC to Saint James, NC does not surface many named destination signs beyond the main corridor.
Yes. Nearby national parks include Moores Creek National Battlefield.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
