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Trip from Angier, NC to Winston-Salem, NC

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

2h 23m

Distance

113.7 mi

183 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$18

one way

EV Charging

Unknown

Best Time to Leave

Save up to 29 min
4 AM
2h 14m ★
6 AM
2h 23m
8 AM
2h 43m
10 AM
2h 30m
12 PM
2h 28m
3 PM
2h 31m
5 PM
2h 42m
8 PM
2h 17m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

human settlement in Harnett County, North Carolina, United States of America

Angier, NC

Wikimedia Commons

Trip Overview

The drive from Angier, NC to Winston-Salem, NC covers 113.7 miles and takes about 2h 23m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Isaac Brooks Highway, West Front Street, Salem Parkway for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 43.4 miles on Isaac Brooks Highway. At current regular gas prices, budget about $17.78 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Midpoint

56.8 miles from Angier, NC

A natural place for your longest stop of the day , about 1h 14m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 23m. Total distance: 113.7 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

2h 23m drive, comfortable solo distance.

Scenic Drive

Turn-heavy local drive route profile.

Drive Character

Expect a 2h 23m drive with frequent turns across 113.7 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 16 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Isaac Brooks Highway is the longest continuous segment at about 43.4 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 81.3 miles in near US 421.

Driving Effort 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 12 significant decision points across 113.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 81.3 miles (US 421): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 81.5 miles (US 421): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 87.2 miles (I 73; US 421 / Greensboro Urban Loop): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 12 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

8
81.3 mi into trip | ~1h 44m in | US 421

Take the exit onto US 421 toward I 85, US 421 North: Winston-Salem, Durham, Charlotte

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 197 Toward I 85, US 421 North: Winston-Salem, Durha...
8
81.5 mi into trip | ~1h 45m in | US 421

Keep slight left at fork onto US 421 toward I 85 South, US 421 North: Winston-Salem, Charlotte

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward I 85 South, US 421 North: Winston-Salem,...
9
87.2 mi into trip | ~1h 52m in | I 73; US 421 / Greensboro Urban Loop

Keep slight right at fork onto I 73; US 421 / Greensboro Urban Loop toward I 73 North, US 421 North: Winston-Salem, Martinsville

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Exit 121 Toward I 73 North, US 421 North: Winston-Salem,...
9
93.9 mi into trip | ~1h 59m in | US 421

Keep slight left at fork onto US 421 toward I 40 West, US 421 North: Winston-Salem

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Exit 103B Toward I 40 West, US 421 North: Winston-Salem
8
99.7 mi into trip | ~2h 6m in | US 421 / Salem Parkway

Keep slight right at fork onto US 421 / Salem Parkway toward US 421 North: Kernersville

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane. Exit 206 Toward US 421 North: Kernersville

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Angier, NC and Winston-Salem, NC, road signs point toward Durham, Charlotte and Martinsville.

Durham

81.3 mi in | ~1h 44m | via US 421

Charlotte

81.3 mi in | ~1h 44m | via US 421

Martinsville

87.2 mi in | ~1h 52m | via I 73; US 421

Main Roads

Road Distance Duration
Isaac Brooks Highway 43.4 mi 52m
West Front Street 17.3 mi 24m
Salem Parkway 13.4 mi 16m
Greensboro Urban Loop 11.5 mi 12m
Sanford Bypass 10.4 mi 11m
East Depot Street 8.8 mi 13m
US 421 7.3 mi 9m
South 10th Street 0.5 mi 1m
Longest stretch: Isaac Brooks Highway — 43.4 mi, about 52m

Turn-by-Turn Driving Directions

Step-by-step road directions between Angier, NC and Winston-Salem, NC.

1

Start on NC 210

8.8 mi · 13 min · East Depot Street
Use the left lane.
2

Turn right onto US 421 TRK

0.5 mi · 1 min · South 10th Street
3

Turn right onto US 421

17 mi · 24 min · West Front Street
Use the straight lane.
4

Take the ramp onto US 421

0.4 mi · 52 sec · US 421
Use the right lane.
5

Merge onto US 421; NC 87 BYP

10 mi · 11 min · Sanford Bypass
6

Continue on US 421

0.4 mi · 28 sec · Boone Trail Road
7

Continue on US 421

43 mi · 52 min · Isaac Brooks Highway
Use the straight / slight right lanes.
8

Take the exit onto US 421

0.2 mi · 27 sec · US 421
Exit 197 Toward I 85, US 421 North: Winston-Salem, Durham, Charlotte Use the slight right lane.
9

Keep slight left at fork onto US 421

0.8 mi · 1 min · US 421
Toward I 85 South, US 421 North: Winston-Salem, Charlotte Use the straight / slight right lanes.
10

Merge onto I 85; US 421

4.8 mi · 5 min · Greensboro Urban Loop
Use the straight / slight right lanes.
11

Keep slight right at fork onto I 73; US 421

6.7 mi · 7 min · Greensboro Urban Loop
Exit 121 Toward I 73 North, US 421 North: Winston-Salem, Martinsville Use the straight / slight right lanes.
12

Keep slight left at fork onto US 421

5.8 mi · 6 min · US 421
Exit 103B Toward I 40 West, US 421 North: Winston-Salem Use the slight left lane.
13

Keep slight right at fork onto US 421

13 mi · 16 min · Salem Parkway
Exit 206 Toward US 421 North: Kernersville Use the straight lane.
14

Take the exit

0.2 mi · 28 sec
Exit 233A Toward Main Street Use the slight right lane.
15

Turn slight right onto South Main Street

0.4 mi · 44 sec · South Main Street
Use the straight lane.
16

Arrive at destination

North Main Street

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 56.8 miles from Angier, NC, or about 1h 14m into the drive.
The longest continuous stretch on this route runs about 43.4 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 25 miles or 36m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 56.8 miles or 1h 14m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 58m

Traffic, exits, and arrival timing usually matter more near Winston-Salem, NC than in the middle of the route.

Before You Leave

+

Open the route before leaving Angier, NC so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Angier, NC

This is one driving day of about 113.7 miles and 2h 23m.

Your first comfortable stop window is around 25 miles from Angier, NC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Isaac Brooks Highway for about 43.4 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 56.8 mi from Angier, NC · 1h 14m into the drive

human settlement in Lee County, North Carolina, United States of America

Mid-route town

Meal stop

Sanford, NC

57 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Sanford, NC to Winston-Salem, NC

82.2 mi · 1h 41m

Pacing Suggestions

Sanford, NC

Fuel and coffee

A short stop after about 25 miles helps settle the day before fatigue starts building.

Sanford, NC

Meal break

The midpoint is around 56.8 miles from Angier, NC, which is a good place for a longer meal and fuel stop.

Arriving in Winston-Salem, NC

The final approach into Winston-Salem, NC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Winston-Salem, NC.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$17.78 one way

$35.56 round trip

$3.97/gal 25.4 MPG avg 40 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $19.44 $38.88
premium $4.70 $21.04 $42.09
diesel $5.61 $25.10 $50.21

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$18

Meals

$25–$50

Total

$43–$68

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 39.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $12 in charging · 0 stops · 68% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 34.1 0 $11.94 $5.46
Efficient EV 28.4 0 $9.95 $4.55
EV Truck/SUV 45.5 0 $15.92 $7.28

Gas CO2

40 kg

EV CO2

13 kg (68% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 18, 2026

Origin

Angier, NC

Late night in Angier on Saturday

Local time

2:15 AM

EDT

Current temp

49°F

Unavailable

Live forecast

Destination

Winston-Salem, NC

Late night in Winston-Salem on Saturday

Local time

2:15 AM

EDT

Current temp

61°F

Mostly Clear

N 1 to 5 mph 0% chance Live forecast

48°F

Sanford, NC

57 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

12 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 23m on the road

The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Angier, NC to Winston-Salem, NC covers 113.7 miles and takes about 2h 23m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Isaac Brooks Highway, West Front Street, Salem Parkway. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 56.8 miles from Angier, NC. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $17.78 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.

This is a demanding drive. With 12 significant decision points across 113.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

The main spots that need attention: at 81.3 miles (US 421): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 81.5 miles (US 421): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 87.2 miles (I 73; US 421 / Greensboro Urban Loop): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Between Angier, NC and Winston-Salem, NC, road signs point toward Durham, Charlotte and Martinsville.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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