Trip from Anna, TX to San Antonio, TX

Drive Time

5h 3m

Distance

340.9 mi

Route Type

Turn-heavy local drive

Long day trip

Trip Overview

The drive from Anna, TX to San Antonio, TX covers 340.9 miles and takes about 5h 3m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on West 4th Street, South Powell Parkway, McKinney Street for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $50.72 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

170.5 miles from Anna, TX

A natural place for your longest stop of the day.

Drive Character

Expect a 5h 3m drive with frequent turns across 340.9 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.

There are about 40 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

West 4th Street is one of the defining roads on this drive.

Main Roads

Road	Distance	Duration
West 4th Street	0 mi	0m
South Powell Parkway	0 mi	0m
McKinney Street	0 mi	0m
Sam Rayburn Highway	0 mi	0m
US 75 South	0 mi	0m
Central Expressway	0 mi	0m
Downtown	0 mi	0m
North Central Expressway	0 mi	0m

Longest stretch: West 4th Street — 0 mi, about 0m

Step-by-Step Directions

1

Start on South Sherley Road

2

Turn left onto West 4th Street

3

Turn left onto South Powell Parkway

4

Continue on McKinney Street

5

Turn right onto Sam Rayburn Highway

6

Keep slight left to continue on US 75 South, TX 121 South

7

Merge slight left onto Central Expressway

8

Take the exit slight left toward Downtown, Good-Latimer Expressway

9

Continue on North Central Expressway

10

Turn right onto Elm Street

11

Turn left onto North Pearl Expressway

12

Turn right onto Young Street

13

Turn left onto South Harwood Street

14

Turn right onto Canton Street

15

Take the ramp slight left toward I 30 West

16

Keep slight left to continue on I 35E South, I 35E North: Waco, Denton

17

Keep slight left to continue on I 35E North, I 35E South: Denton, Waco

18

Keep slight left to continue on I 35E South: Waco

19

Continue on South R L Thornton Freeway

20

Continue on South R L Thornton Freeway

21

Continue on North Jack Kultgen Expressway

22

Continue on Purple Heart Trail

23

Keep slight left

24

Keep slight left to continue on Purple Heart Trail

25

Continue on Interstate Highway 35

26

Continue on Purple Heart Trail

27

Continue on North Pan Am Expressway

28

Keep slight left to continue on North Pan Am Expressway

29

Keep slight left to continue on North Pan Am Expressway

30

Take the exit slight right toward Lexington Avenue, Main Avenue, San Pedro Avenue

31

Turn straight onto East Elmira Street

32

Turn left onto North Main Avenue

33

Enter the roundabout and take exit 2 toward Navarro Street

34

Exit the roundabout onto Navarro Street

35

Keep slight right to continue on North Main Avenue

36

Turn right onto West Travis Street

37

Turn left onto North Flores Street

38

Continue on Military Plaza

39

Turn left onto Dolorosa Street

40

Arrive at your destination

When to Leave

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 170.5 miles from Anna, TX.

This is a comfortable same-day trip.

Drive Plan

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 170.5 miles

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Last hour of driving

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Anna, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Trip Strategy

Day 1

Settle into the route from Anna, TX

This is one driving day of about 340.9 miles and 5h 3m.

Your first comfortable stop window is around 80 miles from Anna, TX.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

Best Stop Towns on This Route

These towns line up with the pace of this drive and give you clearer places to stop with a purpose.

Late stop town

Meal stop

Ames, TX

170 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Travel Advice

Arrival Notes

The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Stops Along the Way

Halfway Point

Midpoint

About 170.5 mi from Anna, TX

Addison, TX

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Ames, TX

Meal break

The midpoint is around 170.5 miles from Anna, TX, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Fuel Type	$/gal	One Way	Round Trip
regular	$3.78	$50.72	$101.44
midgrade	$4.25	$57.07	$114.13
premium	$4.59	$61.62	$123.23
diesel	$3.99	$53.59	$107.18

Based on 25.4 MPG average. Estimated CO2 emission: 119.3 kg one way.

Frequently Asked Questions

The drive from Anna, TX to San Antonio, TX covers 340.9 miles and takes about 5h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are West 4th Street, South Powell Parkway, McKinney Street. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 170.5 miles from Anna, TX. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $50.72 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.