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Trip from Anthony, TX to San Antonio, TX

Drive Time

9h 20m

Distance

572.2 mi

921 km

Drive Score

8/10

Great drive

Same Day?

2-day trip

Fuel Cost

$87

one way

Downtown San Antonio, TX, TX

San Antonio, TX

Wikimedia Commons

Trip Overview

Spanning 572.5 miles across the Texas landscape, this journey from Anthony to San Antonio takes approximately 8 hours and 28 minutes of pure driving time. Because of the significant distance, we recommend breaking this trip into two days to ensure you stay alert and enjoy the transition across the Great Plains. You should budget about $85 for fuel to cover the full trek. Relying on local routes like South 1st Street, Franklin Street, and Antonio Street rather than major interstates defines this path. It is a substantial commitment that requires careful pacing to avoid fatigue, making it better suited for an overnight itinerary than a single-day push.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

286.1 miles from Anthony, TX

A natural place for your longest stop of the day , about 4h 43m into the drive .

Drive Character

Expect a unique experience behind the wheel, as this route features 0% highway driving, relying instead on local roads that provide a different perspective of the Texas terrain. Navigating South 1st Street, Franklin Street, and Antonio Street means you will trade high-speed interstate monotony for a slower, more deliberate pace. The road's personality is defined by these local stretches, which demand your full attention and offer a steady rhythm rather than the quick, blurred vistas of a freeway. Since the entire journey stays within the Great Plains, you can anticipate consistent regional geography that unfolds gradually over your 8-hour and 28-minute travel time.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 16 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 10 is the longest continuous segment at about 555.7 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on I 10 and Camino Real de Tierra Adentro. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 188 miles in near I 10.

Route Complexity 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 11 significant decision points across 572.2 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 188 miles (I 10): Highway fork - watch signs carefully. Lane positioning matters here; at 551.4 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 568.9 miles (I 10; US 87 / McDermott Freeway): Highway fork - watch signs carefully. Lane positioning matters here.

Critical Maneuvers

5 of 11 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
188 mi into trip | ~3h 10m in | I 10

Keep slight right at fork onto I 10

Highway fork - watch signs carefully. Lane positioning matters here

Use the none / straight / slight right lanes.
6
551.4 mi into trip | ~8h 55m in | I 10; US 87

Keep slight right at fork onto I 10; US 87

Highway fork - watch signs carefully. Lane positioning matters here

Use the none lane.
6
568.9 mi into trip | ~9h 14m in | I 10; US 87 / McDermott Freeway

Keep slight right at fork onto I 10; US 87 / McDermott Freeway

Highway fork - watch signs carefully. Lane positioning matters here

Use the none lane.
8
570.5 mi into trip | ~9h 16m in

Take the exit toward Santa Rosa Street, Downtown

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 569C Toward Santa Rosa Street, Downtown
6
571.2 mi into trip | ~9h 18m in | North Pecos-La Trinidad

Keep slight right at fork onto North Pecos-La Trinidad

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane.

Main Roads

Road Distance Duration
I 10 555.7 mi 8h 57m
Camino Real de Tierra Adentro 11.6 mi 13m
McDermott Freeway 1.7 mi 2m
Franklin Street 0.8 mi 1m
North Pecos-La Trinidad 0.7 mi 1m
Antonio Street 0.5 mi 1m
Dolorosa Street 0.5 mi <1m
South 1st Street <0.1 mi <1m
Longest stretch: I 10 — 555.7 mi, about 8h 57m

Turn-by-Turn Driving Directions

Step-by-step road directions between Anthony, TX and San Antonio, TX.

1

Start on Jefferson Street

75 ft · 5 sec · Jefferson Street
2

Turn right onto South 1st Street

259 ft · 16 sec · South 1st Street
3

Turn left onto FM 1905

0.8 mi · 1 min · Franklin Street
4

Continue on FM 1905

0.5 mi · 1 min · Antonio Street
5

Turn right onto South Desert Boulevard

172 ft · 4 sec · South Desert Boulevard
6

Take the ramp

0.1 mi · 19 sec
7

Merge onto I 10; US 85; US 180

12 mi · 13 min · Camino Real de Tierra Adentro
Use the none / straight / slight right lanes.
8

Continue on I 10; US 180

175 mi · 2 hr 53 min · I 10; US 180
Use the none lane.
9

Keep slight right at fork onto I 10

363 mi · 5 hr 44 min · I 10
Use the none / straight / slight right lanes.
10

Keep slight right at fork onto I 10; US 87

17 mi · 19 min · I 10; US 87
Use the none lane.
11

Keep slight right at fork onto I 10; US 87

1.7 mi · 2 min · McDermott Freeway
Use the none lane.
12

Take the exit

0.5 mi · 1 min
Exit 569C Toward Santa Rosa Street, Downtown Use the slight right lane.
13

Turn straight onto North Pecos-La Trinidad

0.2 mi · 16 sec · North Pecos-La Trinidad
14

Keep slight right at fork onto North Pecos-La Trinidad

0.6 mi · 1 min · North Pecos-La Trinidad
Use the straight lane.
15

Turn left onto Dolorosa Street

0.5 mi · 55 sec · Dolorosa Street
Use the straight / left lanes.
16

Arrive at destination

Dolorosa Street

Trip Plan

To manage the 572.5-mile distance effectively, plan for at least two intentional stops to stretch your legs and refuel. Since you are navigating local roads rather than high-speed highways, account for potential fluctuations in travel time that might exceed the base estimate of 8 hours and 28 minutes. Setting aside $85 for gas is a solid baseline, but keeping a little extra in your travel budget is a smart move for longer stints. We suggest splitting the trip into two days to keep your arrival in San Antonio stress-free. A helpful tip for this specific route is to verify your navigation settings to ensure you remain on the designated local thoroughfares of South 1st, Franklin, and Antonio streets throughout the journey.

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 286.1 miles from Anthony, TX, or about 4h 43m into the drive.
The longest continuous stretch on this route runs about 555.7 miles.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 126 miles or 2h 8m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 286.1 miles or 4h 43m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 286.1 miles or 4h 43m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 8h 17m

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Anthony, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

+

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Anthony, TX

Aim for roughly 286 miles and 4.7 hours of wheel time on this day.

Day 2

Finish the approach into San Antonio, TX

Aim for roughly 286 miles and 4.7 hours of wheel time on this day.

Your first comfortable stop window is around 126 miles from Anthony, TX.
This route usually feels better as a 2-day drive than as one long push.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on I 10 for about 555.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 286.1 mi from Anthony, TX · 4h 43m into the drive

First major stop

Coffee and fuel

Fort Davis, TX

189 mi into the route

Best for: Coffee, fuel, and an easy first stretch

This is a natural early stop once the first hours of the drive are behind you.

Downtown Live Oak, TX, TX

Second major stop

Overnight candidate

Live Oak, TX

378 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Live Oak, TX

Overnight Options

Night 1

McCamey, TX

286 mi · about 4.7h in

A practical overnight split lands near McCamey, TX after about 286 miles or 4.7 hours of driving.

Find hotels

Pacing Suggestions

Fort Hancock, TX

Fuel and coffee

A short stop after about 126 miles helps settle the day before fatigue starts building.

McCamey, TX

Meal break

The midpoint is around 286.1 miles from Anthony, TX, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 10 if your tank is already low. That segment runs about 555.7 miles.

Overnight split

Hotel stop

For a steadier pace, wrap day one after about 286 miles or 4.7 hours on the road.

Arriving in San Antonio, TX

The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.

On a multi-day trip, keep the last day a little lighter so you reach San Antonio, TX with some flexibility left in the schedule.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$87.41 one way

$174.81 round trip

$3.88/gal 25.4 MPG avg 200 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $95.79 $191.57
premium $4.59 $103.42 $206.85
diesel $5.64 $127.12 $254.25

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$87

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$217–$327

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 200.2 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $60 in charging · 2 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 171.7 2 $60.08 $27.47
Efficient EV 143.1 1 $50.07 $22.89
EV Truck/SUV 228.9 2 $80.11 $36.62

Gas CO2

200 kg

EV CO2

67 kg (67% less)

Plan for 2 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 2 days ago

Origin

Anthony, TX

Afternoon in Anthony on Sunday

Local time

1:16 PM

MDT

Current temp

83°F

Unavailable

Live forecast

Destination

San Antonio, TX

Afternoon in San Antonio on Sunday

Local time

2:16 PM

CDT

Current temp

81°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

1 hour later

The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.

Temperature spread

2 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

9h 20m on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Anthony, TX to San Antonio, TX covers 572.2 miles and takes about 9h 20m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 10, Camino Real de Tierra Adentro, McDermott Freeway. Expect a mix of highway and local road driving.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 286 miles on day one.
The midpoint is about 286.1 miles from Anthony, TX. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $87.41 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 11 significant decision points across 572.2 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 188 miles (I 10): Highway fork - watch signs carefully. Lane positioning matters here; at 551.4 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 568.9 miles (I 10; US 87 / McDermott Freeway): Highway fork - watch signs carefully. Lane positioning matters here.
The route from Anthony, TX to San Antonio, TX does not surface many named destination signs beyond the main corridor.

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