Trip from Auburn, MS to Biloxi, MS

Data updated 0 seconds ago

Drive Time

6h 5m

Distance

311.1 mi

501 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$47

one way

EV Charging

station data

Best Time to Leave

Save up to 38 min

4 AM

5h 53m ★

6 AM

6h 6m

8 AM

6h 31m

10 AM

6h 15m

12 PM

6h 12m

3 PM

6h 16m

5 PM

6h 30m

8 PM

5h 58m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

Google Maps Waze Apple Maps

Download GPX

Auburn, MS

Dominik Gryzbon

Biloxi, MS

Wikimedia Commons

Trip Overview

The drive from Auburn, MS to Biloxi, MS covers 311.1 miles and takes about 6h 5m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on I 59, US Highway 45 Aiternate, US Highway 45 Alternate for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 88.7 miles on I 59. At current regular gas prices, budget about $46.98 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

155.6 miles from Auburn, MS

A natural place for your longest stop of the day , about 3h 6m into the drive .

Loading map...

Drive Character

This is a 6h 5m highway drive covering 311.1 miles, with most of the trip on I 59 and US Highway 45 Aiternate. The longest continuous stretch is about 88.7 miles on I 59.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.

There are about 30 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

I 59 is the longest continuous segment at about 88.7 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on I 59 and US Highway 45 Aiternate. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 6.2 miles in.

Route Complexity 9/10

High effort - long or complex enough to need steady focus all day

This is a demanding drive. With 15 significant decision points across 311.1 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 6.2 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 151 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 239.7 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 15 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6.2 mi into trip | ~11m in

Turn left toward US 45 South, MS 6 West: Columbus, Pontotoc

Lane positioning matters here. Multiple destination signs - pick the right one

Use the left lane. Toward US 45 South, MS 6 West: Columbus, Pontot...

151 mi into trip | ~3h 1m in | I 59

Keep slight left at fork onto I 59 toward I 59 South: Laurel, New Orleans

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left / slight right lanes. Toward I 59 South: Laurel, New Orleans

239.7 mi into trip | ~4h 37m in | US 98

Take the exit onto US 98 toward US 98 East: Lucedale, Mobile

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 98 East: Lucedale, Mobile

242.9 mi into trip | ~4h 41m in

Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 49: Wiggins, Gulfport, Mississippi Gu...

243.2 mi into trip | ~4h 42m in

Keep slight left at fork toward Multi Purpose Center, Hattiesburg

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left / slight right lanes. Toward Multi Purpose Center, Hattiesburg

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Auburn, MS and Biloxi, MS, road signs point toward New Orleans, Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.

New Orleans

151 mi in | ~3h 1m | via I 59

Mobile

239.7 mi in | ~4h 37m | via US 98

Gulfport

242.9 mi in | ~4h 41m

Mississippi Gulf Coast

242.9 mi in | ~4h 41m

Multi Purpose Center

243.2 mi in | ~4h 42m

Hattiesburg

243.2 mi in | ~4h 42m

Main Roads

Road	Distance	Duration
I 59	88.7 mi	1h 36m
US Highway 45 Aiternate	60.6 mi	1h 9m
US Highway 45 Alternate	54.7 mi	1h 6m
US 49	41.9 mi	49m
Biloxi-D'Iberville Scenic Expressway	20.5 mi	24m
I 20	8.1 mi	9m
Martin Luther King Drive	7.7 mi	8m
US 45 ALT	7.2 mi	8m

Longest stretch: I 59 — 88.7 mi, about 1h 36m

Turn-by-Turn Driving Directions

Step-by-step road directions between Auburn, MS and Biloxi, MS.

Start on County Road 1438

119 ft · 10 sec · County Road 1438

Turn left onto CR 931

1.1 mi · 2 min · Auburn Road / County Road 931

Continue on North Eason Boulevard

5.1 mi · 8 min · North Eason Boulevard

Use the straight lane.

Turn left

0.3 mi · 33 sec

Toward US 45 South, MS 6 West: Columbus, Pontotoc Use the left lane.

Merge onto US 45; MS 6

1.9 mi · 2 min · Martin Luther King, Junior Drive

Continue on US 45; US 278

7.7 mi · 8 min · Martin Luther King Drive

Continue on US 45 ALT

1.4 mi · 1 min · US 45 ALT

Continue on US 45 ALT

2.2 mi · 2 min · US 45 ALT

Continue on US 45 ALT

1.5 mi · 1 min · US 45 ALT

Continue on US 45 ALT

0.7 mi · 49 sec · US 45 ALT

Continue on US 45 ALT

1.4 mi · 1 min · US 45 ALT

Continue on US 45 ALT

55 mi · 1 hr 6 min · US Highway 45 Alternate

Use the straight lane.

Continue on US 45

61 mi · 1 hr 9 min · US Highway 45 Aiternate

Keep slight right at fork onto US 45

3.9 mi · 4 min · US 45

Take the exit

0.5 mi · 1 min

Toward I 59 South, I 20 West: Meridian

Merge onto I 20; I 59

6.3 mi · 7 min · I 20; I 59

Use the straight / slight right lanes.

Continue on I 20; I 59; US 80

1.8 mi · 2 min · I 20; I 59; US 80

Use the straight lane.

Keep slight left at fork onto I 59

89 mi · 1 hr 36 min · I 59

Toward I 59 South: Laurel, New Orleans Use the slight left / slight right lanes.

Take the exit onto US 98

3.2 mi · 4 min · US 98

Toward US 98 East: Lucedale, Mobile Use the straight / slight right lanes.

Take the exit

0.3 mi · 44 sec

Toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast Use the straight / slight right lanes.

Keep slight left at fork

0.2 mi · 27 sec

Toward Multi Purpose Center, Hattiesburg Use the slight left / slight right lanes.

Turn right onto US 49

42 mi · 49 min · US 49

Use the straight lane.

Take the exit

0.8 mi · 1 min

Toward MS 67 South: D'Iberville, Biloxi

Continue on MS 67

20 mi · 24 min · Biloxi-D'Iberville Scenic Expressway

Continue on I 110

3.2 mi · 4 min · I 110

Take the exit

0.4 mi · 47 sec

Exit 1c Toward Division Street

Turn left onto Division Street

0.6 mi · 1 min · Division Street

Turn right onto Main Street

0.5 mi · 1 min · Main Street

Turn left onto Howard Avenue

91 ft · 3 sec · Howard Avenue

Arrive at destination

Howard Avenue

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 155.6 miles from Auburn, MS, or about 3h 6m into the drive.

The longest continuous stretch on this route runs about 88.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 39m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 155.6 miles or 3h 6m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 56m

Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.

Before You Leave

Open the route before leaving Auburn, MS so your first major turns are already loaded.

Leave with enough water and a charging cable within reach, not packed away.

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Auburn, MS

This is one driving day of about 311.1 miles and 6h 5m.

Your first comfortable stop window is around 80 miles from Auburn, MS.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

The longest stretch is on I 59 for about 88.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 155.6 mi from Auburn, MS · 3h 6m into the drive

Mid-route town

Meal stop

Butler, AL

156 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Butler, AL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Butler, AL

Meal break

The midpoint is around 155.6 miles from Auburn, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 59 if your tank is already low. That segment runs about 88.7 miles.

Arriving in Biloxi, MS

The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$46.98 one way

$93.97 round trip

$3.84/gal 25.4 MPG avg 109 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.21	$51.58	$103.15
premium	$4.56	$55.84	$111.68
diesel	$5.61	$68.69	$137.37

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$47

Meals

$25–$50

Total

$72–$97

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 108.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $33 in charging · 1 stop · 67% less CO₂

Vehicle Type	kWh	Stops	DC Fast	Home Charge
Average EV	93.3	1	$32.67	$14.93
Efficient EV	77.8	0	$27.22	$12.44
EV Truck/SUV	124.4	1	$43.55	$19.91

Gas CO2

109 kg

EV CO2

36 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 2 hours ago

Origin

Auburn, MS

Late night in Auburn on Wednesday

Local time

5:27 AM

CDT

Current temp

78°F

Unavailable

Live forecast

Destination

Biloxi, MS

Late night in Biloxi on Wednesday

Local time

5:27 AM

CDT

Current temp

69°F

Unavailable

Live forecast

48°F

Butler, AL

156 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

9 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 5m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Auburn, MS to Biloxi, MS covers 311.1 miles and takes about 6h 5m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are I 59, US Highway 45 Aiternate, US Highway 45 Alternate. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 155.6 miles from Auburn, MS. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $46.98 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Between Auburn, MS and Biloxi, MS, road signs point toward New Orleans, Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.

Was this route helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Explore more options from Auburn, MS or browse trips ending in Biloxi, MS.

Looking for more statewide routes? Browse MS road trips.

Explore maps for Auburn, MS or Biloxi, MS on MapSof.net.

Trip from Auburn, MS to Biloxi, MS

Best Time to Leave

Trip Overview

Drive Character

How Hard Is This Drive?

Critical Maneuvers

Towns Mentioned on Route Signs

Main Roads

Turn-by-Turn Driving Directions

Trip Plan

Before You Leave

Where to Stop

Pacing Suggestions

Arriving in Biloxi, MS

Fuel & Cost

Travel Intel

Auburn, MS

Biloxi, MS

Same local time

9 degrees cooler at arrival

6h 5m on the road

Frequently Asked Questions

Was this route helpful?

Explore More

Continue From Biloxi, MS

More from Auburn, MS

More trips to Biloxi, MS