Drive Time
4h 26m
Distance
230.2 mi
371 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$35
one way
Photo: 大 董
If you are planning a trip from Carthage to Biloxi, expect a straightforward journey covering 230.2 miles. You can easily complete this drive in about 4 hours and 26 minutes, making it a manageable day trip that does not require an overnight stay. Your path primarily utilizes the Stephen E Ambrose Memorial Parkway, West Florida Republic Parkway, and I-55 to get you from the interior of Mississippi to the coast. Budget approximately $35 for fuel to cover the distance. Since both the origin and destination are located within the Southeast, you will experience a consistent regional feel throughout your transit. It is a practical, efficient route for travelers looking to reach the Gulf Coast without unnecessary detours.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
115.1 miles from Carthage, MS
A natural place for your longest stop of the day , about 2h 18m into the drive .
This trip is heavily highway-focused, with 94% of your time spent on major roads. You will find that the rhythm of the drive is consistent, characterized by long, open stretches that help you cover ground quickly. The longest uninterrupted portion occurs early on, spanning 51.2 miles along the Stephen E Ambrose Memorial Parkway. While you won't encounter significant technical terrain, the transition from inland Mississippi toward the coastal region keeps the drive moving at a steady pace. Expect a reliable, predictable experience behind the wheel rather than a winding backroad adventure.
This is a straightforward highway drive that stays mostly on Stephen E Ambrose Memorial Parkway and West Florida Republic Parkway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 39.1 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 18 significant decision points across 230.2 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 39.1 miles: Highway fork - watch signs carefully; at 125.5 miles: Exit ramp - move to the correct lane early; at 125.7 miles (I 12 / West Florida Republic Parkway): Merge point - match speed before joining. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight left at fork
Highway fork - watch signs carefully
Take the exit toward I 12 East: Slidell
Exit ramp - move to the correct lane early
Merge onto I 12 / West Florida Republic Parkway
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight right at fork toward I 110: Biloxi, Keesler Air Force Base
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
| Road | Distance | Duration |
|---|---|---|
| Stephen E Ambrose Memorial Parkway | 51.2 mi | 54m |
| West Florida Republic Parkway | 48.2 mi | 51m |
| I 55 | 43.2 mi | 46m |
| US 98 | 43.2 mi | 48m |
| US 84 | 28.3 mi | 32m |
| Seargent Prentiss Drive | 6.4 mi | 7m |
| I 110 | 2.7 mi | 3m |
| Carthage Point Road | 2.3 mi | 8m |
Step-by-step road directions between Carthage, MS and Biloxi, MS.
Start on this road
Turn straight onto Carthage Point Road
Keep slight left at fork onto Carthage Point Road
Turn straight onto Lower Woodville Road
Turn right onto Highland Boulevard
Turn left onto US 61
Take the exit onto US 84
Take the exit
Keep slight left at fork
Turn right onto US 98; MS 184
Turn right onto US 98
Take the exit onto US 98
Continue on I 55
Take the exit
Merge onto I 12
Continue on I 12
Merge onto I 10
Take the exit
Keep slight left at fork
Keep slight right at fork
Merge onto I 110
Take the exit
Turn left onto Division Street
Turn right onto Main Street
Turn left onto Howard Avenue
Arrive at destination
To keep your travel stress-free, plan for at least one dedicated stop during your 230.2-mile trek to break up the monotony of the highway. Because the drive is under five hours, you have the flexibility to depart at a time that best fits your schedule, though leaving early morning can help you avoid potential traffic closer to the coast. Keep a close eye on your fuel gauge, keeping that $35 budget in mind as you navigate the interstate sections. Since the route is dominated by high-speed roads, ensure your vehicle is prepped for sustained highway driving. Taking your single break midway through the journey will help you arrive in Biloxi feeling refreshed and ready for the coast.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 40m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 115.1 miles or 2h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 37m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Open the route before leaving Carthage, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Carthage, MS
This is one driving day of about 230.2 miles and 4h 26m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 115.1 mi from Carthage, MS · 2h 18m into the drive
Mid-route town
Meal stop
115 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 115.1 miles from Carthage, MS, which is a good place for a longer meal and fuel stop.
The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$35.19 one way
$70.38 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $38.60 | $77.20 |
| premium | $4.61 | $41.78 | $83.56 |
| diesel | $5.64 | $51.14 | $102.28 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 80.5 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $24 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 69.1 | 0 | $24.17 | $11.05 |
| Efficient EV | 57.6 | 0 | $20.14 | $9.21 |
| EV Truck/SUV | 92.1 | 1 | $32.23 | $14.73 |
Gas CO2
81 kg
EV CO2
27 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Carthage on Sunday
Local time
3:56 AM
CDT
Current temp
66°F
Forecast unavailable right now
Destination
Late night in Biloxi on Sunday
Local time
3:56 AM
CDT
Current temp
69°F
Forecast unavailable right now
Along the Route
88°F
Central, LA
115 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
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