Trip from Carthage, TX to San Antonio, TX
Drive Time
5h 55m
Distance
354.5 mi
Route Type
Turn-heavy local drive
Long day tripTrip Overview
The drive from Carthage, TX to San Antonio, TX covers 354.5 miles and takes about 5h 55m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on North Saint Mary Street, West Sabine Street, North Railroad Avenue for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $52.74 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
177.3 miles from Carthage, TX
A natural place for your longest stop of the day.
Drive Character
Expect a 5h 55m drive with frequent turns across 354.5 miles of local and secondary roads.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| North Saint Mary Street | 0 mi | 0m |
| West Sabine Street | 0 mi | 0m |
| North Railroad Avenue | 0 mi | 0m |
| Route 259 | 0 mi | 0m |
| Highway 259 | 0 mi | 0m |
| US 59 South | 0 mi | 0m |
| Highway 59 | 0 mi | 0m |
| Northwest Stallings Drive | 0 mi | 0m |
Step-by-Step Directions
Start on Panola Street
Turn left onto North Saint Mary Street
Turn right onto West Sabine Street
Continue straight
At the end of the road, turn left onto North Railroad Avenue
Continue on US Route 259
Continue on US Highway 259
Take the exit slight right toward US 59 South: Lufkin
Continue straight
Continue straight
Turn left
Turn right onto North US Highway 59
Continue on Northwest Stallings Drive
Take the exit slight right
Turn right onto South Fredonia Street
Continue on West State Highway 7
Turn right onto 5th Street
Turn left onto East Houston Avenue
Turn left onto South 4th Street
Turn right onto East Goliad Avenue
Turn left
Turn left onto State Highway 95
Turn right onto State Highway 71 East
Take the ramp slight left toward TX 21 West, TX 71 West
Merge slight left onto State Highway 71 East
Continue straight
Continue straight
Take the exit slight right toward TX 21 West: San Marcos
Turn left onto West State Highway 21
Turn left onto US 183, Toll 130 South
Turn straight
Take the ramp slight left toward TX 130 Toll South
Merge slight left onto Pickle Parkway
Keep slight right to continue on I 10 West: San Antonio
Merge slight left
Continue straight
Keep slight left
Keep slight left to continue on 90th Infantry Division Highway
Continue on Jose Lopez Freeway
Take the exit slight right toward Commerce Street, Houston Street
Turn straight onto Interstate 10 East
Turn right onto East Houston Street
Turn slight left onto East Commerce Street
Turn left onto Military Plaza
Turn left onto Dolorosa Street
Arrive at your destination
When to Leave
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Drive Plan
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 177.3 miles
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Last hour of driving
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Before You Leave
Open the route before leaving Carthage, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Trip Strategy
Day 1
Settle into the route from Carthage, TX
This is one driving day of about 354.5 miles and 5h 55m.
Best Stop Towns on This Route
These towns line up with the pace of this drive and give you clearer places to stop with a purpose.
Late stop town
Meal stop
177 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Travel Advice
Arrival Notes
Seasonal Notes
Stops Along the Way
Halfway Point
Midpoint
About 177.3 mi from Carthage, TX
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 177.3 miles from Carthage, TX, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| regular | $3.78 | $52.74 | $105.48 |
| midgrade | $4.25 | $59.34 | $118.69 |
| premium | $4.59 | $64.08 | $128.15 |
| diesel | $3.99 | $55.73 | $111.46 |
Based on 25.4 MPG average. Estimated CO2 emission: 124 kg one way.
Frequently Asked Questions
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Next Route Ideas
Reverse Route
San Antonio, TX to Carthage, TXUseful if you are planning the return drive and want the same trip in reverse.
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