Trip from East Independence, MO to Murphy, MO

Data updated 4 hours ago

Drive Time

4h 37m

Distance

233.4 mi

376 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$36

one way

EV Charging

None

0 DC fast

Best Time to Leave

Save up to 40 min

4 AM

4h 24m ★

6 AM

4h 37m

8 AM

5h 4m

10 AM

4h 47m

12 PM

4h 44m

3 PM

4h 48m

5 PM

5h 3m

8 PM

4h 29m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

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East Independence, MO

Momo King

Murphy, MO

Valeria Boltneva

Trip Overview

The drive from East Independence, MO to Murphy, MO covers 233.4 miles and takes about 4h 37m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Avenue of the Saints for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 135.3 miles on Dwight D. Eisenhower Highway. At current regular gas prices, budget about $36.49 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

116.7 miles from East Independence, MO

A natural place for your longest stop of the day , about 2h 12m into the drive .

Loading map...

Drive Character

Expect a 4h 37m drive with frequent turns across 233.4 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.

There are about 27 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

Dwight D. Eisenhower Highway is the longest continuous segment at about 135.3 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 16 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near Main Road.

Route Complexity 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

This drive requires moderate attention. Across 233.4 miles you will encounter 16 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: near the start (Main Road): Navigation decision point; at 5 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 198.5 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 16 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

0 mi into trip | ~0m in | Main Road

Turn left onto Main Road

Navigation decision point

5 mi into trip | ~10m in

Take the ramp toward Little Blue Parkway, 39th Street, Mall Entrance

Lane positioning matters here. Multiple destination signs - pick the right one

Use the left lane. Exit 17 Toward Little Blue Parkway, 39th Street, Mall E...

198.5 mi into trip | ~3h 48m in | US 40

Take the exit onto US 40 toward I 64 East, US 40 East, US 61 South: Chesterfield

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 210A Toward I 64 East, US 40 East, US 61 South: Ches...

198.8 mi into trip | ~3h 49m in | I 64; US 40; US 61 / Avenue of the Saints

Merge onto I 64; US 40; US 61 / Avenue of the Saints

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight left lanes.

220.8 mi into trip | ~4h 15m in

Take the exit toward MO 141

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 22 Toward MO 141

Main Roads

Road	Distance	Duration
Dwight D. Eisenhower Highway	135.3 mi	2h 34m
U.S. Submarine Veterans' Memorial Highway	54.4 mi	58m
Avenue of the Saints	22 mi	26m
MO 141	8.5 mi	13m
Sheriff Roger I. Wilson Memorial Highway	1.9 mi	2m
South Little Blue Parkway	1.7 mi	3m
Hawkins Road	1.6 mi	3m
Highway Patrol Sgt. Benjamin Booth Memorial Highway	1.6 mi	1m

Longest stretch: Dwight D. Eisenhower Highway — 135.3 mi, about 2h 34m

Turn-by-Turn Driving Directions

Step-by-step road directions between East Independence, MO and Murphy, MO.

Start on East 9th Street South

79 ft · 8 sec · East 9th Street South

Turn left onto Main Road

0.3 mi · 1 min · Main Road

Turn left onto East Truman Road

0.7 mi · 1 min · East Truman Road

Turn right onto Holke Road

0.9 mi · 1 min · Holke Road

Turn straight onto South Jackson Drive

1.2 mi · 2 min · South Jackson Drive

Turn left onto East R.D. Mize Road

0.2 mi · 37 sec · East R.D. Mize Road

Turn right onto South Little Blue Parkway

1.7 mi · 3 min · South Little Blue Parkway

Take the ramp

0.3 mi · 38 sec

Exit 17 Toward Little Blue Parkway, 39th Street, Mall Entrance Use the left lane.

Continue on I 70

53 mi · 56 min · Dwight D. Eisenhower Highway

Continue on I 70; US 40

32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway

Keep slight left at fork onto I 70

22 mi · 24 min · U.S. Submarine Veterans' Memorial Highway

Continue on I 70; US 40

1.8 mi · 2 min · Dwight D. Eisenhower Highway

Continue on I 70; US 40

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway

Continue on I 70; US 40

1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway

Continue on I 70; US 40

81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway

Take the exit onto US 40

0.3 mi · 33 sec · US 40

Exit 210A Toward I 64 East, US 40 East, US 61 South: Chesterfield

Merge onto I 64; US 40; US 61

22 mi · 26 min · Avenue of the Saints

Use the straight / slight left lanes.

Take the exit

0.3 mi · 33 sec

Exit 22 Toward MO 141 Use the slight right lane.

Turn right

185 ft · 5 sec

Toward MO 141: Manchester

Merge onto MO 141

8.5 mi · 13 min · MO 141

Use the right lane.

Turn right onto Hawkins Road

1.6 mi · 3 min · Hawkins Road

Continue on New Sugar Creek Road

1.0 mi · 2 min · New Sugar Creek Road

Turn left onto Gravois Road

0.5 mi · 57 sec · Gravois Road

Turn right onto Valley Dell Drive

31 ft · 1 sec · Valley Dell Drive

Turn right onto MO 30

0.5 mi · 43 sec · MO 30

Turn right

35 ft · 0 sec

Toward New Sugar Creek Road

Arrive at destination

Toward New Sugar Creek Road

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 116.7 miles from East Independence, MO, or about 2h 12m into the drive.

The longest continuous stretch on this route runs about 135.3 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 32m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 116.7 miles or 2h 12m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 40m

Traffic, exits, and arrival timing usually matter more near Murphy, MO than in the middle of the route.

Before You Leave

Open the route before leaving East Independence, MO so your first major turns are already loaded.

Leave with enough water and a charging cable within reach, not packed away.

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from East Independence, MO

This is one driving day of about 233.4 miles and 4h 37m.

Your first comfortable stop window is around 80 miles from East Independence, MO.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

The longest stretch is on Dwight D. Eisenhower Highway for about 135.3 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 116.7 mi from East Independence, MO · 2h 12m into the drive

Mid-route town

Meal stop

Quincy, IL

117 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Kansas City, MO

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Quincy, IL

Meal break

The midpoint is around 116.7 miles from East Independence, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 135.3 miles.

Arriving in Murphy, MO

The final approach into Murphy, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Murphy, MO.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

17 mi from route ~43 min detour $19 near mile 225.3

View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$36.49 one way

$72.98 round trip

$3.97/gal 25.4 MPG avg 82 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.36	$40.06	$80.13
premium	$4.89	$44.92	$89.83
diesel	$5.61	$51.53	$103.06

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$36

Meals

$25–$50

Total

$61–$86

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 81.7 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $25 in charging · 0 stops · 67% less CO₂

Vehicle Type	kWh	Stops	DC Fast	Home Charge
Average EV	70	0	$24.51	$11.20
Efficient EV	58.4	0	$20.42	$9.34
EV Truck/SUV	93.4	1	$32.68	$14.94

Gas CO2

82 kg

EV CO2

27 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 5 days ago

Origin

East Independence, MO

Night in East Independence on Tuesday

Local time

10:56 PM

CDT

Current temp

49°F

Unavailable

Live forecast

Destination

Murphy, MO

Night in Murphy on Tuesday

Local time

10:56 PM

CDT

Current temp

45°F

Unavailable

Live forecast

55°F

Quincy, IL

117 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

4 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 37m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from East Independence, MO to Murphy, MO covers 233.4 miles and takes about 4h 37m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Avenue of the Saints. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 116.7 miles from East Independence, MO. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $36.49 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

The route from East Independence, MO to Murphy, MO does not surface many named destination signs beyond the main corridor.

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