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Trip from East Independence, MO to Potosi, MO

Last recalculated Apr 16, 2026

Drive Time

5h 25m

Distance

259.3 mi

417 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$41

one way

Best Time to Leave

Save up to 41 min
4 AM
5h 12m ★
6 AM
5h 26m
8 AM
5h 53m
10 AM
5h 35m
12 PM
5h 32m
3 PM
5h 36m
5 PM
5h 51m
8 PM
5h 18m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown East Independence, MO, MO

East Independence, MO

Momo King

Trip Overview

The drive from East Independence, MO to Potosi, MO covers 259.3 miles and takes about 5h 25m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Main Road, East Truman Road, Holke Road for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $40.54 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

129.6 miles from East Independence, MO

A natural place for your longest stop of the day , about 2h 42m into the drive .

Drive Character

Expect a 5h 25m drive with frequent turns across 259.3 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 26 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Main Road is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Route Complexity 3/10

Easy - simple navigation with a manageable amount of wheel time

This is a straightforward 5h 25m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from East Independence, MO to Potosi, MO is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
Main Road
East Truman Road
Holke Road
South Jackson Drive
East R
South Little Blue Parkway
Little Blue Parkway
Dwight D

Some road-level metrics are being recalculated.

Longest stretch: Main Road — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between East Independence, MO and Potosi, MO.

1

Start on East 9th Street South

79 ft · 9 sec · East 9th Street South
2

Turn left onto Main Road

0.3 mi · 1 min · Main Road
3

Turn left onto East Truman Road

0.7 mi · 1 min · East Truman Road
4

Turn right onto Holke Road

0.9 mi · 1 min · Holke Road
5

Turn straight onto South Jackson Drive

1.2 mi · 2 min · South Jackson Drive
6

Turn left onto East R.D. Mize Road

0.2 mi · 37 sec · East R.D. Mize Road
7

Turn right onto South Little Blue Parkway

1.7 mi · 3 min · South Little Blue Parkway
8

Take the ramp left toward Little Blue Parkway, 39th Street, Mall Entrance

0.3 mi · 38 sec · Little Blue Parkway, 39th Street, Mall Entrance
9

Continue on Dwight D. Eisenhower Highway

53 mi · 56 min · Dwight D. Eisenhower Highway
10

Continue on U.S. Submarine Veterans' Memorial Highway

32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
11

Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway

22 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
12

Continue on Dwight D. Eisenhower Highway

1.8 mi · 2 min · Dwight D. Eisenhower Highway
13

Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
14

Continue on Sheriff Roger I. Wilson Memorial Highway

1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
15

Continue on Dwight D. Eisenhower Highway

64 mi · 1 hr 12 min · Dwight D. Eisenhower Highway
16

Take the exit slight right toward MO 47: Warrenton, Hawk Point

0.2 mi · 19 sec · MO 47: Warrenton, Hawk Point
17

Turn right

31 mi · 47 min
18

At the end of the road, turn left

0.4 mi · 50 sec
19

Take the exit right

138 ft · 5 sec
20

Turn right

6.2 mi · 8 min
21

Turn right onto Commercial Avenue

1.0 mi · 1 min · Commercial Avenue
22

Continue on East Gravois Avenue

6.2 mi · 9 min · East Gravois Avenue
23

Turn right

20 mi · 34 min
24

At the end of the road, turn right

11 mi · 15 min
25

Turn right onto East High Street

1.0 mi · 1 min · East High Street
26

Arrive at your destination

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 129.6 miles from East Independence, MO, or about 2h 42m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 57 miles or 1h 11m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 129.6 miles or 2h 42m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 27m

Traffic, exits, and arrival timing usually matter more near Potosi, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving East Independence, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from East Independence, MO

This is one driving day of about 259.3 miles and 5h 25m.

Your first comfortable stop window is around 57 miles from East Independence, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 129.6 mi from East Independence, MO · 2h 42m into the drive

Downtown O'Fallon, MO, MO

Mid-route town

Meal stop

O'Fallon, MO

130 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Warrensburg, MO

Fuel and coffee

A short stop after about 57 miles helps settle the day before fatigue starts building.

O'Fallon, MO

Meal break

The midpoint is around 129.6 miles from East Independence, MO, which is a good place for a longer meal and fuel stop.

Arriving in Potosi, MO

The final approach into Potosi, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Potosi, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$40.54 one way

$81.08 round trip

$3.97/gal 25.4 MPG avg 91 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $44.51 $89.02
premium $4.89 $49.90 $99.80
diesel $5.61 $57.25 $114.50

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$41

Meals

$25–$50

Total

$66–$91

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 90.7 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $27 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 77.8 0 $27.23 $12.45
Efficient EV 64.8 0 $22.69 $10.37
EV Truck/SUV 103.7 1 $36.30 $16.60

Gas CO2

91 kg

EV CO2

30 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

East Independence, MO

Evening in East Independence on Wednesday

Local time

7:47 PM

CDT

Current temp

56°F

Unavailable

Live forecast

Destination

Potosi, MO

Evening in Potosi on Wednesday

Local time

7:47 PM

CDT

Current temp

56°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

Very similar conditions

Both ends of the route are sitting at about the same temperature right now.

Road read

5h 25m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from East Independence, MO to Potosi, MO covers 259.3 miles and takes about 5h 25m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Main Road, East Truman Road, Holke Road. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 129.6 miles from East Independence, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $40.54 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a straightforward 5h 25m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
This route does not have any notably tricky sections. Most of the drive from East Independence, MO to Potosi, MO is straightforward, with well-signed roads and simple exits.
The route from East Independence, MO to Potosi, MO does not surface many named destination signs beyond the main corridor.

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