The drive from Edwards, MS to Tupelo, MS covers 222.8 miles and takes about 4h 22m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on MS Hwy 25, MS 25, US Highway 45 Alternate for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 79.6 miles on MS Hwy 25.
At current regular gas prices, budget about $33.65 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
111.4 miles from Edwards, MS
A natural place for your longest stop of the day
, about 2h 9m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 22m. Total distance: 222.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 22m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (85%). Some complex stretches to watch for.
Drive Character
This is a 4h 22m highway drive covering 222.8 miles, with most of the trip on MS Hwy 25 and MS 25. The longest continuous stretch is about 79.6 miles on MS Hwy 25.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 25 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MS Hwy 25 is the longest continuous segment at about 79.6 miles.
Elevation Profile
Mostly flat terrain
538 ft215 ft
Total Climb
470 ft
Total Descent
417 ft
Highest Point
538 ft
~111.4 mi in
Elevation Range
324 ft
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on MS Hwy 25 and MS 25. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive near South Main Street.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 222.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: near the start (South Main Street): Navigation decision point; at 0.1 miles (MS 467 / Vicksburg Street): Navigation decision point; at 27.4 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 16 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0 mi into trip|~0m in|South Main Street
Turn left onto South Main Street
Navigation decision point
5
0.1 mi into trip|~0m in|MS 467 / Vicksburg Street
Turn right onto MS 467 / Vicksburg Street
Navigation decision point
6
27.4 mi into trip|~32m in|I 55
Keep slight left at fork onto I 55 toward Grenada, Memphis
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Grenada, Memphis
6
148.7 mi into trip|~2h 52m in|MS 25
Keep slight right at fork onto MS 25
Highway fork - watch signs carefully. Lane positioning matters here
Use the left lane.
6
154.9 mi into trip|~2h 59m in|MS 25
Keep slight right at fork onto MS 25 toward US 82 East, MS 25 North: Columbus, West Point
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 82 East, MS 25 North: Columbus, West...
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Edwards, MS and Tupelo, MS, road signs point toward Grenada, Memphis and Point.
Grenada
27.4 mi in|~32m|via I 55
Memphis
27.4 mi in|~32m|via I 55
Point
154.9 mi in|~2h 59m|via MS 25
Main Roads
Road
Distance
Duration
MS Hwy 25
79.6 mi
1h 30m
MS 25
43.5 mi
50m
US Highway 45 Alternate
34.6 mi
42m
I 20
26.2 mi
30m
Martin Luther King Drive
18.1 mi
20m
Lakeland Drive
12.3 mi
14m
I 55
4.2 mi
5m
Martin Luther King, Junior Drive
1.5 mi
2m
Longest stretch:
MS Hwy 25
— 79.6 mi, about 1h 30m
Turn-by-Turn Driving Directions
Step-by-step road directions between Edwards, MS and Tupelo, MS.
1
Start on Pine Street
43 ft·7 sec·Pine Street
2
Turn left onto South Main Street
324 ft·16 sec·South Main Street
3
Turn right onto MS 467
0.1 mi·11 sec·Vicksburg Street
4
Turn straight onto MS 467
0.7 mi·1 min·Jackson Street
5
Continue on MS 467
389 ft·6 sec·Jackson Street
6
Take the ramp
0.3 mi·32 sec
7
Merge onto I 20; US 80
25 mi·28 min·I 20; US 80
8
Merge onto I 20; I 55; US 49
1.1 mi·1 min·I 20; I 55; US 49
9
Keep slight left at fork onto I 55
4.2 mi·5 min·I 55
Toward Grenada, Memphis
10
Take the exit
0.2 mi·27 sec
Toward MS 25 North: Carthage
11
Turn right onto MS 25
12 mi·14 min·Lakeland Drive
12
Continue on MS 25
80 mi·1 hr 30 min·MS Hwy 25
13
Take the exit onto MS 25
25 mi·29 min·MS 25
14
Keep slight right at fork onto MS 25
2.4 mi·2 min·MS 25
Use the left lane.
15
Continue on MS 25
3.8 mi·4 min·MS 25
16
Keep slight right at fork onto MS 25
12 mi·13 min·MS 25
Toward US 82 East, MS 25 North: Columbus, West Point
17
Take the exit
0.3 mi·34 sec
Toward US 45 Alternate North, MS 25 North: West Point, Tupelo
18
Merge onto US 45 ALT; MS 25
35 mi·42 min·US Highway 45 Alternate
Use the straight lane.
19
Continue on US 45 ALT
18 mi·20 min·Martin Luther King Drive
20
Continue on US 45; MS 6
1.5 mi·2 min·Martin Luther King, Junior Drive
21
Take the exit onto MS 6
0.4 mi·49 sec·MS 6
Toward MS 6 East: Downtown Tupelo
22
Keep slight left at fork
170 ft·7 sec
23
Turn left onto MS 6
0.7 mi·1 min·East Main Street
Use the straight lane.
24
Turn right onto North Spring Street
230 ft·10 sec·North Spring Street
25
Arrive at destination
North Spring Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 111.4 miles from Edwards, MS, or about 2h 9m into the drive.
The longest continuous stretch on this route runs about 79.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 58m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 111.4 miles or 2h 9m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 32m
Traffic, exits, and arrival timing usually matter more near Tupelo, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Edwards, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Edwards, MS
This is one driving day of about 222.8 miles and 4h 22m.
Your first comfortable stop window is around 49 miles from Edwards, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS Hwy 25 for about 79.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 111.4 mi from Edwards, MS
· 2h 9m into the drive
The midpoint is around 111.4 miles from Edwards, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before MS Hwy 25 if your tank is already low. That segment runs about 79.6 miles.
Arriving in Tupelo, MS
The final approach into Tupelo, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Tupelo, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Tupelo National Battlefield
National Battlefield
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
2 mi from route
~5 min detour
Free
near mile 222.8
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
5 mi from route
~12 min detour
Free
near mile 222.8
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$33.65 one way
$67.30 round trip
$3.84/gal25.4 MPG avg78 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$36.94
$73.87
premium
$4.56
$39.99
$79.98
diesel
$5.61
$49.19
$98.38
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$34
Meals
$25–$50
Total
$59–$84
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 78 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
66.8
0
$23.39
$10.69
Efficient EV
55.7
0
$19.50
$8.91
EV Truck/SUV
89.1
1
$31.19
$14.26
Gas CO2
78 kg
EV CO2
26 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Edwards, MS
Afternoon
in Edwards on Friday
Local time
1:58 PM
CDT
Current temp
54°F
Unavailable
Live forecast
Destination
Tupelo, MS
Afternoon
in Tupelo on Friday
Local time
1:58 PM
CDT
Current temp
78°F
Unavailable
Live forecast
79°F
Philadelphia, MS
111 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
24 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 22m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Edwards, MS to Tupelo, MS covers 222.8 miles and takes about 4h 22m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MS Hwy 25, MS 25, US Highway 45 Alternate. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 111.4 miles from Edwards, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $33.65 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 16 significant decision points across 222.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: near the start (South Main Street): Navigation decision point; at 0.1 miles (MS 467 / Vicksburg Street): Navigation decision point; at 27.4 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Edwards, MS and Tupelo, MS, road signs point toward Grenada, Memphis and Point.
Mostly flat terrain. The route ranges from 215 ft to 538 ft elevation with about 470 ft of total climbing.
Yes. Nearby national parks include Tupelo National Battlefield, Medgar and Myrlie Evers Home National Monument and Natchez Trace National Scenic Trail.
