Origin
Fredericktown, MO
Morning in Fredericktown on Monday
Local time
10:51 AM
CDT
Current temp
79°F
Unavailable
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Create accountDrive Time
6h 6m
Distance
313.2 mi
504 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$48
one way
EV Charging
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station data
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
East Independence, MO
Momo King
The drive from Fredericktown, MO to East Independence, MO covers 313.2 miles and takes about 6h 6m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Dwight D. Eisenhower Highway for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 80.7 miles on Dwight D Eisenhower Highway. At current regular gas prices, budget about $47.57 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
156.6 miles from Fredericktown, MO
A natural place for your longest stop of the day , about 3h 7m into the drive .
Expect a 6h 6m drive with frequent turns across 313.2 miles of local and secondary roads.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 76 miles in.
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 23 significant decision points across 313.2 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 76 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 76.2 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 88.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Between Fredericktown, MO and East Independence, MO, road signs point toward Chicago and Saint Louis.
Chicago
Saint Louis
| Road | Distance | Duration |
|---|---|---|
| Dwight D Eisenhower Highway | 80.7 mi | 1h 35m |
| U.S. Submarine Veterans' Memorial Highway | 54.4 mi | 58m |
| Dwight D. Eisenhower Highway | 54.3 mi | 58m |
| US 67 | 51.9 mi | 59m |
| Avenue of the Saints | 25.4 mi | 30m |
| I 55 | 20.5 mi | 22m |
| I 270 | 11.5 mi | 14m |
| Sheriff Roger I. Wilson Memorial Highway | 2 mi | 2m |
Step-by-step road directions between Fredericktown, MO and East Independence, MO.
Start on East Main Street
Enter roundabout onto West Main Street
Continue on West Main Street
Enter roundabout onto US 67 Business; MO 72
Continue on US 67 Business; MO 72
Take the ramp
Merge onto US 67
Keep slight right at fork onto US 67
Take the exit
Merge onto I 55
Continue on I 55
Take the exit
Keep slight left at fork
Continue on this road
Merge onto I 270
Take the exit
Keep slight left at fork
Continue on this road
Merge onto I 64; US 40; US 61
Take the exit onto US 40
Merge onto I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Take the exit
Turn right onto South Little Blue Parkway
Turn left onto East R.D. Mize Road
Turn right onto South Jackson Drive
Turn straight onto Holke Road
Turn left onto East Truman Road
Turn right onto Main Road
Turn right onto East 9th Street South
Arrive at destination
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 156.6 miles or 3h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 59m
Traffic, exits, and arrival timing usually matter more near East Independence, MO than in the middle of the route.
Open the route before leaving Fredericktown, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Fredericktown, MO
This is one driving day of about 313.2 miles and 6h 6m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 156.6 mi from Fredericktown, MO · 3h 7m into the drive
Mid-route town
Meal stop
157 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 156.6 miles from Fredericktown, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dwight D Eisenhower Highway if your tank is already low. That segment runs about 80.7 miles.
The final approach into East Independence, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around East Independence, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$47.57 one way
$95.14 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $52.44 | $104.89 |
| premium | $4.80 | $59.13 | $118.25 |
| diesel | $5.64 | $69.58 | $139.16 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$48
Meals
$25–$50
Total
$73–$98
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 109.6 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $33 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 94 | 1 | $32.89 | $15.03 |
| Efficient EV | 78.3 | 0 | $27.40 | $12.53 |
| EV Truck/SUV | 125.3 | 1 | $43.85 | $20.04 |
Gas CO2
110 kg
EV CO2
37 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Fredericktown on Monday
Local time
10:51 AM
CDT
Current temp
79°F
Unavailable
Destination
Morning in East Independence on Monday
Local time
10:51 AM
CDT
Current temp
49°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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Return Trip
East Independence, MO to Fredericktown, MOPlan the drive back the other way.
Explore more options from Fredericktown, MO or browse trips ending in East Independence, MO.
Looking for more statewide routes? Browse MO road trips.
Explore maps for Fredericktown, MO or East Independence, MO on MapSof.net.