Origin
Glendale, MO
Morning in Glendale on Wednesday
Local time
7:23 AM
CDT
Current temp
80°F
Unavailable
Live forecast
Trip from Glendale, MO to East Independence, MO
Data updated 0 seconds ago
Drive Time
8h 9m
Distance
416.6 mi
670 km
Drive Score
9/10
Great drive
Same Day?
2-day trip
Fuel Cost
$65
one way
EV Charging
Loading...
station data
Best Time to Leave
4 AM
8h 1m
★
6 AM
8h 10m
8 AM
8h 26m
10 AM
8h 15m
12 PM
8h 14m
3 PM
8h 16m
5 PM
8h 25m
8 PM
8h 5m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Glendale, MO
Valeria Boltneva
East Independence, MO
Momo King
Trip Overview
The drive from Glendale, MO to East Independence, MO covers 416.6 miles and takes about 8h 9m behind the wheel. It usually feels better as a 2-day road trip than as one long push.
The route leans on I 55, Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway for much of the mileage, and the overall profile is mixed drive. The longest uninterrupted segment is about 162 miles on I 55. At current regular gas prices, budget about $65.13 one way before food or hotel costs.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
208.3 miles from Glendale, MO
A natural place for your longest stop of the day , about 4h 8m into the drive .
Loading map...
Drive Character
The drive from Glendale, MO to East Independence, MO covers 416.6 miles and takes about 8h 9m, using a mix of highways and local roads.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 35 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 55 is the longest continuous segment at about 162 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 179.3 miles in.
Route Complexity
10/10
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 23 significant decision points across 416.6 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 179.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 179.5 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 191.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 23 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
8
179.3 mi into trip
|
~3h 32m in
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chi...
8
179.5 mi into trip
|
~3h 32m in
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left lane.
Toward I 270 West: Kansas City
8
191.8 mi into trip
|
~3h 48m in
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Lo...
8
192 mi into trip
|
~3h 48m in
Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 64 West, US 40 West, US 61 North: Went...
8
217.9 mi into trip
|
~4h 20m in
|
US 40
Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight left lanes.
Exit 1A
Toward I 70 West, US 40 West: Kansas City
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Glendale, MO and East Independence, MO, road signs point toward Chicago and Saint Louis.
Chicago
179.3 mi in
|
~3h 32m
Saint Louis
191.8 mi in
|
~3h 48m
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 55 | 162 mi | 2h 54m |
| Dwight D Eisenhower Highway | 80.7 mi | 1h 35m |
| U.S. Submarine Veterans' Memorial Highway | 54.4 mi | 58m |
| Dwight D. Eisenhower Highway | 54.3 mi | 58m |
| Avenue of the Saints | 25.4 mi | 30m |
| I 270 | 11.5 mi | 14m |
| MO 162 | 9.8 mi | 17m |
| Sheriff Roger I. Wilson Memorial Highway | 2 mi | 2m |
Longest stretch:
I 55
— 162 mi, about 2h 54m
Turn-by-Turn Driving Directions
Step-by-step road directions between Glendale, MO and East Independence, MO.
1
Start on MO VV
0.4 mi
·
1 min
·
MO VV
2
Continue on County Road 282
1.0 mi
·
4 min
·
County Road 282
3
Turn left onto County Road 281
1.7 mi
·
6 min
·
County Road 281
4
Continue on County Road 277
1.1 mi
·
4 min
·
County Road 277
5
Turn right onto MO 162
9.8 mi
·
17 min
·
MO 162
6
At end of road, turn right onto US 61; MO 162
1.0 mi
·
1 min
·
US 61; MO 162
7
Turn left onto US 61; MO 162
0.7 mi
·
1 min
·
US 61; MO 162
8
Take the ramp
0.2 mi
·
24 sec
Toward I 55 North: Sikeston
9
Merge onto I 55
60 mi
·
1 hr 4 min
·
I 55
10
Keep slight left at fork onto I 55
102 mi
·
1 hr 49 min
·
I 55
11
Continue on I 55
1.3 mi
·
1 min
·
Rosa Parks Highway
12
Take the exit
0.2 mi
·
27 sec
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chicago
Use the slight right lane.
13
Keep slight left at fork
388 ft
·
8 sec
Toward I 270 West: Kansas City
Use the slight left lane.
14
Continue on this road
0.7 mi
·
1 min
·
this road
Exit 196
Toward I 270 West
15
Merge onto I 270
11 mi
·
14 min
·
I 270
Use the straight lane.
16
Take the exit
0.1 mi
·
17 sec
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Louis
Use the slight right lane.
17
Keep slight left at fork
0.4 mi
·
48 sec
Toward I 64 West, US 40 West, US 61 North: Wentzville
Use the slight left lane.
18
Continue on this road
0.1 mi
·
9 sec
·
this road
Exit 12
Toward I 64 West, US 40 West, US 61 North: Wentzville
19
Merge onto I 64; US 40; US 61
25 mi
·
30 min
·
Avenue of the Saints
Use the straight lane.
20
Take the exit onto US 40
0.6 mi
·
1 min
·
US 40
Exit 1A
Toward I 70 West, US 40 West: Kansas City
Use the straight / slight left lanes.
21
Merge onto I 70; US 40
81 mi
·
1 hr 35 min
·
Dwight D Eisenhower Highway
22
Continue on I 70; US 40
2.0 mi
·
2 min
·
Sheriff Roger I. Wilson Memorial Highway
23
Continue on I 70; US 40
1.6 mi
·
1 min
·
Highway Patrol Sgt. Benjamin Booth Memorial Highway
24
Continue on I 70; US 40
1.8 mi
·
2 min
·
Dwight D. Eisenhower Highway
25
Continue on I 70; US 40
54 mi
·
58 min
·
U.S. Submarine Veterans' Memorial Highway
26
Continue on I 70; US 40
52 mi
·
56 min
·
Dwight D. Eisenhower Highway
27
Take the exit
0.3 mi
·
40 sec
Exit 17
Toward Little Blue Parkway, 39th Street, Mall Entrance
Use the slight right lane.
28
Turn right onto South Little Blue Parkway
1.6 mi
·
3 min
·
South Little Blue Parkway
29
Turn left onto East R.D. Mize Road
0.2 mi
·
37 sec
·
East R.D. Mize Road
30
Turn right onto South Jackson Drive
1.2 mi
·
2 min
·
South Jackson Drive
31
Turn straight onto Holke Road
0.9 mi
·
2 min
·
Holke Road
32
Turn left onto East Truman Road
0.7 mi
·
1 min
·
East Truman Road
33
Turn right onto Main Road
0.3 mi
·
1 min
·
Main Road
34
Turn right onto East 9th Street South
79 ft
·
3 sec
·
East 9th Street South
35
Arrive at destination
East 9th Street South
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This drive is better paced as a 2-day trip.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 208.3 miles from Glendale, MO, or about 4h 8m into the drive.
The longest continuous stretch on this route runs about 162 miles.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 92 miles or 1h 58m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 208.3 miles or 4h 8m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 208.3 miles or 4h 8m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 6h 59m
Traffic, exits, and arrival timing usually matter more near East Independence, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Glendale, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
+
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from Glendale, MO
Aim for roughly 208 miles and 4.1 hours of wheel time on this day.
Day 2
Finish the approach into East Independence, MO
Aim for roughly 208 miles and 4.1 hours of wheel time on this day.
Your first comfortable stop window is around 92 miles from Glendale, MO.
This route usually feels better as a 2-day drive than as one long push.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on I 55 for about 162 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 208.3 mi from Glendale, MO · 4h 8m into the drive
Mid-route town
Overnight candidate
208 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Find hotels in East Saint Louis, ILOvernight Options
Night 1
208 mi · about 4.1h in
A practical overnight split lands near East Saint Louis, IL after about 208 miles or 4.1 hours of driving.
Find hotelsPacing Suggestions
Fuel and coffee
A short stop after about 92 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 208.3 miles from Glendale, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 55 if your tank is already low. That segment runs about 162 miles.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 208 miles or 4.1 hours on the road.
Arriving in East Independence, MO
The final approach into East Independence, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around East Independence, MO.
On a multi-day trip, keep the last day a little lighter so you reach East Independence, MO with some flexibility left in the schedule.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$65.13 one way
$130.26 round trip
$3.97/gal
25.4 MPG avg
146 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $71.51 | $143.02 |
| premium | $4.89 | $80.17 | $160.34 |
| diesel | $5.61 | $91.98 | $183.96 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$65
Hotel (1n)
$80–$140
Meals
$50–$100
Total
$195–$305
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 145.8 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $44 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 125 | 1 | $43.74 | $20.00 |
| Efficient EV | 104.2 | 1 | $36.45 | $16.66 |
| EV Truck/SUV | 166.6 | 2 | $58.32 | $26.66 |
Gas CO2
146 kg
EV CO2
49 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
East Independence, MO
Morning in East Independence on Wednesday
Local time
7:23 AM
CDT
Current temp
49°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
31 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
8h 9m on the road
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Glendale, MO to East Independence, MO covers 416.6 miles and takes about 8h 9m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 55, Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway. Expect a mix of highway and local road driving.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 208 miles on day one.
The midpoint is about 208.3 miles from Glendale, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $65.13 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 23 significant decision points across 416.6 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 179.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 179.5 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 191.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Glendale, MO and East Independence, MO, road signs point toward Chicago and Saint Louis.
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