Trip from Hereford, TX to San Antonio, TX

Drive Time

7h 34m

Distance

496.7 mi

Route Type

Turn-heavy local drive

Long day trip

Trip Overview

The drive from Hereford, TX to San Antonio, TX covers 496.7 miles and takes about 7h 34m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on West 1st Street, South 25 Mile Avenue, North Main Street for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $73.90 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

248.4 miles from Hereford, TX

A natural place for your longest stop of the day.

Drive Character

Expect a 7h 34m drive with frequent turns across 496.7 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 40 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
West 1st Street is one of the defining roads on this drive.

Main Roads

Road Distance Duration
West 1st Street 0 mi 0m
South 25 Mile Avenue 0 mi 0m
North Main Street 0 mi 0m
East Delano Avenue 0 mi 0m
Avenue Q 0 mi 0m
Slaton Road 0 mi 0m
Highway 84 0 mi 0m
Trooper Jerry Don Davis Memorial Highway 0 mi 0m
Longest stretch: West 1st Street — 0 mi, about 0m

Step-by-Step Directions

1

Start on the route

2

Turn right onto West 1st Street

3

Turn left onto South 25 Mile Avenue

4

Turn right

5

Turn straight onto North Main Street

6

Continue straight

7

Turn straight

8

At the end of the road, turn left onto East Delano Avenue

9

Turn left

10

Merge slight left onto Avenue Q

11

Continue on Slaton Road

12

Continue on East Highway 84

13

Continue on Trooper Jerry Don Davis Memorial Highway

14

Continue on East Highway 84

15

Continue on North US Highway 84

16

Turn left onto East 15th Street

17

Turn right onto Ralls Road

18

Turn straight onto North Avenue F

19

At the end of the road, turn left onto US Highway 84

20

Keep slight left to continue on I 20 East, US 84 East: Abilene

21

Take the exit slight right toward SH 70 South, SH 70 Business: Sweetwater, San Angelo

22

Turn slight left onto Southwest Georgia Avenue

23

Turn right onto Lamar Street

24

Continue on State Highway 70

25

Turn left onto State Highway 153

26

Turn right

27

Turn left

28

At the end of the road, turn right onto Hutchings Avenue

29

Turn left onto South 7th Street

30

Continue on Grassmeyer Street

31

Continue on Ellis Street

32

Take the exit left toward I 10 East: San Antonio

33

Continue straight

34

Keep slight right

35

Keep slight right to continue on McDermott Freeway

36

Take the exit slight right toward Santa Rosa Street, Downtown

37

Turn straight onto North Pecos-La Trinidad

38

Keep slight right to continue on North Pecos-La Trinidad

39

Turn left onto Dolorosa Street

40

Arrive at your destination

When to Leave

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 248.4 miles from Hereford, TX.

This is a comfortable same-day trip.

Drive Plan

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 109 miles

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 248.4 miles

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Last hour of driving

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Hereford, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

Trip Strategy

Day 1

Settle into the route from Hereford, TX

This is one driving day of about 496.7 miles and 7h 34m.

Your first comfortable stop window is around 109 miles from Hereford, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.

Best Stop Towns on This Route

These towns line up with the pace of this drive and give you clearer places to stop with a purpose.

Late stop town

Meal stop

Sweetwater, TX

248 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Travel Advice

Arrival Notes

The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Stops Along the Way

Halfway Point

Midpoint

About 248.4 mi from Hereford, TX

Lubbock, TX

Fuel and coffee

A short stop after about 109 miles helps settle the day before fatigue starts building.

Sweetwater, TX

Meal break

The midpoint is around 248.4 miles from Hereford, TX, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Fuel Type $/gal One Way Round Trip
regular $3.78 $73.90 $147.80
midgrade $4.25 $83.15 $166.30
premium $4.59 $89.78 $179.56
diesel $3.99 $78.08 $156.17

Based on 25.4 MPG average. Estimated CO2 emission: 173.8 kg one way.

Frequently Asked Questions

The drive from Hereford, TX to San Antonio, TX covers 496.7 miles and takes about 7h 34m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are West 1st Street, South 25 Mile Avenue, North Main Street. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 248.4 miles from Hereford, TX. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $73.90 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

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