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Trip from Hillsborough, NC to Winston-Salem, NC

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

1h 23m

Distance

68.2 mi

110 km

Drive Score

7/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$11

one way

EV Charging

Unknown

Best Time to Leave

Save up to 19 min
4 AM
1h 17m ★
6 AM
1h 23m
8 AM
1h 36m
10 AM
1h 28m
12 PM
1h 27m
3 PM
1h 29m
5 PM
1h 36m
8 PM
1h 20m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

town in and county seat of Orange County, North Carolina, United States

Hillsborough, NC

Wikimedia Commons

Trip Overview

The drive from Hillsborough, NC to Winston-Salem, NC covers 68.2 miles and takes about 1h 23m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on I 85, I 40, Salem Parkway for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 32.5 miles on I 85. At current regular gas prices, budget about $10.66 one way before food or hotel costs.

About the Cities

Arriving in Winston-Salem, NC

Full guide →

Winston-Salem is a city in North Carolina. It has an approximate population of 251,000 (2022). Winston-Salem is one of three cities that make up the Piedmont Triad; the others are Greensboro and High Point.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 23m. Total distance: 68.2 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 23m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (97%). Some complex stretches to watch for.

Drive Character

This is a 1h 23m highway drive covering 68.2 miles, with most of the trip on I 85 and I 40. The longest continuous stretch is about 32.5 miles on I 85.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 10 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 85 is the longest continuous segment at about 32.5 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on I 85 and I 40. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 1.3 miles in.

Driving Effort 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 68.2 miles you will encounter 8 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 1.3 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 34 miles (I 40): Highway fork - watch signs carefully. Lane positioning matters here; at 41.6 miles (I 40; US 220): Highway fork - watch signs carefully. Lane positioning matters here.

Critical Maneuvers

5 of 8 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

7
1.3 mi into trip | ~3m in

Take the ramp toward I 85 South, NC 86 North: Greensboro

Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / right lanes. Toward I 85 South, NC 86 North: Greensboro
6
34 mi into trip | ~41m in | I 40

Keep slight right at fork onto I 40

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight left lanes.
6
41.6 mi into trip | ~50m in | I 40; US 220

Keep slight right at fork onto I 40; US 220

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane.
8
54.2 mi into trip | ~1h 6m in | US 421 / Salem Parkway

Keep slight right at fork onto US 421 / Salem Parkway toward US 421 North: Kernersville

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane. Exit 206 Toward US 421 North: Kernersville
7
67.6 mi into trip | ~1h 22m in

Take the exit toward Main Street

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 233A Toward Main Street

Main Roads

Road Distance Duration
I 85 32.5 mi 37m
I 40 20.3 mi 24m
Salem Parkway 13.4 mi 16m
South Churton Street 1.3 mi 3m
South Main Street 0.4 mi <1m
West King Street <0.1 mi <1m
North Main Street

Some road-level metrics are being recalculated.

Longest stretch: I 85 — 32.5 mi, about 37m

Turn-by-Turn Driving Directions

Step-by-step road directions between Hillsborough, NC and Winston-Salem, NC.

1

Start on West King Street

96 ft · 8 sec · West King Street
2

Turn right onto US 70 Business; NC 86

1.3 mi · 3 min · South Churton Street
Use the straight / right lanes.
3

Take the ramp

0.2 mi · 28 sec
Toward I 85 South, NC 86 North: Greensboro Use the straight / right lanes.
4

Merge onto I 85; NC 86 Truck

32 mi · 37 min · I 85; NC 86 Truck
Use the straight / slight right lanes.
5

Keep slight right at fork onto I 40

7.7 mi · 9 min · I 40
Use the straight / slight left lanes.
6

Keep slight right at fork onto I 40; US 220

13 mi · 15 min · I 40; US 220
Use the straight lane.
7

Keep slight right at fork onto US 421

13 mi · 16 min · Salem Parkway
Exit 206 Toward US 421 North: Kernersville Use the straight lane.
8

Take the exit

0.2 mi · 28 sec
Exit 233A Toward Main Street Use the slight right lane.
9

Turn slight right onto South Main Street

0.4 mi · 44 sec · South Main Street
Use the straight lane.
10

Arrive at destination

North Main Street

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 34.1 mi from Hillsborough, NC · 41m into the drive

Mid-route town

Meal stop

Greensboro, NC

34 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

City of Graham, NC

Fuel and coffee

A short stop after about 15 miles helps settle the day before fatigue starts building.

Greensboro, NC

Meal break

The midpoint is around 34.1 miles from Hillsborough, NC, which is a good place for a longer meal and fuel stop.

Arriving in Winston-Salem, NC

The final approach into Winston-Salem, NC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$10.66 one way

$21.33 round trip

$3.97/gal 25.4 MPG avg 24 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $11.66 $23.32
premium $4.70 $12.62 $25.24
diesel $5.61 $15.06 $30.12

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$11

Estimated CO2 emission: 23.9 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $7 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 20.5 0 $7.16 $3.27
Efficient EV 17.1 0 $5.97 $2.73
EV Truck/SUV 27.3 0 $9.55 $4.36

Gas CO2

24 kg

EV CO2

8 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 17, 2026

Origin

Hillsborough, NC

Morning in Hillsborough on Saturday

Local time

10:23 AM

EDT

Current temp

56°F

Unavailable

Live forecast

Destination

Winston-Salem, NC

Morning in Winston-Salem on Saturday

Local time

10:23 AM

EDT

Current temp

42°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

14 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

1h 23m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Hillsborough, NC to Winston-Salem, NC covers 68.2 miles and takes about 1h 23m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are I 85, I 40, Salem Parkway. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 34.1 miles from Hillsborough, NC. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $10.66 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.

This drive requires moderate attention. Across 68.2 miles you will encounter 8 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

The main spots that need attention: at 1.3 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 34 miles (I 40): Highway fork - watch signs carefully. Lane positioning matters here; at 41.6 miles (I 40; US 220): Highway fork - watch signs carefully. Lane positioning matters here.

The route from Hillsborough, NC to Winston-Salem, NC does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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