Origin
Iuka, MS
Evening in Iuka on Wednesday
Local time
5:30 PM
CDT
Current temp
77°F
Unavailable
Live forecast
Trip from Iuka, MS to Biloxi, MS
Last recalculated Apr 15, 2026
Drive Time
5h 56m
Distance
371.7 mi
598 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$56
one way
Best Time to Leave
4 AM
5h 43m
★
6 AM
5h 56m
8 AM
6h 22m
10 AM
6h 5m
12 PM
6h 3m
3 PM
6h 7m
5 PM
6h 21m
8 PM
5h 49m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Iuka, MS
大 董
Biloxi, MS
Wikimedia Commons
Trip Overview
The drive from Iuka, MS to Biloxi, MS covers 371.7 miles and takes about 5h 56m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on South Fulton Street, East Quitman Street, Battleground Drive for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $56.14 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
185.8 miles from Iuka, MS
A natural place for your longest stop of the day , about 2h 58m into the drive .
Drive Character
Expect a 5h 56m drive with frequent turns across 371.7 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 37 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
South Fulton Street is one of the defining roads on this drive.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Route Complexity
3/10
Easy - simple navigation with a manageable amount of wheel time
This is a straightforward 5h 56m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Iuka, MS to Biloxi, MS is straightforward, with well-signed roads and simple exits.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| South Fulton Street | — | — |
| East Quitman Street | — | — |
| Battleground Drive | — | — |
| Veterans Memorial Drive | — | — |
| US 72 West | — | — |
| MS 365 | — | — |
| US 45 South | — | — |
| Highway 45 | — | — |
Some road-level metrics are being recalculated.
Longest stretch:
South Fulton Street
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between Iuka, MS and Biloxi, MS.
1
Start on East Eastport Street
174 ft
·
10 sec
·
East Eastport Street
2
Turn right onto South Fulton Street
0.2 mi
·
48 sec
·
South Fulton Street
3
Turn right onto East Quitman Street
0.5 mi
·
58 sec
·
East Quitman Street
4
Turn left onto Battleground Drive
1.0 mi
·
1 min
·
Battleground Drive
5
Turn left onto Veterans Memorial Drive
0.2 mi
·
21 sec
·
Veterans Memorial Drive
6
Take the ramp slight right toward US 72 West: Corinth
0.3 mi
·
47 sec
·
US 72 West: Corinth
7
Merge slight left
7.1 mi
·
8 min
8
Take the exit slight right toward MS 365: Cairo, Miss., Savannah, Tenn.
0.1 mi
·
27 sec
·
MS 365: Cairo, Miss., Savannah, Tenn
9
Turn right
8.5 mi
·
11 min
10
Turn right
12 mi
·
15 min
11
At the end of the road, turn right
6.6 mi
·
9 min
12
Keep slight left to continue on US 45 South, MS 30 West: Tupelo, New Albany
6.4 mi
·
8 min
·
US 45 South, MS 30 West: Tupelo, New Albany
13
Continue straight
33 mi
·
39 min
14
Continue straight
1.4 mi
·
1 min
15
Continue straight
2.2 mi
·
2 min
16
Continue straight
1.5 mi
·
1 min
17
Continue straight
0.7 mi
·
49 sec
18
Continue straight
1.4 mi
·
1 min
19
Continue on US Highway 45 Alternate
55 mi
·
1 hr 6 min
·
US Highway 45 Alternate
20
Continue on US Highway 45 Aiternate
61 mi
·
1 hr 9 min
·
US Highway 45 Aiternate
21
Keep slight right
3.9 mi
·
4 min
22
Take the exit slight right toward I 59 South, I 20 West: Meridian
0.5 mi
·
1 min
·
I 59 South, I 20 West: Meridian
23
Merge slight left
6.3 mi
·
7 min
24
Continue straight
1.8 mi
·
2 min
25
Keep slight left to continue on I 59 South: Laurel, New Orleans
89 mi
·
1 hr 36 min
·
I 59 South: Laurel, New Orleans
26
Take the exit slight right toward US 98 East: Lucedale, Mobile
3.2 mi
·
4 min
·
US 98 East: Lucedale, Mobile
27
Take the exit slight right toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
0.3 mi
·
44 sec
·
US 49: Wiggins, Gulfport, Mississippi Gulf Coast
28
Keep slight left to continue on Multi Purpose Center, Hattiesburg
0.2 mi
·
28 sec
·
Multi Purpose Center, Hattiesburg
29
Turn right
42 mi
·
49 min
30
Take the exit slight right toward MS 67 South: D'Iberville, Biloxi
0.8 mi
·
1 min
·
MS 67 South: D'Iberville, Biloxi
31
Continue on Biloxi-D'Iberville Scenic Expressway
20 mi
·
24 min
·
Biloxi-D'Iberville Scenic Expressway
32
Continue straight
3.2 mi
·
4 min
33
Take the exit slight right toward Division Street
0.4 mi
·
47 sec
·
Division Street
34
Turn left onto Division Street
0.6 mi
·
1 min
·
Division Street
35
Turn right onto Main Street
0.5 mi
·
1 min
·
Main Street
36
Turn left onto Howard Avenue
92 ft
·
3 sec
·
Howard Avenue
37
Arrive at your destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 185.8 miles from Iuka, MS, or about 2h 58m into the drive.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 82 miles or 1h 18m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 185.8 miles or 2h 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 58m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Iuka, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Iuka, MS
This is one driving day of about 371.7 miles and 5h 56m.
Your first comfortable stop window is around 82 miles from Iuka, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 185.8 mi from Iuka, MS · 2h 58m into the drive
Mid-route town
Meal stop
186 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 82 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 185.8 miles from Iuka, MS, which is a good place for a longer meal and fuel stop.
Arriving in Biloxi, MS
The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$56.14 one way
$112.27 round trip
$3.84/gal
25.4 MPG avg
130 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $61.62 | $123.25 |
| premium | $4.56 | $66.72 | $133.43 |
| diesel | $5.61 | $82.07 | $164.13 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$56
Meals
$25–$50
Total
$81–$106
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 130.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $39 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 111.5 | 1 | $39.03 | $17.84 |
| Efficient EV | 92.9 | 1 | $32.52 | $14.87 |
| EV Truck/SUV | 148.7 | 1 | $52.04 | $23.79 |
Gas CO2
130 kg
EV CO2
43 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Biloxi, MS
Evening in Biloxi on Wednesday
Local time
5:30 PM
CDT
Current temp
61°F
Unavailable
Live forecast
79°F
Meridian, MS
186 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
16 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 56m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Iuka, MS to Biloxi, MS covers 371.7 miles and takes about 5h 56m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are South Fulton Street, East Quitman Street, Battleground Drive. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 185.8 miles from Iuka, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $56.14 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a straightforward 5h 56m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
This route does not have any notably tricky sections. Most of the drive from Iuka, MS to Biloxi, MS is straightforward, with well-signed roads and simple exits.
The route from Iuka, MS to Biloxi, MS does not surface many named destination signs beyond the main corridor.
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