Origin
Jackson, MS
Late night in Jackson on Sunday
Local time
2:24 AM
CDT
Current temp
58°F
Mostly Clear
Drive Time
3h 23m
Distance
165.2 mi
266 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$25
one way
Photo: 大 董
The drive from Jackson, MS to Biloxi, MS covers 165.2 miles and takes about 3h 23m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Highway 49 South, US 49, Biloxi-D'Iberville Scenic Expressway for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 80.3 miles on Highway 49 South. At current regular gas prices, budget about $25.25 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
82.6 miles from Jackson, MS
A natural place for your longest stop of the day , about 1h 42m into the drive .
This is a 3h 23m highway drive covering 165.2 miles, with most of the trip on Highway 49 South and US 49. The longest continuous stretch is about 80.3 miles on Highway 49 South.
Mostly flat terrain
Total Climb
398 ft
Total Descent
657 ft
Highest Point
478 ft
~41.3 mi in
Elevation Range
458 ft
This is a straightforward highway drive that stays mostly on Highway 49 South and US 49. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 3.2 miles in near US 49.
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 17 significant decision points across 165.2 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 3.2 miles (US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 85.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 93.8 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight right at fork onto US 49 toward Richland, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit toward I 59 South: New Orleans, Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Between Jackson, MS and Biloxi, MS, road signs point toward Gulf Coast, Mississippi Gulf Coast, Mobile, Gulfport, Multi Purpose Center and Hattiesburg.
Gulf Coast
Mississippi Gulf Coast
Mobile
Gulfport
Multi Purpose Center
Hattiesburg
| Road | Distance | Duration |
|---|---|---|
| Highway 49 South | 80.3 mi | 1h 37m |
| US 49 | 44.1 mi | 53m |
| Biloxi-D'Iberville Scenic Expressway | 20.5 mi | 24m |
| Lance Corporal Roy M Wheat Memorial Highway | 7.7 mi | 8m |
| US 98 | 3.2 mi | 4m |
| I 110 | 3.2 mi | 4m |
| I 55 | 0.8 mi | 1m |
| Division Street | 0.6 mi | 1m |
Step-by-step road directions between Jackson, MS and Biloxi, MS.
Start on East Pearl Street
Turn left onto South Lamar Street
Turn left onto East Pascagoula Street
Take the ramp
Keep slight right at fork
Merge onto I 55
Take the exit
Keep slight right at fork onto US 49
Merge onto US 49
Continue on US 49; MS 42
Continue on US 49; MS 42
Take the exit
Merge onto I 59
Take the exit onto US 98
Take the exit
Keep slight left at fork
Turn right onto US 49
Take the exit
Continue on MS 67
Continue on I 110
Take the exit
Turn left onto Division Street
Turn right onto Main Street
Turn left onto Howard Avenue
Arrive at destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 39m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 82.6 miles or 1h 42m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 45m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Open the route before leaving Jackson, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Jackson, MS
This is one driving day of about 165.2 miles and 3h 23m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 82.6 mi from Jackson, MS · 1h 42m into the drive
Mid-route town
Meal stop
83 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 82.6 miles from Jackson, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Highway 49 South if your tank is already low. That segment runs about 80.3 miles.
The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$25.25 one way
$50.51 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $27.70 | $55.40 |
| premium | $4.61 | $29.98 | $59.97 |
| diesel | $5.64 | $36.70 | $73.40 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$25
Meals
$25–$50
Total
$50–$75
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 57.8 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $17 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 49.6 | 0 | $17.35 | $7.93 |
| Efficient EV | 41.3 | 0 | $14.45 | $6.61 |
| EV Truck/SUV | 66.1 | 0 | $23.13 | $10.57 |
Gas CO2
58 kg
EV CO2
19 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Jackson on Sunday
Local time
2:24 AM
CDT
Current temp
58°F
Mostly Clear
Destination
Late night in Biloxi on Sunday
Local time
2:24 AM
CDT
Current temp
65°F
Mostly Clear
Along the Route
85°F
Magee, MS
83 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
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