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Trip from Jefferson City, MO to Saint Ann, MO

Drive Time

2h 20m

Distance

118.7 mi

191 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$18

one way

EV Charging

None

0 DC fast

Best Time to Leave

Save up to 30 min
4 AM
2h 10m ★
6 AM
2h 20m
8 AM
2h 40m
10 AM
2h 27m
12 PM
2h 25m
3 PM
2h 28m
5 PM
2h 39m
8 PM
2h 14m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly
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Downtown Jefferson City, MO, MO

Jefferson City, MO

life vibes

Downtown Saint Ann, MO, MO

Saint Ann, MO

Sami Aksu

Trip Overview

The drive from Jefferson City, MO to Saint Ann, MO covers 118.7 miles and takes about 2h 20m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Dwight D. Eisenhower Highway, US 54, Saint Charles Rock Road for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 85.8 miles on Dwight D. Eisenhower Highway. At current regular gas prices, budget about $18.03 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

0 planned breaks

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

59.4 miles from Jefferson City, MO

A natural place for your longest stop of the day , about 1h 8m into the drive .

Drive Character

Expect a 2h 20m drive with frequent turns across 118.7 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 13 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D. Eisenhower Highway is the longest continuous segment at about 85.8 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near Jefferson Street.

Route Complexity 4/10

Easy - simple navigation with a manageable amount of wheel time

This is a straightforward 2h 20m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: near the start (Jefferson Street): Navigation decision point; at 0.7 miles: Multiple destination signs - pick the right one; at 30.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 9 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0 mi into trip | ~0m in | Jefferson Street

Turn right onto Jefferson Street

Navigation decision point

5
0.7 mi into trip | ~2m in

Take the ramp toward US 54 East, US 63 North: Fulton, Columbia

Multiple destination signs - pick the right one

Toward US 54 East, US 63 North: Fulton, Columbi...
5
30.4 mi into trip | ~34m in

Take the exit toward I 70 East, US 40 East: Saint Louis

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Toward I 70 East, US 40 East: Saint Louis
5
30.7 mi into trip | ~35m in | I 70; US 40 / Dwight D. Eisenhower Highway

Merge onto I 70; US 40 / Dwight D. Eisenhower Highway

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
7
116.5 mi into trip | ~2h 15m in

Take the exit toward MO 180: Saint Charles Rock Road

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 234 Toward MO 180: Saint Charles Rock Road

Main Roads

Road Distance Duration
Dwight D. Eisenhower Highway 85.8 mi 1h 40m
US 54 29.6 mi 32m
Saint Charles Rock Road 1.9 mi 3m
West McCarty Street 0.6 mi 1m
San Jose Lane <0.1 mi <1m
Jefferson Street <0.1 mi <1m
East Wall Way <0.1 mi <1m
Longest stretch: Dwight D. Eisenhower Highway — 85.8 mi, about 1h 40m

Turn-by-Turn Driving Directions

Step-by-step road directions between Jefferson City, MO and Saint Ann, MO.

1

Start on East Wall Way

154 ft · 13 sec · East Wall Way
2

Turn right onto Jefferson Street

253 ft · 15 sec · Jefferson Street
3

Turn right onto West McCarty Street

0.6 mi · 1 min · West McCarty Street
4

Take the ramp right toward US 54 East, US 63 North: Fulton, Columbia

0.1 mi · 18 sec · US 54 East, US 63 North: Fulton, Columbia
5

Merge slight left

30 mi · 32 min
6

Take the exit slight right toward I 70 East, US 40 East: Saint Louis

0.2 mi · 15 sec · I 70 East, US 40 East: Saint Louis
7

Merge slight left onto Dwight D. Eisenhower Highway

86 mi · 1 hr 40 min · Dwight D. Eisenhower Highway
8

Take the exit slight right toward MO 180: Saint Charles Rock Road

0.3 mi · 32 sec · MO 180: Saint Charles Rock Road
9

Turn right onto Saint Charles Rock Road

0.7 mi · 1 min · Saint Charles Rock Road
10

Continue on Saint Charles Rock Road

1.2 mi · 2 min · Saint Charles Rock Road
11

Turn right onto San Jose Lane

295 ft · 13 sec · San Jose Lane
12

Continue on San Jose Lane

125 ft · 5 sec · San Jose Lane
13

Arrive at your destination

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 59.4 miles from Jefferson City, MO, or about 1h 8m into the drive.
The longest continuous stretch on this route runs about 85.8 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 32m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 59.4 miles or 1h 8m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 53m

Traffic, exits, and arrival timing usually matter more near Saint Ann, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Jefferson City, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Jefferson City, MO

This is one driving day of about 118.7 miles and 2h 20m.

Your first comfortable stop window is around 80 miles from Jefferson City, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
You may only need one short stretch stop if conditions stay smooth.
The longest stretch is on Dwight D. Eisenhower Highway for about 85.8 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 59.4 mi from Jefferson City, MO · 1h 8m into the drive

Downtown Alton, IL, IL

Mid-route town

Meal stop

Alton, IL

59 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Alton, IL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Quincy, IL

Meal break

The midpoint is around 59.4 miles from Jefferson City, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 85.8 miles.

Arriving in Saint Ann, MO

The final approach into Saint Ann, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Saint Ann, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Gateway Arch National Park

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

13 mi from route ~31 min detour $19 near mile 118.7
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$18.03 one way

$36.06 round trip

$3.86/gal 25.4 MPG avg 42 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $19.88 $39.75
premium $4.80 $22.41 $44.82
diesel $5.64 $26.37 $52.74

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$18

Meals

$25–$50

Total

$43–$68

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 41.5 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $12 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 35.6 0 $12.46 $5.70
Efficient EV 29.7 0 $10.39 $4.75
EV Truck/SUV 47.5 0 $16.62 $7.60

Gas CO2

42 kg

EV CO2

14 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Jefferson City, MO

Late night in Jefferson City on Monday

Local time

5:03 AM

CDT

Current temp

51°F

Unavailable

Live forecast

Destination

Saint Ann, MO

Late night in Saint Ann on Monday

Local time

5:03 AM

CDT

Current temp

46°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

5 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 20m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Jefferson City, MO to Saint Ann, MO covers 118.7 miles and takes about 2h 20m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D. Eisenhower Highway, US 54, Saint Charles Rock Road. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 59.4 miles from Jefferson City, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $18.03 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a straightforward 2h 20m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: near the start (Jefferson Street): Navigation decision point; at 0.7 miles: Multiple destination signs - pick the right one; at 30.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
The route from Jefferson City, MO to Saint Ann, MO does not surface many named destination signs beyond the main corridor.

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