Origin
Saint Ann, MO
Afternoon in Saint Ann on Sunday
Local time
2:27 PM
CDT
Current temp
46°F
Unavailable
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Create accountDrive Time
5h 33m
Distance
292.2 mi
470 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$44
one way
Saint Ann, MO
Sami Aksu
Saint Joseph, MO
Andrés Oliver Joya Zapata
Spanning 292.2 miles across Missouri, this trek from Saint Ann to Saint Joseph is a straightforward journey through the heart of the Midwest. You can expect to spend about 5 hours and 33 minutes behind the wheel, making it a manageable, albeit long, day trip for most drivers. With a fuel budget of approximately $44, it is an economical way to traverse the state. The path primarily utilizes a combination of I-70, I-29, and I-435 to connect your starting point to your final destination. Since you are staying within the same region, the transition between these two Missouri hubs is seamless and practical.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
146.1 miles from Saint Ann, MO
A natural place for your longest stop of the day , about 2h 47m into the drive .
This trip is a quintessential highway-focused drive, with 93% of your time spent on major interstates. You will settle into a steady rhythm early on, as the route features a significant 217.3-mile stretch on I-70. While the high percentage of interstate driving ensures efficiency, you should be prepared for the consistent pace that comes with such long, uninterrupted segments. As you transition between the primary highways, the drive maintains a predictable character that prioritizes speed and directness over technical maneuvers. Expect a functional, high-speed experience that gets you from point A to point B with minimal deviation.
This is a straightforward highway drive that stays mostly on I 70 and I 29. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near MO 180 / Saint Charles Rock Road.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 10 significant decision points across 292.2 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (MO 180 / Saint Charles Rock Road): Lane positioning matters here; at 2.1 miles: Lane positioning matters here; at 2.4 miles (I 70): Merge point - match speed before joining. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn left onto MO 180 / Saint Charles Rock Road
Lane positioning matters here
Take the ramp toward I 70 West
Lane positioning matters here
Merge onto I 70
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward I 435 North, US 24 East: Des Moines
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork onto I 29; US 71 toward I 29 North, US 71 North: Saint Joseph
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
| Road | Distance | Duration |
|---|---|---|
| I 70 | 217.3 mi | 4h 6m |
| I 29 | 26 mi | 27m |
| I 435 | 20.9 mi | 22m |
| Lamar Hunt Memorial Highway | 7.8 mi | 9m |
| I 229 | 5.7 mi | 6m |
| Truman/Eisenhower Presidential Highway | 5.6 mi | 6m |
| Saint Charles Rock Road | 2 mi | 3m |
| Clifton J. Scott Memorial Highway | 1.8 mi | 2m |
Step-by-step road directions between Saint Ann, MO and Saint Joseph, MO.
Start on San Jose Lane
Turn left onto MO 180
Take the ramp
Merge onto I 70
Continue on I 70
Continue on I 70
Continue on I 70
Continue on I 70
Take the exit
Merge onto I 435; US 24
Continue on I435 N
Continue on I 435
Keep slight left at fork onto I 29; US 71
Take the exit
Continue on I 229
Take the exit
Continue on Edmond Street
Turn left onto I 29 Business
Turn right onto I 29 Business
Turn slight right onto Walter Welsh Avenue
Arrive at destination
To keep your energy levels steady, plan for at least one meaningful stop during your 5-hour and 33-minute journey. Given the heavy reliance on I-70 and I-29, traffic patterns near major junctions can fluctuate, so checking for delays before you pull out of Saint Ann is a smart move. Because the longest stretch is over 200 miles, ensure your fuel tank is topped off before you commit to the primary interstate corridor to avoid unnecessary stress. While this trip is easily completed in a single day, the flexibility of the route allows you to adjust your departure time to avoid peak commute hours. Prioritize steady pacing to make the most of the highway-heavy infrastructure.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 32m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 146.1 miles or 2h 47m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 35m
Traffic, exits, and arrival timing usually matter more near Saint Joseph, MO than in the middle of the route.
Open the route before leaving Saint Ann, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Ann, MO
This is one driving day of about 292.2 miles and 5h 33m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 146.1 mi from Saint Ann, MO · 2h 47m into the drive
Mid-route town
Meal stop
146 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 146.1 miles from Saint Ann, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 70 if your tank is already low. That segment runs about 217.3 miles.
The final approach into Saint Joseph, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Saint Joseph, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$44.38 one way
$88.76 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $48.93 | $97.85 |
| premium | $4.80 | $55.16 | $110.32 |
| diesel | $5.64 | $64.92 | $129.83 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$44
Meals
$25–$50
Total
$69–$94
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 102.2 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $31 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 87.7 | 1 | $30.68 | $14.03 |
| Efficient EV | 73.1 | 0 | $25.57 | $11.69 |
| EV Truck/SUV | 116.9 | 1 | $40.91 | $18.70 |
Gas CO2
102 kg
EV CO2
34 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Saint Ann on Sunday
Local time
2:27 PM
CDT
Current temp
46°F
Unavailable
Destination
Afternoon in Saint Joseph on Sunday
Local time
2:27 PM
CDT
Current temp
45°F
Unavailable
Along the Route
55°F
Quincy, IL
146 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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