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Trip from Joplin, MO to Sainte Genevieve, MO

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

6h 3m

Distance

309.9 mi

499 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$48

one way

EV Charging

Unknown

Best Time to Leave

Save up to 39 min
4 AM
5h 50m ★
6 AM
6h 3m
8 AM
6h 29m
10 AM
6h 12m
12 PM
6h 10m
3 PM
6h 14m
5 PM
6h 28m
8 PM
5h 56m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in southern Jasper County and northern Newton County, Missouri, USA

Joplin, MO

Wikimedia Commons

Downtown Sainte Genevieve, MO, MO

Sainte Genevieve, MO

Jermaine Lewis

Trip Overview

The drive from Joplin, MO to Sainte Genevieve, MO covers 309.9 miles and takes about 6h 3m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on East 7th Street, Cimarron Road, I 44 East for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $48.45 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

154.9 miles from Joplin, MO

A natural place for your longest stop of the day , about 3h 1m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 6h 3m. Total distance: 309.9 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

6h 3m drive, plan rest stops for pacing.

First-Time Driver

Mostly highway driving (0%). Straightforward navigation.

Scenic Drive

Turn-heavy local drive route profile.

Drive Character

Expect a 6h 3m drive with frequent turns across 309.9 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 24 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
East 7th Street is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Driving Effort 3/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

The route itself is not hard, but at 6h 3m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Joplin, MO to Sainte Genevieve, MO is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
East 7th Street
Cimarron Road
I 44 East
Congressman Gene Taylor Highway
MO 30
West Gravois Avenue
East Gravois Avenue
Metropolitan Boulevard

Some road-level metrics are being recalculated.

Longest stretch: East 7th Street — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Joplin, MO and Sainte Genevieve, MO.

1

Start on the route

220 ft · 18 sec · the route
2

At the end of the road, turn right

194 ft · 19 sec
3

Turn left onto East 7th Street

6.8 mi · 14 min · East 7th Street
4

Continue on Cimarron Road

0.9 mi · 1 min · Cimarron Road
5

Take the ramp slight right toward I 44 East, I 49 North, US 71 North: Springfield, Kansas City

0.6 mi · 1 min · I 44 East, I 49 North, US 71 North: Springfield, Kansas City
6

Merge slight left onto Congressman Gene Taylor Highway

223 mi · 4 hr 1 min · Congressman Gene Taylor Highway
7

Take the exit slight right toward MO WW, MO AB, MO 30: Saint Clair

0.2 mi · 23 sec · MO WW, MO AB, MO 30: Saint Clair
8

Turn right

0.1 mi · 22 sec
9

Continue on West Gravois Avenue

0.2 mi · 25 sec · West Gravois Avenue
10

Take the exit slight right toward MO 30, MO 47

190 ft · 5 sec · MO 30, MO 47
11

Merge slight left onto East Gravois Avenue

27 mi · 38 min · East Gravois Avenue
12

Turn right

12 mi · 17 min
13

Take the exit slight right

180 ft · 5 sec
14

Turn right onto Metropolitan Boulevard

0.1 mi · 15 sec · Metropolitan Boulevard
15

Enter the roundabout and take exit 3 toward I 55 South: Cape Girardeau

217 ft · 10 sec · I 55 South: Cape Girardeau
16

Exit the roundabout onto I 55 South: Cape Girardeau

0.2 mi · 10 sec · I 55 South: Cape Girardeau
17

Merge slight left onto Jeff McBride Memorial Highway

30 mi · 31 min · Jeff McBride Memorial Highway
18

Take the exit slight right toward MO O

0.2 mi · 31 sec · MO O
19

Turn left

0.3 mi · 38 sec
20

Turn right

7.3 mi · 10 min
21

Turn left onto Market Street

1.2 mi · 2 min · Market Street
22

Turn left onto South Main Street

0.2 mi · 25 sec · South Main Street
23

Turn right onto Jefferson Street

436 ft · 19 sec · Jefferson Street
24

Arrive at your destination

Trip Plan

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 154.9 miles from Joplin, MO, or about 3h 1m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 68 miles or 1h 19m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 154.9 miles or 3h 1m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 57m

Traffic, exits, and arrival timing usually matter more near Sainte Genevieve, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Joplin, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Joplin, MO

This is one driving day of about 309.9 miles and 6h 3m.

Your first comfortable stop window is around 68 miles from Joplin, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 154.9 mi from Joplin, MO · 3h 1m into the drive

Downtown Byrnes Mill, MO, MO

Mid-route town

Meal stop

Byrnes Mill, MO

155 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Morgan, MO

Fuel and coffee

A short stop after about 68 miles helps settle the day before fatigue starts building.

Byrnes Mill, MO

Meal break

The midpoint is around 154.9 miles from Joplin, MO, which is a good place for a longer meal and fuel stop.

Arriving in Sainte Genevieve, MO

The final approach into Sainte Genevieve, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Sainte Genevieve, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$48.45 one way

$96.90 round trip

$3.97/gal 25.4 MPG avg 108 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $53.20 $106.39
premium $4.89 $59.64 $119.27
diesel $5.61 $68.42 $136.84

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$48

Meals

$25–$50

Total

$73–$98

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 108.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $33 in charging · 1 stop · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 93 1 $32.54 $14.88
Efficient EV 77.5 0 $27.12 $12.40
EV Truck/SUV 124 1 $43.39 $19.83

Gas CO2

108 kg

EV CO2

36 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Joplin, MO

Late night in Joplin on Saturday

Local time

5:32 AM

CDT

Current temp

57°F

Unavailable

Live forecast

Destination

Sainte Genevieve, MO

Late night in Sainte Genevieve on Saturday

Local time

5:32 AM

CDT

Current temp

56°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 3m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Joplin, MO to Sainte Genevieve, MO covers 309.9 miles and takes about 6h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are East 7th Street, Cimarron Road, I 44 East. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 154.9 miles from Joplin, MO. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $48.45 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

The route itself is not hard, but at 6h 3m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.

This route does not have any notably tricky sections. Most of the drive from Joplin, MO to Sainte Genevieve, MO is straightforward, with well-signed roads and simple exits.

The route from Joplin, MO to Sainte Genevieve, MO does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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