Trip from Littlefield, TX to San Antonio, TX

Drive Time

6h 42m

Distance

426.8 mi

Route Type

Turn-heavy local drive

Long day trip

Trip Overview

The drive from Littlefield, TX to San Antonio, TX covers 426.8 miles and takes about 6h 42m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Delano Avenue, Avenue Q, Slaton Road for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $63.50 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

213.4 miles from Littlefield, TX

A natural place for your longest stop of the day.

Drive Character

Expect a 6h 42m drive with frequent turns across 426.8 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.

There are about 34 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

Delano Avenue is one of the defining roads on this drive.

Main Roads

Road	Distance	Duration
Delano Avenue	0 mi	0m
Avenue Q	0 mi	0m
Slaton Road	0 mi	0m
Highway 84	0 mi	0m
Trooper Jerry Don Davis Memorial Highway	0 mi	0m
East 15th Street	0 mi	0m
Ralls Road	0 mi	0m
North Avenue F	0 mi	0m

Longest stretch: Delano Avenue — 0 mi, about 0m

Step-by-Step Directions

1

Start on East Waylon Jennings Boulevard

2

Turn slight right onto Delano Avenue

3

Turn left

4

Merge slight left onto Avenue Q

5

Continue on Slaton Road

6

Continue on East Highway 84

7

Continue on Trooper Jerry Don Davis Memorial Highway

8

Continue on East Highway 84

9

Continue on North US Highway 84

10

Turn left onto East 15th Street

11

Turn right onto Ralls Road

12

Turn straight onto North Avenue F

13

At the end of the road, turn left onto US Highway 84

14

Keep slight left to continue on I 20 East, US 84 East: Abilene

15

Take the exit slight right toward SH 70 South, SH 70 Business: Sweetwater, San Angelo

16

Turn slight left onto Southwest Georgia Avenue

17

Turn right onto Lamar Street

18

Continue on State Highway 70

19

Turn left onto State Highway 153

20

Turn right

21

Turn left

22

At the end of the road, turn right onto Hutchings Avenue

23

Turn left onto South 7th Street

24

Continue on Grassmeyer Street

25

Continue on Ellis Street

26

Take the exit left toward I 10 East: San Antonio

27

Continue straight

28

Keep slight right

29

Keep slight right to continue on McDermott Freeway

30

Take the exit slight right toward Santa Rosa Street, Downtown

31

Turn straight onto North Pecos-La Trinidad

32

Keep slight right to continue on North Pecos-La Trinidad

33

Turn left onto Dolorosa Street

34

Arrive at your destination

When to Leave

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 213.4 miles from Littlefield, TX.

This is a comfortable same-day trip.

Drive Plan

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 94 miles

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 213.4 miles

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Last hour of driving

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Littlefield, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Trip Strategy

Day 1

Settle into the route from Littlefield, TX

This is one driving day of about 426.8 miles and 6h 42m.

Your first comfortable stop window is around 94 miles from Littlefield, TX.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

Best Stop Towns on This Route

These towns line up with the pace of this drive and give you clearer places to stop with a purpose.

Late stop town

Meal stop

Sweetwater, TX

213 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Travel Advice

Arrival Notes

The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Stops Along the Way

Halfway Point

Midpoint

About 213.4 mi from Littlefield, TX

Post, TX

Fuel and coffee

A short stop after about 94 miles helps settle the day before fatigue starts building.

Sweetwater, TX

Meal break

The midpoint is around 213.4 miles from Littlefield, TX, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Fuel Type	$/gal	One Way	Round Trip
regular	$3.78	$63.50	$127.00
midgrade	$4.25	$71.45	$142.89
premium	$4.59	$77.14	$154.29
diesel	$3.99	$67.09	$134.19

Based on 25.4 MPG average. Estimated CO2 emission: 149.3 kg one way.

Frequently Asked Questions

The drive from Littlefield, TX to San Antonio, TX covers 426.8 miles and takes about 6h 42m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Delano Avenue, Avenue Q, Slaton Road. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 213.4 miles from Littlefield, TX. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $63.50 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.