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Trip from Marshall, MO to St. Louis, MO

Compiled by the Trip.ovh editorial team · Last recalculated Apr 17, 2026 · Methodology

Drive Time

3h 39m

Distance

183.8 mi

296 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$29

one way

EV Charging

Unknown

Best Time to Leave

Save up to 38 min
4 AM
3h 27m ★
6 AM
3h 40m
8 AM
4h 5m
10 AM
3h 48m
12 PM
3h 46m
3 PM
3h 50m
5 PM
4h 3m
8 PM
3h 32m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in and county seat of Saline County, Missouri, United States

Marshall, MO

Wikimedia Commons

Trip Overview

This trip from Marshall, MO to St. Louis, MO covers 183.8 miles and should take about 3 hours and 39 minutes, making it a perfect one-day drive. You'll primarily be on the Dwight D. Eisenhower Highway, also known as U.S. Submarine Veterans' Memorial Highway and Avenue of the Saints. With a fuel cost estimated at $29, this journey through the Midwest is straightforward and efficient. The route involves a few turns but is generally manageable for a single day's travel, so an overnight stay isn't necessary.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

91.9 miles from Marshall, MO

A natural place for your longest stop of the day , about 1h 48m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 3h 39m. Total distance: 183.8 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

3h 39m drive, comfortable solo distance.

Scenic Drive

Turn-heavy local drive route profile.

Drive Character

Expect a drive that's about 8% highway, meaning you'll experience a mix of faster travel and more frequent turns. The longest continuous stretch you'll encounter is 82.8 miles on the Dwight D. Eisenhower Highway. This route is characterized as 'turn-heavy,' suggesting that you'll need to stay alert for changes in direction as you progress from Marshall towards St. Louis. It's not a monotonous interstate cruise but rather a more engaging local drive.

This route has more turning and local-road decision points than a simple highway run.
There are about 19 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D. Eisenhower Highway is the longest continuous segment at about 82.8 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.1 miles in near US 65 Bus / North Odell Avenue.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 183.8 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 0.1 miles (US 65 Bus / North Odell Avenue): Navigation decision point; at 143.7 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 143.9 miles (I 64; US 40; US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here.

Critical Maneuvers

5 of 11 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

4
0.1 mi into trip | ~0m in | US 65 Bus / North Odell Avenue

Turn right onto US 65 Bus / North Odell Avenue

Navigation decision point

6
143.7 mi into trip | ~2h 49m in | US 40

Take the exit onto US 40 toward I 64 East, US 40 East, US 61 South: Chesterfield

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 210A Toward I 64 East, US 40 East, US 61 South: Ches...
5
143.9 mi into trip | ~2h 49m in | I 64; US 40; US 61 / Avenue of the Saints

Merge onto I 64; US 40; US 61 / Avenue of the Saints

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight left lanes.
7
183.1 mi into trip | ~3h 37m in

Take the exit toward 14th Street

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 39A Toward 14th Street
5
183.3 mi into trip | ~3h 38m in | South 14th Street

Turn left onto South 14th Street

Lane positioning matters here

Use the left lane.

Main Roads

Road Distance Duration
Dwight D. Eisenhower Highway 82.8 mi 1h 37m
U.S. Submarine Veterans' Memorial Highway 45.7 mi 48m
Avenue of the Saints 27.7 mi 33m
US 65 8.2 mi 9m
Jack Buck Memorial Highway 5.8 mi 7m
Daniel Boone Expressway 5.7 mi 7m
North Odell Avenue 3 mi 7m
Sheriff Roger I. Wilson Memorial Highway 1.9 mi 2m
Longest stretch: Dwight D. Eisenhower Highway — 82.8 mi, about 1h 37m

Turn-by-Turn Driving Directions

Step-by-step road directions between Marshall, MO and St. Louis, MO.

1

Start on US 65 Bus

0.1 mi · 22 sec · East Eastwood Street
2

Turn right onto US 65 Bus

3.0 mi · 7 min · North Odell Avenue
3

Take the ramp

0.1 mi · 16 sec
Toward US 65 South
4

Merge onto US 65

8.2 mi · 9 min · US 65
5

Take the exit

0.3 mi · 48 sec
Toward I 70 East: Saint Louis
6

Merge onto I 70; US 40

23 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
7

Keep slight left at fork onto I 70

22 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
8

Continue on I 70; US 40

1.8 mi · 2 min · Dwight D. Eisenhower Highway
9

Continue on I 70; US 40

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
10

Continue on I 70; US 40

1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
11

Continue on I 70; US 40

81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway
12

Take the exit onto US 40

0.3 mi · 33 sec · US 40
Exit 210A Toward I 64 East, US 40 East, US 61 South: Chesterfield
13

Merge onto I 64; US 40; US 61

28 mi · 33 min · Avenue of the Saints
Use the straight / slight left lanes.
14

Continue on I 64; US 40

5.7 mi · 7 min · Daniel Boone Expressway
Use the straight lane.
15

Continue on I 64; US 40

5.8 mi · 7 min · Jack Buck Memorial Highway
Use the straight / slight right lanes.
16

Take the exit

0.2 mi · 34 sec
Exit 39A Toward 14th Street Use the slight right lane.
17

Turn left onto South 14th Street

0.3 mi · 42 sec · South 14th Street
Use the left lane.
18

Turn right onto Market Street

0.2 mi · 25 sec · Market Street
19

Arrive at destination

Market Street

Trip Plan

Given the 3-hour 39-minute duration, you can easily complete this trip in one day. Leaving Marshall in the morning will give you ample time to reach St. Louis with flexibility for any unscheduled stops. The estimated fuel cost is $29, so plan accordingly. While the drive has a 'turn-heavy' profile, the longest uninterrupted stretch is over 80 miles, offering some periods of consistent travel. Pay attention to signs for the Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, and Avenue of the Saints to navigate smoothly.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 91.9 miles from Marshall, MO, or about 1h 48m into the drive.
The longest continuous stretch on this route runs about 82.8 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 40 miles or 48m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 91.9 miles or 1h 48m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 57m

Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Marshall, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Marshall, MO

This is one driving day of about 183.8 miles and 3h 39m.

Your first comfortable stop window is around 40 miles from Marshall, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D. Eisenhower Highway for about 82.8 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 91.9 mi from Marshall, MO · 1h 48m into the drive

city in St. Charles County, Missouri, United States

Mid-route town

Meal stop

Wentzville, MO

92 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

New Franklin, MO

Fuel and coffee

A short stop after about 40 miles helps settle the day before fatigue starts building.

Montgomery City, MO

Meal break

The midpoint is around 91.9 miles from Marshall, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 82.8 miles.

Arriving in St. Louis, MO

The final approach into St. Louis, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around St. Louis, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$28.74 one way

$57.47 round trip

$3.97/gal 25.4 MPG avg 64 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $31.55 $63.10
premium $4.89 $35.37 $70.74
diesel $5.61 $40.58 $81.16

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$29

Meals

$25–$50

Total

$54–$79

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 64.3 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $19 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 55.1 0 $19.30 $8.82
Efficient EV 46 0 $16.08 $7.35
EV Truck/SUV 73.5 0 $25.73 $11.76

Gas CO2

64 kg

EV CO2

22 kg (66% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Marshall, MO

Late night in Marshall on Friday

Local time

2:21 AM

CDT

Current temp

71°F

Unavailable

Live forecast

Destination

St. Louis, MO

Late night in St. Louis on Friday

Local time

2:21 AM

CDT

Current temp

74°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

3 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

3h 39m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Marshall, MO to St. Louis, MO covers 183.8 miles and takes about 3h 39m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Avenue of the Saints. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 91.9 miles from Marshall, MO. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $28.74 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.

This drive requires moderate attention. Across 183.8 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

The main spots that need attention: at 0.1 miles (US 65 Bus / North Odell Avenue): Navigation decision point; at 143.7 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 143.9 miles (I 64; US 40; US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here.

The route from Marshall, MO to St. Louis, MO does not surface many named destination signs beyond the main corridor.

Data sources

The figures on this page are computed from open government and mapping datasets, not crowdsourced reviews. Distances and geometry come from OSRM over OpenStreetMap. Fuel cost uses EIA weekly regional averages. Full methodology, refresh cadence, and limitations are documented on the methodology page.

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