Embarking on a road trip from Poplar Bluff, MO, to Kansas City, MO, covers 356.1 miles and is estimated to take about 7 hours and 2 minutes of driving time. This drive is primarily a highway-focused experience, with 97% of the route utilizing major roads like US 60 and MO 7. Given its duration, this trip is well-suited for a single day, though you might consider an overnight stop if you prefer a more relaxed pace. The estimated fuel cost for this journey is around $56. You'll be traveling within the Midwest region for the entirety of this route, experiencing a consistent Midwestern landscape.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
178.1 miles from Poplar Bluff, MO
A natural place for your longest stop of the day
, about 3h 31m into the drive
.