The drive from Saint Peters, MO to Kissee Mills, MO covers 258.8 miles and takes about 5h 6m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 44, US 160, MO 100 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 170.7 miles on I 44.
At current regular gas prices, budget about $40.46 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
129.4 miles from Saint Peters, MO
A natural place for your longest stop of the day
, about 2h 36m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 6m. Total distance: 258.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 6m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (89%). Some complex stretches to watch for.
Drive Character
This is a 5h 6m highway drive covering 258.8 miles, with most of the trip on I 44 and US 160. The longest continuous stretch is about 170.7 miles on I 44.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 36 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 44 is the longest continuous segment at about 170.7 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 44 and US 160. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 3 miles in.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 21 significant decision points across 258.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 10.5 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 14.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Critical Maneuvers
5 of 21 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
3 mi into trip|~3m in
Take the exit toward MO K: O'Fallon, Main Street
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 218
Toward MO K: O'Fallon, Main Street
6
10.5 mi into trip|~16m in
Take the ramp toward I 64 East, US 40 East, US 61 South
Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 64 East, US 40 East, US 61 South
7
14.5 mi into trip|~21m in
Take the exit toward Chesterfield Airport Road
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 14
Toward Chesterfield Airport Road
5
23.1 mi into trip|~37m in
Enter roundabout toward MO 100 West: Gray Summit
Roundabout - know your exit number before entering
Toward MO 100 West: Gray Summit
5
36.7 mi into trip|~56m in
Take the exit toward I 44 West, US 50 West: St. Clair
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 44 West, US 50 West: St. Clair
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Saint Peters, MO to Kissee Mills, MO, road signs begin pointing toward Forsyth along the way.
Forsyth
243 mi in|~4h 42m
Main Roads
Road
Distance
Duration
I 44
170.7 mi
3h 3m
US 160
15.5 mi
23m
MO 100
13.3 mi
18m
American Legion Memorial Highway
12.1 mi
13m
US Highway 65
12 mi
13m
Schoolcraft Freeway
11 mi
13m
MO K
6.5 mi
11m
MO 109
4.7 mi
7m
Longest stretch:
I 44
— 170.7 mi, about 3h 3m
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Peters, MO and Kissee Mills, MO.
1
Start on I 70
3.0 mi·3 min·I 70
Use the straight / slight right lanes.
2
Take the exit
390 ft·8 sec
Exit 218Toward MO K: O'Fallon, Main StreetUse the slight right lane.
3
Turn straight onto East Terra Lane
0.9 mi·1 min·East Terra Lane
Use the straight lane.
4
Turn slight left
61 ft·1 sec
5
Continue on MO K
3.1 mi·5 min·MO K
Use the left lane.
6
Continue on MO K
3.4 mi·5 min·MO K
Use the straight lane.
7
Take the ramp
0.3 mi·21 sec
Toward I 64 East, US 40 East, US 61 SouthUse the slight right lane.
8
Merge onto I 64; US 40; US 61
3.7 mi·4 min·Avenue of the Saints
9
Take the exit
0.5 mi·57 sec
Exit 14Toward Chesterfield Airport RoadUse the slight right lane.
10
Continue on Chesterfield Airport Road
361 ft·6 sec·Chesterfield Airport Road
11
Turn right
211 ft·5 sec
Toward Olive Street Road
12
Turn right onto Olive Street Road
0.9 mi·1 min·Olive Street Road
13
Continue on North Eatherton Road
2.4 mi·4 min·North Eatherton Road
14
Enter roundabout onto MO 109
70 ft·1 sec·MO 109
15
Continue on MO 109
4.3 mi·6 min·MO 109
16
Enter roundabout onto MO 109
94 ft·2 sec·MO 109
17
Continue on MO 109
0.4 mi·44 sec·MO 109
18
Enter roundabout
76 ft·1 sec
Toward MO 100 West: Gray Summit
19
Continue
0.2 mi·32 sec
Toward MO 100 West: Gray Summit
20
Merge onto MO 100
13 mi·18 min·MO 100
21
Take the exit
0.2 mi·14 sec
Toward I 44 West, US 50 West: St. Clair
22
Merge onto I 44; US 50
171 mi·3 hr 3 min·I 44; US 50
Use the straight lane.
23
Take the exit
0.3 mi·48 sec
Exit 82AToward US 65 South: Branson
24
Merge onto US 65
11 mi·13 min·Schoolcraft Freeway
Use the straight / slight right lanes.
25
Continue on US 65
11 mi·12 min·American Legion Memorial Highway
26
Continue on US 65
12 mi·13 min·US Highway 65
27
Continue on US 65
1.2 mi·1 min·American Legion Memorial Highway
28
Take the exit
0.2 mi·32 sec
Toward US 160: Reed Springs Junction, Forsyth
29
Turn left onto US 160
4.3 mi·6 min·US 160
30
Turn slight left onto US 160; MO 176
7.2 mi·10 min·US 160; MO 176
31
Enter roundabout onto US 160; MO 76
122 ft·2 sec·US 160; MO 76
32
Continue on US 160; MO 76
76 ft·1 sec·US 160; MO 76
33
Turn straight onto US 160; MO 76
2.9 mi·4 min·US 160; MO 76
34
Continue on US 160
1.1 mi·1 min·US 160
35
Turn slight right onto MO O
97 ft·2 sec·MO O
36
Arrive at destination
MO O
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 129.4 miles from Saint Peters, MO, or about 2h 36m into the drive.
The longest continuous stretch on this route runs about 170.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 57 miles or 1h 18m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 129.4 miles or 2h 36m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 6m
Traffic, exits, and arrival timing usually matter more near Kissee Mills, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Peters, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Peters, MO
This is one driving day of about 258.8 miles and 5h 6m.
Your first comfortable stop window is around 57 miles from Saint Peters, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 44 for about 170.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 129.4 mi from Saint Peters, MO
· 2h 36m into the drive
The midpoint is around 129.4 miles from Saint Peters, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before I 44 if your tank is already low. That segment runs about 170.7 miles.
Arriving in Kissee Mills, MO
The final approach into Kissee Mills, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Kissee Mills, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Wilson's Creek National Battlefield
National Battlefield
Wilson's Creek was the first major Civil War battle fought west of the Mississippi River, and where the first Union general was killed in action. The costly Southern victory on August 10, 1861, focuse...
11 mi from route
~27 min detour
Free
near mile 214.2
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
26 mi from route
~65 min detour
$19
near mile 17.8
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$40.46 one way
$80.92 round trip
$3.97/gal25.4 MPG avg91 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$44.42
$88.85
premium
$4.89
$49.80
$99.61
diesel
$5.61
$57.14
$114.28
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$40
Meals
$25–$50
Total
$65–$90
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 90.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $27 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
77.6
0
$27.17
$12.42
Efficient EV
64.7
0
$22.65
$10.35
EV Truck/SUV
103.5
1
$36.23
$16.56
Gas CO2
91 kg
EV CO2
30 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Saint Peters, MO
Afternoon
in Saint Peters on Thursday
Local time
12:34 PM
CDT
Current temp
57°F
Unavailable
Live forecast
Destination
Kissee Mills, MO
Afternoon
in Kissee Mills on Thursday
Local time
12:34 PM
CDT
Current temp
77°F
Unavailable
Live forecast
75°F
Cuba, MO
129 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
20 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 6m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Saint Peters, MO to Kissee Mills, MO covers 258.8 miles and takes about 5h 6m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 44, US 160, MO 100. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 129.4 miles from Saint Peters, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $40.46 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 21 significant decision points across 258.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 10.5 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 14.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
On the drive from Saint Peters, MO to Kissee Mills, MO, road signs begin pointing toward Forsyth along the way.
Yes. Nearby national parks include Wilson's Creek National Battlefield and Gateway Arch National Park.
