The drive from Shannon, MS to Biloxi, MS covers 297.3 miles and takes about 5h 47m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 59, US Highway 45 Aiternate, US Highway 45 Alternate for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 88.7 miles on I 59.
At current regular gas prices, budget about $44.90 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
148.7 miles from Shannon, MS
A natural place for your longest stop of the day
, about 2h 55m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 47m. Total distance: 297.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 47m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (98%). Some complex stretches to watch for.
Drive Character
This is a 5h 47m highway drive covering 297.3 miles, with most of the trip on I 59 and US Highway 45 Aiternate. The longest continuous stretch is about 88.7 miles on I 59.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 30 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 59 is the longest continuous segment at about 88.7 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 59 and US Highway 45 Aiternate. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 137.2 miles in near I 59.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 297.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 137.2 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 225.9 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 229.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 17 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
137.2 mi into trip|~2h 43m in|I 59
Keep slight left at fork onto I 59 toward I 59 South: Laurel, New Orleans
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward I 59 South: Laurel, New Orleans
7
225.9 mi into trip|~4h 19m in|US 98
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 98 East: Lucedale, Mobile
7
229.1 mi into trip|~4h 23m in
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
229.4 mi into trip|~4h 24m in
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Multi Purpose Center, Hattiesburg
6
229.6 mi into trip|~4h 24m in|US 49
Turn right onto US 49
Lane positioning matters here
Use the straight lane.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Shannon, MS and Biloxi, MS, road signs point toward New Orleans, Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.
New Orleans
137.2 mi in|~2h 43m|via I 59
Mobile
225.9 mi in|~4h 19m|via US 98
Gulfport
229.1 mi in|~4h 23m
Mississippi Gulf Coast
229.1 mi in|~4h 23m
Multi Purpose Center
229.4 mi in|~4h 24m
Hattiesburg
229.4 mi in|~4h 24m
Main Roads
Road
Distance
Duration
I 59
88.7 mi
1h 36m
US Highway 45 Aiternate
60.6 mi
1h 9m
US Highway 45 Alternate
54.7 mi
1h 6m
US 49
41.9 mi
49m
Biloxi-D'Iberville Scenic Expressway
20.5 mi
24m
I 20
8.1 mi
9m
US 45 ALT
7.2 mi
8m
US 45
3.9 mi
4m
Longest stretch:
I 59
— 88.7 mi, about 1h 36m
Turn-by-Turn Driving Directions
Step-by-step road directions between Shannon, MS and Biloxi, MS.
1
Start on Boyd Avenue
73 ft·5 sec·Boyd Avenue
2
Turn right onto Broad Street
0.4 mi·1 min·Broad Street
3
Turn left onto North Collins
124 ft·7 sec·North Collins
4
Turn right onto MS 145
433 ft·6 sec·Noah Curtis Street
5
Take the ramp
0.4 mi·1 min
Toward US 45 Alternate South: West Point
6
Merge onto US 45 ALT
1.2 mi·1 min·Martin Luther King Drive
7
Continue on US 45 ALT
1.4 mi·1 min·US 45 ALT
8
Continue on US 45 ALT
2.2 mi·2 min·US 45 ALT
9
Continue on US 45 ALT
1.5 mi·1 min·US 45 ALT
10
Continue on US 45 ALT
0.7 mi·49 sec·US 45 ALT
11
Continue on US 45 ALT
1.4 mi·1 min·US 45 ALT
12
Continue on US 45 ALT
55 mi·1 hr 6 min·US Highway 45 Alternate
Use the straight lane.
13
Continue on US 45
61 mi·1 hr 9 min·US Highway 45 Aiternate
14
Keep slight right at fork onto US 45
3.9 mi·4 min·US 45
15
Take the exit
0.5 mi·1 min
Toward I 59 South, I 20 West: Meridian
16
Merge onto I 20; I 59
6.3 mi·7 min·I 20; I 59
Use the straight / slight right lanes.
17
Continue on I 20; I 59; US 80
1.8 mi·2 min·I 20; I 59; US 80
Use the straight lane.
18
Keep slight left at fork onto I 59
89 mi·1 hr 36 min·I 59
Toward I 59 South: Laurel, New OrleansUse the slight left / slight right lanes.
19
Take the exit onto US 98
3.2 mi·4 min·US 98
Toward US 98 East: Lucedale, MobileUse the straight / slight right lanes.
20
Take the exit
0.3 mi·44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf CoastUse the straight / slight right lanes.
21
Keep slight left at fork
0.2 mi·27 sec
Toward Multi Purpose Center, HattiesburgUse the slight left / slight right lanes.
22
Turn right onto US 49
42 mi·49 min·US 49
Use the straight lane.
23
Take the exit
0.8 mi·1 min
Toward MS 67 South: D'Iberville, Biloxi
24
Continue on MS 67
20 mi·24 min·Biloxi-D'Iberville Scenic Expressway
25
Continue on I 110
3.2 mi·4 min·I 110
26
Take the exit
0.4 mi·47 sec
Exit 1cToward Division Street
27
Turn left onto Division Street
0.6 mi·1 min·Division Street
28
Turn right onto Main Street
0.5 mi·1 min·Main Street
29
Turn left onto Howard Avenue
91 ft·3 sec·Howard Avenue
30
Arrive at destination
Howard Avenue
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 148.7 miles from Shannon, MS, or about 2h 55m into the drive.
The longest continuous stretch on this route runs about 88.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 65 miles or 1h 19m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 148.7 miles or 2h 55m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 41m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Shannon, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Shannon, MS
This is one driving day of about 297.3 miles and 5h 47m.
Your first comfortable stop window is around 65 miles from Shannon, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 59 for about 88.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 148.7 mi from Shannon, MS
· 2h 55m into the drive
The midpoint is around 148.7 miles from Shannon, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before I 59 if your tank is already low. That segment runs about 88.7 miles.
Arriving in Biloxi, MS
The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Tupelo National Battlefield
National Battlefield
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $31 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
89.2
1
$31.22
$14.27
Efficient EV
74.3
0
$26.01
$11.89
EV Truck/SUV
118.9
1
$41.62
$19.03
Gas CO2
104 kg
EV CO2
35 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Shannon, MS
Afternoon
in Shannon on Friday
Local time
3:44 PM
CDT
Current temp
52°F
Unavailable
Live forecast
Destination
Biloxi, MS
Afternoon
in Biloxi on Friday
Local time
3:44 PM
CDT
Current temp
61°F
Unavailable
Live forecast
79°F
Newton, MS
149 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 47m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Shannon, MS to Biloxi, MS covers 297.3 miles and takes about 5h 47m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 59, US Highway 45 Aiternate, US Highway 45 Alternate. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 148.7 miles from Shannon, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $44.90 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 17 significant decision points across 297.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 137.2 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 225.9 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 229.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Shannon, MS and Biloxi, MS, road signs point toward New Orleans, Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
