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Trip from St. Louis, MO to Greenfield, MO

Last recalculated Apr 16, 2026

Drive Time

4h 52m

Distance

253.1 mi

407 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$40

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
4h 39m ★
6 AM
4h 52m
8 AM
5h 19m
10 AM
5h 2m
12 PM
4h 59m
3 PM
5h 3m
5 PM
5h 18m
8 PM
4h 44m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Greenfield, MO, MO

Greenfield, MO

Orhan Pergel

Trip Overview

The drive from St. Louis, MO to Greenfield, MO covers 253.1 miles and takes about 4h 52m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Henry Shaw Ozark Corridor, US 160, Olympian Boulevard for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 201.4 miles on Henry Shaw Ozark Corridor. At current regular gas prices, budget about $39.57 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

126.5 miles from St. Louis, MO

A natural place for your longest stop of the day , about 2h 22m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 52m. Total distance: 253.1 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 52m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (8%). Straightforward navigation.

Scenic Drive

Turn-heavy local drive route profile with national parks nearby.

Drive Character

Expect a 4h 52m drive with frequent turns across 253.1 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Henry Shaw Ozark Corridor is the longest continuous segment at about 201.4 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 215.8 miles in.

Driving Effort 3/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

This is a straightforward 4h 52m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: at 215.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 219.5 miles (US 160): Roundabout - know your exit number before entering; at 220.8 miles (US 160): Roundabout - know your exit number before entering.

Critical Maneuvers

5 of 10 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
215.8 mi into trip | ~3h 59m in

Take the exit toward US 160: West Bypass, Willard

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 75 Toward US 160: West Bypass, Willard
4
219.5 mi into trip | ~4h 4m in | US 160

Enter roundabout onto US 160

Roundabout - know your exit number before entering

4
220.8 mi into trip | ~4h 6m in | US 160

Enter roundabout onto US 160

Roundabout - know your exit number before entering

4
221.5 mi into trip | ~4h 7m in | US 160 / Olympian Boulevard

Enter roundabout onto US 160 / Olympian Boulevard

Roundabout - know your exit number before entering

6
252.8 mi into trip | ~4h 51m in | Talbutt Street

At end of road, turn left onto Talbutt Street

Complex interchange - multiple decisions in a short stretch

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from St. Louis, MO to Greenfield, MO, road signs begin pointing toward Willard along the way.

Willard

215.8 mi in | ~3h 59m

Main Roads

Road Distance Duration
Henry Shaw Ozark Corridor 201.4 mi 3h 39m
US 160 19.5 mi 26m
Olympian Boulevard 17 mi 23m
Police Officer Ernest M. Brockman Sr. Memorial Highway 3.5 mi 4m
Officer Michael Barwick Memorial Highway 3.5 mi 4m
Police Officer Robert Stanze Memorial Highway 2.7 mi 3m
Officer David Haynes Memorial Highway 2.3 mi 3m
South Jefferson Avenue 1.2 mi 2m
Longest stretch: Henry Shaw Ozark Corridor — 201.4 mi, about 3h 39m

Turn-by-Turn Driving Directions

Step-by-step road directions between St. Louis, MO and Greenfield, MO.

1

Start on Market Street

1.0 mi · 2 min · Market Street
2

Turn left onto South Jefferson Avenue

1.2 mi · 2 min · South Jefferson Avenue
3

Take the ramp

0.2 mi · 17 sec
Toward I 44 West
4

Merge onto I 44

2.3 mi · 3 min · Officer David Haynes Memorial Highway
5

Continue on I 44

3.5 mi · 4 min · Officer Michael Barwick Memorial Highway
6

Continue on I 44

2.7 mi · 3 min · Police Officer Robert Stanze Memorial Highway
7

Continue on I 44

3.5 mi · 4 min · Police Officer Ernest M. Brockman Sr. Memorial Highway
8

Continue on I 44; US 50

201 mi · 3 hr 39 min · Henry Shaw Ozark Corridor
Use the straight / slight right lanes.
9

Take the exit

0.3 mi · 33 sec
Exit 75 Toward US 160: West Bypass, Willard
10

Turn right onto US 160

3.5 mi · 4 min · US 160
11

Enter roundabout onto US 160

133 ft · 5 sec · US 160
12

Continue on US 160

1.3 mi · 1 min · US 160
13

Enter roundabout onto US 160

135 ft · 4 sec · US 160
14

Continue on US 160

0.6 mi · 54 sec · US 160
15

Enter roundabout onto US 160

130 ft · 4 sec · Olympian Boulevard
16

Continue on US 160

17 mi · 23 min · Olympian Boulevard
17

Turn straight onto US 160

14 mi · 19 min · US 160
18

Turn left onto Lilly Street

0.2 mi · 54 sec · Lilly Street
19

At end of road, turn left onto Talbutt Street

183 ft · 9 sec · Talbutt Street
20

Turn right onto North Allison Avenue

0.3 mi · 1 min · North Allison Avenue
21

Arrive at destination

South Allison Avenue

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 126.5 miles from St. Louis, MO, or about 2h 22m into the drive.
The longest continuous stretch on this route runs about 201.4 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 56 miles or 1h 5m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 126.5 miles or 2h 22m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 50m

Traffic, exits, and arrival timing usually matter more near Greenfield, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving St. Louis, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from St. Louis, MO

This is one driving day of about 253.1 miles and 4h 52m.

Your first comfortable stop window is around 56 miles from St. Louis, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Henry Shaw Ozark Corridor for about 201.4 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 126.5 mi from St. Louis, MO · 2h 22m into the drive

city in and the county seat of Pulaski County, Missouri, United States

Mid-route town

Meal stop

Waynesville, MO

127 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Byrnes Mill, MO

Fuel and coffee

A short stop after about 56 miles helps settle the day before fatigue starts building.

Waynesville, MO

Meal break

The midpoint is around 126.5 miles from St. Louis, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Henry Shaw Ozark Corridor if your tank is already low. That segment runs about 201.4 miles.

Arriving in Greenfield, MO

The final approach into Greenfield, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Greenfield, MO.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Gateway Arch National Park

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

0 mi from route ~1 min detour $19
View on nps.gov
Wilson's Creek National Battlefield

Wilson's Creek National Battlefield

National Battlefield

Wilson's Creek was the first major Civil War battle fought west of the Mississippi River, and where the first Union general was killed in action. The costly Southern victory on August 10, 1861, focuse...

12 mi from route ~29 min detour Free near mile 218.2
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$39.57 one way

$79.14 round trip

$3.97/gal 25.4 MPG avg 89 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $43.45 $86.89
premium $4.89 $48.71 $97.41
diesel $5.61 $55.88 $111.76

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$40

Meals

$25–$50

Total

$65–$90

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 88.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $27 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 75.9 0 $26.58 $12.15
Efficient EV 63.3 0 $22.15 $10.12
EV Truck/SUV 101.2 1 $35.43 $16.20

Gas CO2

89 kg

EV CO2

30 kg (66% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

St. Louis, MO

Evening in St. Louis on Thursday

Local time

6:14 PM

CDT

Current temp

74°F

Unavailable

Live forecast

Destination

Greenfield, MO

Evening in Greenfield on Thursday

Local time

6:14 PM

CDT

Current temp

54°F

Unavailable

Live forecast

76°F

Waynesville, MO

127 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

20 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 52m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from St. Louis, MO to Greenfield, MO covers 253.1 miles and takes about 4h 52m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Henry Shaw Ozark Corridor, US 160, Olympian Boulevard. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 126.5 miles from St. Louis, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $39.57 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a straightforward 4h 52m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: at 215.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 219.5 miles (US 160): Roundabout - know your exit number before entering; at 220.8 miles (US 160): Roundabout - know your exit number before entering.
On the drive from St. Louis, MO to Greenfield, MO, road signs begin pointing toward Willard along the way.
Yes. Nearby national parks include Gateway Arch National Park and Wilson's Creek National Battlefield.

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Explore More

Return Trip

Greenfield, MO to St. Louis, MO

Plan the drive back the other way.

253.2 mi 4h 52m

Explore more options from St. Louis, MO or browse trips ending in Greenfield, MO.

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Explore maps for St. Louis, MO or Greenfield, MO on MapSof.net.