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Trip from Tupelo, MS to Carthage, MS

Last recalculated Apr 16, 2026

Drive Time

2h 49m

Distance

142 mi

229 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$21

one way

EV Charging

Unknown

Best Time to Leave

Save up to 32 min
4 AM
2h 39m ★
6 AM
2h 50m
8 AM
3h 11m
10 AM
2h 57m
12 PM
2h 55m
3 PM
2h 58m
5 PM
3h 10m
8 PM
2h 43m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Tupelo, MS, MS

Tupelo, MS

Wikimedia Commons

Downtown Carthage, MS, MS

Carthage, MS

Anton Ivanov

Trip Overview

This straightforward 142-mile drive from Tupelo, MS, to Carthage, MS, is easily managed as a single-day trip, taking approximately 2 hours and 49 minutes. With 91% of the journey on highways, you'll spend most of your time on major roads like MS 25 and US Highway 45 Alternate. The estimated fuel cost for this Southeast to Southeast route is around $21, making it an economical choice for a quick getaway. This route offers a focused highway experience, perfect for those who prefer covering ground efficiently. Given the relatively short duration, you can comfortably complete this drive in one go without needing an overnight stop.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

71 miles from Tupelo, MS

A natural place for your longest stop of the day , about 1h 26m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 49m. Total distance: 142 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

2h 49m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (91%). Some complex stretches to watch for.

Drive Character

Expect a predominantly highway-focused experience on this 142-mile route. You'll be navigating main roads including MS 25 and US Highway 45 Alternate for the vast majority of your journey, with 91% of the trip taking place on highways. The drive features a significant uninterrupted stretch of 84 miles on MS 25, indicating long periods of consistent travel. While primarily highway, the route may offer a mix of speeds and road types as you transition between different sections and approach your destination. This profile suggests a journey where forward momentum is key.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 24 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MS 25 is the longest continuous segment at about 84 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on MS 25 and US Highway 45 Alternate. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near Court Street.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 142 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: near the start (Court Street): Navigation decision point; at 0.1 miles (North Front Street): Navigation decision point; at 0.1 miles (East Main Street): Lane positioning matters here.

Critical Maneuvers

5 of 11 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0 mi into trip | ~0m in | Court Street

Turn right onto Court Street

Navigation decision point

4
0.1 mi into trip | ~0m in | North Front Street

Turn right onto North Front Street

Navigation decision point

5
0.1 mi into trip | ~0m in | East Main Street

Turn left onto East Main Street

Lane positioning matters here

Use the left lane.
5
54.9 mi into trip | ~1h 7m in | MS 25

Take the exit onto MS 25 toward US 82 West, MS 12 West, MS 25 South: Starkville

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Toward US 82 West, MS 12 West, MS 25 South: Sta...
4
66.6 mi into trip | ~1h 20m in | MS 25

Take the exit onto MS 25 toward MS 25 South: Louisville

Exit ramp - move to the correct lane early

Toward MS 25 South: Louisville

Main Roads

Road Distance Duration
MS 25 84 mi 1h 36m
US Highway 45 Alternate 35.7 mi 43m
Martin Luther King Drive 8.7 mi 10m
US 45 ALT 7.2 mi 8m
MS 35 2.7 mi 4m
Martin Luther King, Junior Drive 2.3 mi 2m
East Main Street 0.5 mi 1m
Court Street <0.1 mi <1m
Longest stretch: MS 25 — 84 mi, about 1h 36m

Turn-by-Turn Driving Directions

Step-by-step road directions between Tupelo, MS and Carthage, MS.

1

Start on North Spring Street

68 ft · 5 sec · North Spring Street
2

Turn right onto Court Street

317 ft · 16 sec · Court Street
3

Turn right onto North Front Street

287 ft · 15 sec · North Front Street
4

Turn left onto East Main Street

0.5 mi · 1 min · East Main Street
Use the left lane.
5

Take the ramp

0.4 mi · 55 sec
6

Merge onto US 45; MS 6

1.0 mi · 1 min · Martin Luther King Drive
7

Continue on US 45; MS 6

2.3 mi · 2 min · Martin Luther King, Junior Drive
8

Continue on US 45; US 278

7.7 mi · 8 min · Martin Luther King Drive
9

Continue on US 45 ALT

1.4 mi · 1 min · US 45 ALT
10

Continue on US 45 ALT

2.2 mi · 2 min · US 45 ALT
11

Continue on US 45 ALT

1.5 mi · 1 min · US 45 ALT
12

Continue on US 45 ALT

0.7 mi · 49 sec · US 45 ALT
13

Continue on US 45 ALT

1.4 mi · 1 min · US 45 ALT
14

Continue on US 45 ALT

36 mi · 43 min · US Highway 45 Alternate
Use the straight lane.
15

Take the exit onto MS 25

12 mi · 13 min · MS 25
Toward US 82 West, MS 12 West, MS 25 South: Starkville
16

Take the exit onto MS 25

5.0 mi · 6 min · MS 25
Toward MS 25 South: Louisville
17

Continue on MS 25

1.9 mi · 2 min · MS 25
Use the left lane.
18

Keep slight right at fork onto MS 25

25 mi · 28 min · MS 25
19

Take the exit onto MS 25

40 mi · 46 min · MS 25
20

Take the exit

0.3 mi · 48 sec
21

Keep slight left at fork

207 ft · 7 sec
22

Turn left

121 ft · 3 sec
23

Turn slight left onto MS 35

2.7 mi · 4 min · MS 35
24

Arrive at destination

MS 35

Trip Plan

For this approximately 2 hour and 49 minute drive, departing in the morning is recommended to allow for flexibility. With only one recommended stop and a fuel cost of around $21, you can easily manage this trip without extensive planning. The longest stretch without a major change is 84 miles on MS 25, so consider taking a brief break before or during this segment to stay refreshed. Since this is a manageable 142-mile route, you have the advantage of being able to adjust your pace as needed. Keep an eye on your fuel gauge, especially before embarking on that 84-mile stretch on MS 25.

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 71 miles from Tupelo, MS, or about 1h 26m into the drive.
The longest continuous stretch on this route runs about 84 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 31 miles or 38m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 71 miles or 1h 26m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 18m

Traffic, exits, and arrival timing usually matter more near Carthage, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Tupelo, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Tupelo, MS

This is one driving day of about 142 miles and 2h 49m.

Your first comfortable stop window is around 31 miles from Tupelo, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS 25 for about 84 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 71 mi from Tupelo, MS · 1h 26m into the drive

city in Mississippi, United States

Mid-route town

Meal stop

Starkville, MS

71 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Aberdeen, MS

Fuel and coffee

A short stop after about 31 miles helps settle the day before fatigue starts building.

Starkville, MS

Meal break

The midpoint is around 71 miles from Tupelo, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before MS 25 if your tank is already low. That segment runs about 84 miles.

Arriving in Carthage, MS

The final approach into Carthage, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Carthage, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$21.45 one way

$42.89 round trip

$3.84/gal 25.4 MPG avg 50 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $23.54 $47.08
premium $4.56 $25.49 $50.97
diesel $5.61 $31.35 $62.70

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$21

Meals

$25–$50

Total

$46–$71

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 49.7 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $15 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 42.6 0 $14.91 $6.82
Efficient EV 35.5 0 $12.42 $5.68
EV Truck/SUV 56.8 0 $19.88 $9.09

Gas CO2

50 kg

EV CO2

17 kg (66% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Tupelo, MS

Morning in Tupelo on Thursday

Local time

10:57 AM

CDT

Current temp

78°F

Unavailable

Live forecast

Destination

Carthage, MS

Morning in Carthage on Thursday

Local time

10:57 AM

CDT

Current temp

59°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

19 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 49m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Tupelo, MS to Carthage, MS covers 142 miles and takes about 2h 49m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MS 25, US Highway 45 Alternate, Martin Luther King Drive. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 71 miles from Tupelo, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $21.45 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This drive requires moderate attention. Across 142 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: near the start (Court Street): Navigation decision point; at 0.1 miles (North Front Street): Navigation decision point; at 0.1 miles (East Main Street): Lane positioning matters here.
The route from Tupelo, MS to Carthage, MS does not surface many named destination signs beyond the main corridor.

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