The drive from Walnut Grove, MS to Biloxi, MS covers 314.1 miles and takes about 6h 50m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Highway 49 South, US 49, North Martin Luther King Drive for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 80.3 miles on Highway 49 South.
At current regular gas prices, budget about $47.44 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
157 miles from Walnut Grove, MS
A natural place for your longest stop of the day
, about 3h 38m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 50m. Total distance: 314.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 50m drive, plan rest stops for pacing.
Drive Character
This is a 6h 50m highway drive covering 314.1 miles, with most of the trip on Highway 49 South and US 49. The longest continuous stretch is about 80.3 miles on Highway 49 South.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 39 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Highway 49 South is the longest continuous segment at about 80.3 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Highway 49 South and US 49. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 151.5 miles in near I 20; US 49.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 25 significant decision points across 314.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 151.5 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 234.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 242.7 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 25 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
151.5 mi into trip|~3h 31m in|I 20; US 49
Keep slight right at fork onto I 20; US 49 toward Meridian, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Meridian, Hattiesburg
7
234.6 mi into trip|~5h 13m in
Take the exit toward I 59 South: New Orleans, Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 59 South: New Orleans, Gulf Coast
7
242.7 mi into trip|~5h 22m in|US 98
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 98 East: Lucedale, Mobile
7
245.9 mi into trip|~5h 26m in
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
246.2 mi into trip|~5h 27m in
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Multi Purpose Center, Hattiesburg
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Walnut Grove, MS and Biloxi, MS, road signs point toward Meridian, Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast and Mobile - among others.
Meridian
151.5 mi in|~3h 31m|via I 20; US 49
Hattiesburg
151.5 mi in|~3h 31m|via I 20; US 49
Richland
152.1 mi in|~3h 31m|via US 49
Gulf Coast
234.6 mi in|~5h 13m
Mississippi Gulf Coast
235 mi in|~5h 13m|via I 59
Mobile
242.7 mi in|~5h 22m|via US 98
Gulfport
245.9 mi in|~5h 26m
Multi Purpose Center
246.2 mi in|~5h 27m
Main Roads
Road
Distance
Duration
Highway 49 South
80.3 mi
1h 37m
US 49
53.4 mi
1h 4m
North Martin Luther King Drive
46.2 mi
55m
Jerry Clower Boulevard
38.8 mi
47m
US 61
34.8 mi
44m
Biloxi-D'Iberville Scenic Expressway
20.5 mi
24m
MS 448
13.5 mi
23m
Lance Corporal Roy M Wheat Memorial Highway
7.7 mi
8m
Longest stretch:
Highway 49 South
— 80.3 mi, about 1h 37m
Turn-by-Turn Driving Directions
Step-by-step road directions between Walnut Grove, MS and Biloxi, MS.
1
Start on this road
0.8 mi·3 min·this road
2
Continue on Alligator - Rena Lara Road
1.1 mi·4 min·Alligator - Rena Lara Road
3
Continue on Rena Lara Road
1.5 mi·5 min·Rena Lara Road
4
Turn left onto Buzzard Roost Road
1.0 mi·4 min·Buzzard Roost Road
5
Turn right onto North New Africa Road
0.3 mi·1 min·North New Africa Road
6
Continue on Jenkins Street
0.4 mi·1 min·Jenkins Street
7
Continue on Butler Street
0.2 mi·40 sec·Butler Street
8
Continue on MS 802
0.7 mi·2 min·Lake Street
9
Take the ramp
344 ft·9 sec
10
Merge onto US 61; US 278
35 mi·44 min·US 61; US 278
11
Turn left onto MS 448
1.1 mi·2 min·East Peeler Avenue
12
Turn right onto MS 448
13 mi·23 min·MS 448
13
Turn left onto US 82
0.7 mi·1 min·US 82
14
Turn right onto US 49W
46 mi·55 min·North Martin Luther King Drive
15
Keep slight right at fork onto US 49W
0.5 mi·53 sec·US 49W
Toward US 49 South: Jackson
16
Merge onto US 49
39 mi·47 min·Jerry Clower Boulevard
17
Take the exit onto US 49
4.9 mi·5 min·US 49
18
Keep slight left at fork onto US 49
3.8 mi·5 min·US 49
19
Merge onto I 20; I 55; US 49
1.1 mi·1 min·I 20; I 55; US 49
20
Keep slight right at fork onto I 20; US 49
347 ft·4 sec·I 20; US 49
Toward Meridian, Hattiesburg
21
Take the exit onto US 49
0.6 mi·42 sec·US 49
Toward Hattiesburg
22
Keep slight right at fork onto US 49
0.7 mi·1 min·US 49
Toward Richland, Hattiesburg
23
Merge onto US 49
80 mi·1 hr 37 min·Highway 49 South
Use the straight lane.
24
Continue on US 49; MS 42
0.4 mi·35 sec·US 49; MS 42
Use the straight lane.
25
Continue on US 49; MS 42
1.1 mi·1 min·US 49; MS 42
Use the straight lane.
26
Take the exit
0.4 mi·36 sec
Toward I 59 South: New Orleans, Gulf CoastUse the slight right lane.
27
Merge onto I 59
7.7 mi·8 min·Lance Corporal Roy M Wheat Memorial Highway
Toward Mississippi Gulf CoastUse the straight lane.
28
Take the exit onto US 98
3.2 mi·4 min·US 98
Toward US 98 East: Lucedale, MobileUse the straight / slight right lanes.
29
Take the exit
0.3 mi·44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf CoastUse the straight / slight right lanes.
30
Keep slight left at fork
0.2 mi·27 sec
Toward Multi Purpose Center, HattiesburgUse the slight left / slight right lanes.
31
Turn right onto US 49
42 mi·49 min·US 49
Use the straight lane.
32
Take the exit
0.8 mi·1 min
Toward MS 67 South: D'Iberville, Biloxi
33
Continue on MS 67
20 mi·24 min·Biloxi-D'Iberville Scenic Expressway
34
Continue on I 110
3.2 mi·4 min·I 110
35
Take the exit
0.4 mi·47 sec
Exit 1cToward Division Street
36
Turn left onto Division Street
0.6 mi·1 min·Division Street
37
Turn right onto Main Street
0.5 mi·1 min·Main Street
38
Turn left onto Howard Avenue
91 ft·3 sec·Howard Avenue
39
Arrive at destination
Howard Avenue
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 157 miles from Walnut Grove, MS, or about 3h 38m into the drive.
The longest continuous stretch on this route runs about 80.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 69 miles or 1h 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 157 miles or 3h 38m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 40m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Walnut Grove, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Walnut Grove, MS
This is one driving day of about 314.1 miles and 6h 50m.
Your first comfortable stop window is around 69 miles from Walnut Grove, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Highway 49 South for about 80.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 157 mi from Walnut Grove, MS
· 3h 38m into the drive
The midpoint is around 161.5 miles from Walnut Grove, MS, which is a good place for a longer meal and fuel stop.
Arriving in Biloxi, MS
The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
3 mi from route
~8 min detour
Free
near mile 140.8
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
22 mi from route
~55 min detour
Free
near mile 10.8
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$47.44 one way
$94.87 round trip
$3.84/gal25.4 MPG avg110 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$52.07
$104.15
premium
$4.56
$56.38
$112.75
diesel
$5.61
$69.35
$138.70
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$47
Meals
$25–$50
Total
$72–$97
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 109.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $33 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
94.2
1
$32.98
$15.08
Efficient EV
78.5
0
$27.48
$12.56
EV Truck/SUV
125.6
1
$43.97
$20.10
Gas CO2
110 kg
EV CO2
37 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Walnut Grove, MS
Morning
in Walnut Grove on Saturday
Local time
10:31 AM
CDT
Current temp
56°F
Unavailable
Live forecast
Destination
Biloxi, MS
Morning
in Biloxi on Saturday
Local time
10:31 AM
CDT
Current temp
61°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
5 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 50m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Walnut Grove, MS to Biloxi, MS covers 314.1 miles and takes about 6h 50m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Highway 49 South, US 49, North Martin Luther King Drive. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 157 miles from Walnut Grove, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $47.44 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 25 significant decision points across 314.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 151.5 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 234.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 242.7 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Walnut Grove, MS and Biloxi, MS, road signs point toward Meridian, Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast and Mobile - among others.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
