Trip from Waynesboro, MS to Meridian, MS

Drive Time

1h 6m

Distance

52.2 mi

84 km

Drive Score

7/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$8

one way

Downtown Meridian, MS, MS

Photo: RDNE Stock project

Trip Overview

If you are planning to travel from Waynesboro to Meridian, you are looking at a straightforward 52.2-mile trek through the heart of Southeast Mississippi. This drive typically takes about 1 hour and 6 minutes, making it an ideal candidate for a simple day trip that requires no overnight stay. You should budget approximately $8 for fuel to cover the distance comfortably. Because the route stays entirely within the state, you won't experience significant regional transitions, ensuring a consistent driving experience. It is a practical, no-nonsense connection between these two points, perfect for travelers prioritizing efficiency over complex sightseeing. Whether you are heading north for business or a quick visit, this route offers a reliable and predictable path.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

0 planned breaks

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

26.1 miles from Waynesboro, MS

A natural place for your longest stop of the day , about 32m into the drive .

Drive Character

Expect a highway-focused experience, as 92% of this route consists of high-speed transit. You will spend the bulk of your time on US 45, which accounts for a 43.2-mile stretch of the journey, providing a steady pace behind the wheel. The road transitions from this primary artery into MS 145 and Mississippi Drive as you approach your final destination. Because it is largely a highway drive, the character is functional rather than technical, favoring consistent speed over winding, scenic detours. You can anticipate a smooth, uninterrupted flow that allows you to cover the distance without the fatigue associated with navigating complex local road networks.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 19 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 45 is the longest continuous segment at about 43.2 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US 45 and MS 145. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.3 miles in near MS 145 / Mississippi Drive.

Route Complexity 4/10

Easy - simple navigation with a manageable amount of wheel time

This is a straightforward 1h 6m drive. You will face about 6 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: at 0.3 miles (MS 145 / Mississippi Drive): Navigation decision point; at 3.6 miles (US 45): Lane positioning matters here; at 46.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Critical Maneuvers

5 of 6 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

4
0.3 mi into trip | ~0m in | MS 145 / Mississippi Drive

Turn left onto MS 145 / Mississippi Drive

Navigation decision point

5
3.6 mi into trip | ~6m in | US 45

At end of road, turn left onto US 45

Lane positioning matters here

Use the straight lane.
6
46.8 mi into trip | ~56m in

Take the exit toward MS 145: Meridian

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Toward MS 145: Meridian
6
47.2 mi into trip | ~57m in | MS 145

At end of road, turn left onto MS 145

Lane positioning matters here

Use the straight lane.
5
52.1 mi into trip | ~1h 6m in | 25th Avenue

Turn left onto 25th Avenue

Navigation decision point

Main Roads

Road Distance Duration
US 45 43.2 mi 50m
MS 145 4.8 mi 8m
Mississippi Drive 3.4 mi 5m
Azalea Drive 0.3 mi <1m
8th Street 0.2 mi <1m
25th Avenue <0.1 mi <1m
Longest stretch: US 45 — 43.2 mi, about 50m

Turn-by-Turn Driving Directions

Step-by-step road directions between Waynesboro, MS and Meridian, MS.

1

Start on MS 184

0.3 mi · 33 sec · Azalea Drive
2

Turn left onto MS 145

3.4 mi · 5 min · Mississippi Drive
3

At end of road, turn left onto US 45

2.0 mi · 2 min · US 45
Use the straight lane.
4

Continue on US 45

0.7 mi · 49 sec · US 45
Use the straight lane.
5

Continue on US 45

1.7 mi · 1 min · US 45
Use the straight lane.
6

Continue on US 45

1.8 mi · 2 min · US 45
Use the straight lane.
7

Continue on US 45

6.3 mi · 7 min · US 45
Use the straight lane.
8

Continue on US 45

5.6 mi · 6 min · US 45
Use the straight lane.
9

Continue on US 45

3.5 mi · 4 min · US 45
Use the straight lane.
10

Continue on US 45

4.7 mi · 5 min · US 45
Use the straight lane.
11

Continue on US 45

5.3 mi · 6 min · US 45
Use the straight lane.
12

Continue on US 45

3.7 mi · 4 min · US 45
Use the straight lane.
13

Continue on US 45

1.3 mi · 1 min · US 45
Use the straight lane.
14

Continue on US 45

6.4 mi · 7 min · US 45
Use the straight lane.
15

Take the exit

0.3 mi · 51 sec
Toward MS 145: Meridian Use the straight / slight right lanes.
16

At end of road, turn left onto MS 145

4.8 mi · 8 min · MS 145
Use the straight lane.
17

Turn left onto 8th Street

0.2 mi · 25 sec · 8th Street
18

Turn left onto 25th Avenue

272 ft · 11 sec · 25th Avenue
19

Arrive at destination

25th Avenue

Trip Plan

Since this is a short trip, you have plenty of flexibility to plan your departure around your personal schedule. With no mandatory stops required to complete the 52.2-mile distance, you can easily drive the entire segment in one go. Keep in mind that the majority of your time is spent on US 45, so stay alert for changing speed limits as you transition onto MS 145 and Mississippi Drive near Meridian. It is helpful to fuel up before leaving Waynesboro to take advantage of your $8 budget estimate and avoid unnecessary stops. By maintaining a steady pace on the highway, you can reach your destination in just over an hour without needing to break up the drive.

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 26.1 miles from Waynesboro, MS, or about 32m into the drive.
The longest continuous stretch on this route runs about 43.2 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 52.2 miles or 1h 6m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 26.1 miles or 32m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 53m

Traffic, exits, and arrival timing usually matter more near Meridian, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Waynesboro, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Waynesboro, MS

This is one driving day of about 52.2 miles and 1h 6m.

Your first comfortable stop window is around 80 miles from Waynesboro, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
You may only need one short stretch stop if conditions stay smooth.
The longest stretch is on US 45 for about 43.2 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 26.1 mi from Waynesboro, MS · 32m into the drive

Downtown Butler, AL, AL

Mid-route town

Meal stop

Butler, AL

26 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Butler, AL

Fuel and coffee

A short stop after about 52.2 miles helps settle the day before fatigue starts building.

Butler, AL

Meal break

The midpoint is around 26.1 miles from Waynesboro, MS, which is a good place for a longer meal and fuel stop.

Arriving in Meridian, MS

The final approach into Meridian, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Meridian, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$7.98 one way

$15.96 round trip

$3.88/gal 25.4 MPG avg 18 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.26 $8.75 $17.51
premium $4.61 $9.47 $18.95
diesel $5.64 $11.60 $23.19

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$8

Meals

$25–$50

Total

$33–$58

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 18.3 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $5 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 15.7 0 $5.48 $2.51
Efficient EV 13.1 0 $4.57 $2.09
EV Truck/SUV 20.9 0 $7.31 $3.34

Gas CO2

18 kg

EV CO2

6 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Local time and weather at both ends of the drive

Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.

Forecast data refreshed 2 days ago

Origin

Waynesboro, MS

Late night in Waynesboro on Sunday

Local time

3:57 AM

CDT

Current temp

63°F

Forecast unavailable right now

CDT Live forecast

Destination

Meridian, MS

Late night in Meridian on Sunday

Local time

3:57 AM

CDT

Current temp

63°F

Forecast unavailable right now

CDT Live forecast

Along the Route

86°F

Butler, AL

26 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

Very similar conditions

Both ends of the route are sitting at about the same temperature right now.

Road read

1h 6m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Frequently Asked Questions

The drive from Waynesboro, MS to Meridian, MS covers 52.2 miles and takes about 1h 6m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 45, MS 145, Mississippi Drive. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 26.1 miles from Waynesboro, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $7.98 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a straightforward 1h 6m drive. You will face about 6 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: at 0.3 miles (MS 145 / Mississippi Drive): Navigation decision point; at 3.6 miles (US 45): Lane positioning matters here; at 46.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
The route from Waynesboro, MS to Meridian, MS does not surface many named destination signs beyond the main corridor.

Was this route helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Explore more options from Waynesboro, MS or browse trips ending in Meridian, MS.

Looking for more statewide routes? Browse MS road trips.

Explore maps for Waynesboro, MS or Meridian, MS on MapSof.net.