Trip from Anna, TX to San Antonio, TX

Drive Time

5h 44m

Distance

316.9 mi

510 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$48

one way

Downtown San Antonio, TX, TX

Photo: Wikimedia Commons

Trip Overview

Traveling from Anna to San Antonio covers 340.9 miles and typically takes about 5 hours and 3 minutes of driving time. Because this route stays entirely within the Great Plains region of Texas, you will experience consistent terrain throughout your journey. With a recommended duration of just one day, it is perfectly feasible to complete this trip in a single session. Budgeting approximately $51 for fuel should cover your needs, provided you stick to the planned itinerary. Since you will be navigating via local roads like West 4th Street, South Powell Parkway, and McKinney Street, expect a more hands-on driving experience rather than a simple highway cruise. This route is ideal if you prefer local roads over high-speed interstates.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

158.4 miles from Anna, TX

A natural place for your longest stop of the day , about 2h 52m into the drive .

Drive Character

Expect a turn-heavy local drive that demands your full attention behind the wheel. Unlike a standard interstate trek, this journey features a 0% highway share, meaning you will spend the entire 340.9 miles navigating surface streets and local thoroughfares. There is no "longest stretch" of uninterrupted highway here, as the route is defined by consistent turns on roads like West 4th Street. You will feel the technical nature of the drive as you transition through various local intersections rather than settling into a cruise-control rhythm. Be prepared for a more engaged, manual driving experience that keeps you focused on the road ahead for the duration of the 5-hour trip.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 40 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Purple Heart Trail is the longest continuous segment at about 99.6 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on Purple Heart Trail and South R L Thornton Freeway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 6.8 miles in.

Route Complexity 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 28 significant decision points across 316.9 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 6.8 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 42.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 44.7 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 28 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

8
6.8 mi into trip | ~10m in

Keep slight left at fork toward US 75 South, TX 121 South

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 75 South, TX 121 South
8
42.6 mi into trip | ~49m in

Take the exit toward Downtown, Good-Latimer Expressway

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Exit 284C Toward Downtown, Good-Latimer Expressway
9
44.7 mi into trip | ~53m in

Keep slight left at fork toward I 35E North, I 35E South: Denton, Waco

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward I 35E North, I 35E South: Denton, Waco
8
235.3 mi into trip | ~4h 12m in | I 35; US 290 / Purple Heart Trail

Keep slight left at fork onto I 35; US 290 / Purple Heart Trail toward 32nd Street, Dean Keeton Street

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Toward 32nd Street, Dean Keeton Street
8
315.1 mi into trip | ~5h 41m in | I 35 / North Pan Am Expressway

Keep slight left at fork onto I 35 / North Pan Am Expressway toward I 35 South: Lower Level, Laredo

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Toward I 35 South: Lower Level, Laredo

Towns Along This Route

Between Anna, TX and San Antonio, TX, road signs point toward Downtown, Denton, Waco and Dallas Zoo.

Downtown

42.6 mi in | ~49m

Denton

44.5 mi in | ~53m

Waco

44.7 mi in | ~53m

Dallas Zoo

45.6 mi in | ~55m | via I 35E

Main Roads

Road Distance Duration
Purple Heart Trail 99.6 mi 1h 46m
South R L Thornton Freeway 89.9 mi 1h 32m
I 35 55.8 mi 58m
Central Expressway 35 mi 37m
North Pan Am Expressway 17 mi 20m
North Jack Kultgen Expressway 6.6 mi 7m
McKinney Street 3.3 mi 5m
South Powell Parkway 2.4 mi 3m
Longest stretch: Purple Heart Trail — 99.6 mi, about 1h 46m

Turn-by-Turn Driving Directions

Step-by-step road directions between Anna, TX and San Antonio, TX.

1

Start on South Sherley Road

35 ft · 8 sec · South Sherley Road
2

Turn left onto FM 2862

0.2 mi · 23 sec · West 4th Street
3

Turn left onto TX 5

2.4 mi · 3 min · South Powell Parkway
4

Continue on TX 5

3.3 mi · 5 min · McKinney Street
5

Turn right onto TX 121

1.0 mi · 1 min · Sam Rayburn Highway
6

Keep slight left at fork

0.8 mi · 1 min
Toward US 75 South, TX 121 South Use the straight / slight right lanes.
7

Merge onto US 75; TX 121

35 mi · 37 min · Central Expressway
Use the straight / slight right lanes.
8

Take the exit

501 ft · 12 sec
Exit 284C Toward Downtown, Good-Latimer Expressway Use the slight left lane.
9

Continue on North Central Expressway

0.7 mi · 1 min · North Central Expressway
Use the left / straight lanes.
10

Turn right onto Elm Street

304 ft · 10 sec · Elm Street
11

Turn left onto North Pearl Expressway

0.2 mi · 28 sec · North Pearl Expressway
Use the straight lane.
12

Turn right onto Young Street

0.1 mi · 19 sec · Young Street
13

Turn left onto South Harwood Street

315 ft · 8 sec · South Harwood Street
Use the left lane.
14

Turn right onto Canton Street

0.4 mi · 47 sec · Canton Street
15

Take the ramp

0.3 mi · 38 sec
Toward I 30 West
16

Keep slight left at fork

0.1 mi · 14 sec
Toward I 35E South, I 35E North: Waco, Denton
17

Keep slight left at fork

221 ft · 5 sec
Toward I 35E North, I 35E South: Denton, Waco Use the straight / slight right lanes.
18

Keep slight left at fork

0.4 mi · 30 sec
Toward I 35E South: Waco Use the left / right lanes.
19

Continue on I 35E

0.5 mi · 44 sec · South R L Thornton Freeway
20

Continue on I 35E

89 mi · 1 hr 31 min · South R L Thornton Freeway
Exit 426 Toward Dallas Zoo Use the straight / slight right lanes.
21

Continue on I 35; US 77

6.6 mi · 7 min · North Jack Kultgen Expressway
Use the straight / slight right lanes.
22

Continue on I 35

38 mi · 39 min · Purple Heart Trail
Use the straight / slight right lanes.
23

Keep slight left at fork onto I 35

56 mi · 58 min · I 35
Use the straight / slight right lanes.
24

Keep slight left at fork onto I 35; US 290

50 mi · 54 min · Purple Heart Trail
Toward 32nd Street, Dean Keeton Street Use the slight left lane.
25

Continue on I 35

1.7 mi · 1 min · Interstate Highway 35
Use the straight / slight right lanes.
26

Continue on I 35

12 mi · 12 min · Purple Heart Trail
Use the straight / slight right lanes.
27

Continue on I 35

10.0 mi · 11 min · North Pan Am Expressway
Use the straight / slight right lanes.
28

Keep slight left at fork onto I 35

6.4 mi · 8 min · North Pan Am Expressway
Toward I 35 South Use the straight / slight right lanes.
29

Keep slight left at fork onto I 35

0.6 mi · 41 sec · North Pan Am Expressway
Toward I 35 South: Lower Level, Laredo Use the slight left lane.
30

Take the exit

0.1 mi · 16 sec
Exit 157A Toward Lexington Avenue, Main Avenue, San Pedro Avenue Use the slight right lane.
31

Turn straight onto East Elmira Street

526 ft · 17 sec · East Elmira Street
Use the left / straight lanes.
32

Turn left onto North Main Avenue

0.2 mi · 18 sec · North Main Avenue
Use the left / straight lanes.
33

Enter roundabout onto Navarro Street

159 ft · 3 sec · Navarro Street
34

Continue on Navarro Street

111 ft · 2 sec · Navarro Street
35

Keep slight right at fork onto North Main Avenue

0.4 mi · 51 sec · North Main Avenue
Use the slight left / slight right lanes.
36

Turn right onto West Travis Street

222 ft · 10 sec · West Travis Street
37

Turn left onto North Flores Street

0.2 mi · 20 sec · North Flores Street
38

Continue on Military Plaza

392 ft · 15 sec · Military Plaza
39

Turn left onto Dolorosa Street

327 ft · 8 sec · Dolorosa Street
40

Arrive at destination

Dolorosa Street

Trip Plan

To keep your 5-hour and 3-minute drive manageable, plan for at least one dedicated stop to break up the frequent turns. Departing early in the day is your best bet to avoid the buildup of local traffic on these specific surface streets. Since the route relies on local roads rather than major highways, keep a close eye on your navigation system to ensure you don't miss any of the frequent turns. With a fuel budget of $51, it is wise to fill up before you leave Anna to avoid hunting for gas stations during the more technical portions of the drive. The flexibility of a one-day trip allows you to adjust your pace as needed, so prioritize comfort and regular breaks to stay alert.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 158.4 miles from Anna, TX, or about 2h 52m into the drive.
The longest continuous stretch on this route runs about 99.6 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 30m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 158.4 miles or 2h 52m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 39m

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Anna, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Anna, TX

This is one driving day of about 316.9 miles and 5h 44m.

Your first comfortable stop window is around 80 miles from Anna, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Purple Heart Trail for about 99.6 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 158.4 mi from Anna, TX · 2h 52m into the drive

Downtown Killeen, TX, TX

Mid-route town

Meal stop

Killeen, TX

158 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Grand Prairie, TX

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Killeen, TX

Meal break

The midpoint is around 158.4 miles from Anna, TX, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Purple Heart Trail if your tank is already low. That segment runs about 99.6 miles.

Arriving in San Antonio, TX

The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$48.41 one way

$96.82 round trip

$3.88/gal 25.4 MPG avg 111 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $53.05 $106.10
premium $4.59 $57.28 $114.56
diesel $5.64 $70.40 $140.81

Estimated Tolls: $2.86

Central Expressway (35.7 mi) $2.86

Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.

Estimated Trip Cost (one way, 1 person)

Fuel

$48

Tolls

$3

Meals

$25–$50

Total

$76–$101

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 110.9 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $33 in charging · 1 stop · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 95.1 1 $33.27 $15.21
Efficient EV 79.2 0 $27.73 $12.68
EV Truck/SUV 126.8 1 $44.37 $20.28

Gas CO2

111 kg

EV CO2

37 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 2 days ago

Origin

Anna, TX

Afternoon in Anna on Sunday

Local time

1:35 PM

CDT

Current temp

58°F

Unavailable

Live forecast

Destination

San Antonio, TX

Afternoon in San Antonio on Sunday

Local time

1:35 PM

CDT

Current temp

81°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

23 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 44m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Anna, TX to San Antonio, TX covers 316.9 miles and takes about 5h 44m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Purple Heart Trail, South R L Thornton Freeway, I 35. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 158.4 miles from Anna, TX. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $48.41 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 28 significant decision points across 316.9 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 6.8 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 42.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 44.7 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Anna, TX and San Antonio, TX, road signs point toward Downtown, Denton, Waco and Dallas Zoo.

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