This 135.8-mile journey from Biloxi, MS to Monticello, MS is a straightforward drive that can easily be completed in a single day, taking approximately 2 hours and 50 minutes. With 97% of the route on highways, it's a focused drive primarily utilizing US 49 and US 84, with a portion on MS 15. You can expect a fuel cost of around $21 for this trip. Given its manageable length and highway-focused profile, this route is ideal for a day trip, allowing for flexibility in your schedule. The drive remains within the Southeast region, offering a consistent experience throughout.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
67.9 miles from Biloxi, MS
A natural place for your longest stop of the day
, about 1h 22m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 50m. Total distance: 135.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 50m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (97%). Some complex stretches to watch for.
Drive Character
Expect a predominantly highway-focused drive for this 135.8-mile trip, with 97% of your journey taking place on high-speed roads. The longest uninterrupted stretch you'll encounter is 74.6 miles on US 49, so plan for extended periods of consistent driving. While the route is primarily highway, the transition between US 49, US 84, and MS 15 will offer slight variations in the road's character. This is a drive where you'll likely maintain a steady pace for much of the 2-hour and 50-minute duration.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 23 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 49 is the longest continuous segment at about 74.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US 49 and US 84. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 1 miles in near Bohn Street.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 135.8 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 1 miles (Bohn Street): Navigation decision point; at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.
Critical Maneuvers
5 of 11 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
4
1 mi into trip|~3m in|Bohn Street
Take the ramp onto Bohn Street
Navigation decision point
6
25.1 mi into trip|~32m in
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 49 North: Hattiesburg, Jackson
5
25.5 mi into trip|~33m in|US 49
Merge onto US 49
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
4
100.1 mi into trip|~2h 5m in
Take the exit toward MS 184: Downtown Collins
Exit ramp - move to the correct lane early
Toward MS 184: Downtown Collins
4
100.4 mi into trip|~2h 6m in
Turn left
Navigation decision point
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Biloxi, MS to Monticello, MS, road signs begin pointing toward Jackson along the way.
Jackson
25.1 mi in|~32m
Main Roads
Road
Distance
Duration
US 49
74.6 mi
1h 32m
US 84
30 mi
34m
MS 15
20.7 mi
24m
MS 184
3.7 mi
6m
I 110
3.1 mi
4m
Main Street
2.2 mi
4m
Division Street
0.5 mi
1m
Bohn Street
<0.1 mi
<1m
Longest stretch:
US 49
— 74.6 mi, about 1h 32m
Turn-by-Turn Driving Directions
Step-by-step road directions between Biloxi, MS and Monticello, MS.
1
Start on Howard Avenue
91 ft·6 sec·Howard Avenue
2
Turn right onto Main Street
0.5 mi·1 min·Main Street
3
Turn left onto Division Street
0.5 mi·1 min·Division Street
4
Take the ramp onto Bohn Street
139 ft·3 sec·Bohn Street
5
Turn straight
0.3 mi·37 sec
6
Merge onto I 110
3.1 mi·4 min·I 110
7
Continue on MS 15; MS 67
21 mi·24 min·MS 15; MS 67
Use the straight lane.
8
Keep slight right at fork
0.4 mi·47 sec
Toward US 49 North: Hattiesburg, Jackson
9
Merge onto US 49
40 mi·46 min·US 49
Use the straight lane.
10
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
11
Turn straight onto US 49
10 mi·16 min·US 49
Use the straight lane.
12
Continue on US 49; MS 42
5.4 mi·6 min·US 49; MS 42
Use the straight lane.
13
Continue on US 49
5.3 mi·6 min·US 49
Use the straight lane.
14
Continue on US 49
0.2 mi·14 sec·US 49
Use the straight lane.
15
Continue on US 49
4.2 mi·4 min·US 49
Use the straight lane.
16
Continue on US 49
7.1 mi·8 min·US 49
Use the straight lane.
17
Take the exit
0.2 mi·36 sec
Toward MS 184: Downtown Collins
18
Turn left
72 ft·2 sec
19
Turn left onto MS 184
1.8 mi·2 min·Main Street
20
Turn left onto US 84
10 mi·12 min·US 84
21
Continue on US 84
20 mi·22 min·US 84
22
Turn left onto MS 184
3.7 mi·6 min·MS 184
23
Arrive at destination
MS 184
Trip Plan
For this 135.8-mile drive, leaving in the morning is recommended to maximize daylight and allow for potential impromptu stops. With a duration of under 3 hours and a fuel cost of approximately $21, this route offers considerable flexibility. You'll spend most of your time on US 49, US 84, and MS 15, so keep an eye on your fuel gauge, especially during the longest 74.6-mile stretch on US 49. While a single stop is likely sufficient, consider a brief break midway to stretch your legs and stay refreshed.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 67.9 miles from Biloxi, MS, or about 1h 22m into the drive.
The longest continuous stretch on this route runs about 74.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 30 miles or 38m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 67.9 miles or 1h 22m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 19m
Traffic, exits, and arrival timing usually matter more near Monticello, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Biloxi, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Biloxi, MS
This is one driving day of about 135.8 miles and 2h 50m.
Your first comfortable stop window is around 30 miles from Biloxi, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49 for about 74.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 67.9 mi from Biloxi, MS
· 1h 22m into the drive
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$20.51 one way
$41.02 round trip
$3.84/gal25.4 MPG avg48 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$22.51
$45.03
premium
$4.56
$24.37
$48.75
diesel
$5.61
$29.98
$59.97
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$21
Meals
$25–$50
Total
$46–$71
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 47.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $14 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
40.7
0
$14.26
$6.52
Efficient EV
34
0
$11.88
$5.43
EV Truck/SUV
54.3
0
$19.01
$8.69
Gas CO2
48 kg
EV CO2
16 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Biloxi, MS
Morning
in Biloxi on Friday
Local time
10:51 AM
CDT
Current temp
61°F
Unavailable
Live forecast
Destination
Monticello, MS
Morning
in Monticello on Friday
Local time
10:51 AM
CDT
Current temp
79°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
18 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 50m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Biloxi, MS to Monticello, MS covers 135.8 miles and takes about 2h 50m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 49, US 84, MS 15. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 67.9 miles from Biloxi, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $20.51 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This drive requires moderate attention. Across 135.8 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: at 1 miles (Bohn Street): Navigation decision point; at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.
On the drive from Biloxi, MS to Monticello, MS, road signs begin pointing toward Jackson along the way.
