Origin
De Soto, MO
Afternoon in De Soto on Sunday
Local time
2:28 PM
CDT
Current temp
53°F
Unavailable
Live forecast
Trip from De Soto, MO to East Independence, MO
Drive Time
4h 16m
Distance
264.9 mi
426 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$40
one way
De Soto, MO
Tien Nguyen
East Independence, MO
Ankit Rainloure
Trip Overview
The drive from De Soto, MO to East Independence, MO covers 264.9 miles and takes about 4h 16m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on North Main Street, MO 21 North, MO 141 for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $40.24 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
132.5 miles from De Soto, MO
A natural place for your longest stop of the day , about 2h 8m into the drive .
Drive Character
Expect a 4h 16m drive with frequent turns across 264.9 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 29 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
North Main Street is one of the defining roads on this drive.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Route Complexity
3/10
Easy - simple navigation with a manageable amount of wheel time
This is a straightforward 4h 16m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from De Soto, MO to East Independence, MO is straightforward, with well-signed roads and simple exits.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| North Main Street | Unavailable | Refreshing |
| MO 21 North | Unavailable | Refreshing |
| MO 141 | Unavailable | Refreshing |
| I 64 West | Unavailable | Refreshing |
| Avenue of the Saints | Unavailable | Refreshing |
| I 70 West | Unavailable | Refreshing |
| Dwight D Eisenhower Highway | Unavailable | Refreshing |
| Sheriff Roger I | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Longest stretch:
North Main Street
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between De Soto, MO and East Independence, MO.
1
Start on Easton Street
436 ft
·
24 sec
·
Easton Street
2
At the end of the road, turn left onto North Main Street
1.4 mi
·
2 min
·
North Main Street
3
At the end of the road, turn left
1.5 mi
·
1 min
4
At the end of the road, turn right
407 ft
·
6 sec
5
Continue straight
3.8 mi
·
5 min
6
Turn left
0.4 mi
·
36 sec
7
Continue on MO 21 North: Saint Louis
20 mi
·
22 min
·
MO 21 North: Saint Louis
8
Take the exit slight right toward MO 141: Arnold, Fenton
0.3 mi
·
24 sec
·
MO 141: Arnold, Fenton
9
Turn left
4.0 mi
·
5 min
10
Keep slight left to continue on MO 141
11 mi
·
17 min
·
MO 141
11
Take the exit slight left toward I 64 West, US 40 West, US 61 North: Wentzville
135 ft
·
7 sec
·
I 64 West, US 40 West, US 61 North: Wentzville
12
Turn left onto I 64 West, US 40 West, US 61 North: Wentzville
0.3 mi
·
44 sec
·
I 64 West, US 40 West, US 61 North: Wentzville
13
Merge slight left onto Avenue of the Saints
22 mi
·
26 min
·
Avenue of the Saints
14
Take the exit slight left toward I 70 West, US 40 West: Kansas City
0.6 mi
·
1 min
·
I 70 West, US 40 West: Kansas City
15
Merge slight left onto Dwight D Eisenhower Highway
81 mi
·
1 hr 35 min
·
Dwight D Eisenhower Highway
16
Continue on Sheriff Roger I. Wilson Memorial Highway
2.0 mi
·
2 min
·
Sheriff Roger I. Wilson Memorial Highway
17
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi
·
1 min
·
Highway Patrol Sgt. Benjamin Booth Memorial Highway
18
Continue on Dwight D. Eisenhower Highway
1.8 mi
·
2 min
·
Dwight D. Eisenhower Highway
19
Continue on U.S. Submarine Veterans' Memorial Highway
54 mi
·
58 min
·
U.S. Submarine Veterans' Memorial Highway
20
Continue on Dwight D. Eisenhower Highway
52 mi
·
56 min
·
Dwight D. Eisenhower Highway
21
Take the exit slight right toward Little Blue Parkway, 39th Street, Mall Entrance
0.3 mi
·
40 sec
·
Little Blue Parkway, 39th Street, Mall Entrance
22
Turn right onto South Little Blue Parkway
1.6 mi
·
3 min
·
South Little Blue Parkway
23
Turn left onto East R.D. Mize Road
0.2 mi
·
38 sec
·
East R.D. Mize Road
24
Turn right onto South Jackson Drive
1.2 mi
·
2 min
·
South Jackson Drive
25
Turn straight onto Holke Road
0.9 mi
·
2 min
·
Holke Road
26
Turn left onto East Truman Road
0.7 mi
·
1 min
·
East Truman Road
27
Turn right onto Main Road
0.3 mi
·
1 min
·
Main Road
28
Turn right onto East 9th Street South
79 ft
·
3 sec
·
East 9th Street South
29
Arrive at your destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 132.5 miles from De Soto, MO, or about 2h 8m into the drive.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 17m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 132.5 miles or 2h 8m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 30m
Traffic, exits, and arrival timing usually matter more near East Independence, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving De Soto, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from De Soto, MO
This is one driving day of about 264.9 miles and 4h 16m.
Your first comfortable stop window is around 80 miles from De Soto, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 132.5 mi from De Soto, MO · 2h 8m into the drive
Mid-route town
Meal stop
132 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 80 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 132.5 miles from De Soto, MO, which is a good place for a longer meal and fuel stop.
Arriving in East Independence, MO
The final approach into East Independence, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around East Independence, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$40.24 one way
$80.47 round trip
$3.86/gal
25.4 MPG avg
93 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $44.36 | $88.71 |
| premium | $4.80 | $50.01 | $100.02 |
| diesel | $5.64 | $58.85 | $117.70 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$40
Meals
$25–$50
Total
$65–$90
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 92.7 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $28 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 79.5 | 0 | $27.81 | $12.72 |
| Efficient EV | 66.2 | 0 | $23.18 | $10.60 |
| EV Truck/SUV | 106 | 1 | $37.09 | $16.95 |
Gas CO2
93 kg
EV CO2
31 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
East Independence, MO
Afternoon in East Independence on Sunday
Local time
2:28 PM
CDT
Current temp
49°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
4 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 16m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from De Soto, MO to East Independence, MO covers 264.9 miles and takes about 4h 16m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are North Main Street, MO 21 North, MO 141. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 132.5 miles from De Soto, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $40.24 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a straightforward 4h 16m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
This route does not have any notably tricky sections. Most of the drive from De Soto, MO to East Independence, MO is straightforward, with well-signed roads and simple exits.
The route from De Soto, MO to East Independence, MO does not surface many named destination signs beyond the main corridor.
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