Origin
Hereford, TX
Afternoon in Hereford on Sunday
Local time
1:33 PM
CDT
Current temp
43°F
Unavailable
Drive Time
8h 42m
Distance
485.7 mi
782 km
Drive Score
8/10
Great drive
Same Day?
2-day trip
Fuel Cost
$74
one way
Photo: Wikimedia Commons
Traveling from Hereford to San Antonio covers 496.7 miles across the Texas Great Plains. You should plan for a driving time of approximately 7 hours and 34 minutes, making this a long but manageable single-day commitment for most drivers. Because the route relies on local roads like West 1st Street, South 25 Mile Avenue, and North Main Street rather than high-speed interstates, it demands your full attention behind the wheel. Expect to budget roughly $74 for fuel to complete the journey. While it is possible to finish the trip in one day, the turn-heavy nature of the drive makes it a significant undertaking that requires careful pacing.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
242.8 miles from Hereford, TX
A natural place for your longest stop of the day , about 4h 25m into the drive .
This journey is defined by its turn-heavy local road profile, offering a much different experience than a standard interstate cruise. With a 0% highway share, you will be navigating local arteries for the entire 496.7-mile duration. The route requires consistent engagement, as you transition between local streets rather than maintaining a steady pace on a controlled-access road. You should be prepared for a slower, more deliberate driving pace compared to major highways. Staying alert is essential, as the lack of highway stretches means you will encounter frequent shifts in road geometry as you move through the Great Plains.
This is a straightforward highway drive that stays mostly on US Highway 84 and I 10. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 64.2 miles in near US 385; Loop 430 / East Delano Avenue.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 23 significant decision points across 485.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 64.2 miles (US 385; Loop 430 / East Delano Avenue): Lane positioning matters here; at 66.5 miles (US 84): Lane positioning matters here; at 216.9 miles (US 84): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
At end of road, turn left onto US 385; Loop 430 / East Delano Avenue
Lane positioning matters here
Turn left onto US 84
Lane positioning matters here
Keep slight left at fork onto US 84 toward I 20 East, US 84 East: Abilene
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit onto US 83 toward I 10 East: San Antonio
Exit ramp - move to the correct lane early. Lane positioning matters here
Take the exit toward Santa Rosa Street, Downtown
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Between Hereford, TX and San Antonio, TX, road signs point toward Sh 70 South, Sh 70 Business: Sweetwater and San Angelo.
Sh 70 South
Sh 70 Business: Sweetwater
San Angelo
| Road | Distance | Duration |
|---|---|---|
| US Highway 84 | 73.9 mi | 1h 14m |
| I 10 | 71.7 mi | 1h 14m |
| US 385 | 42.4 mi | 44m |
| Grassmeyer Street | 41.9 mi | 44m |
| US 84 | 40 mi | 42m |
| US 83 | 40 mi | 38m |
| State Highway 153 | 29.5 mi | 33m |
| Ellis Street | 29.4 mi | 31m |
Step-by-step road directions between Hereford, TX and San Antonio, TX.
Start on this road
Turn right onto US 60
Turn left onto US 385
Turn right onto US 385
Turn straight onto North Main Street
Continue on US 385
Turn straight onto US 385
At end of road, turn left onto US 385; Loop 430
Turn left onto US 84
Merge onto US 84
Continue on US 84
Continue on US 84
Continue on US 84
Continue on US 84
Continue on US 84
Turn left onto Spur 575
Turn right onto TX 207
Turn straight onto TX 207
At end of road, turn left onto US 84
Keep slight left at fork onto US 84
Take the exit
Turn slight left onto Southwest Georgia Avenue
Turn right onto TX 70
Continue on TX 70
Turn left onto TX 153
Turn right onto FM 2111
Turn left onto TX 158
At end of road, turn right onto US 67; US 83
Turn left onto US 83
Continue on US 83
Continue on US 83
Take the exit onto US 83
Continue on I 10
Keep slight right at fork onto I 10; US 87
Keep slight right at fork onto I 10; US 87
Take the exit
Turn straight onto North Pecos-La Trinidad
Keep slight right at fork onto North Pecos-La Trinidad
Turn left onto Dolorosa Street
Arrive at destination
Given the 7 hour and 34 minute duration, departing early in the morning is your best strategy to avoid fatigue during the final leg of the trip. Plan for at least two stops along the way to stretch your legs and break up the repetitive nature of local road navigation. Since this route utilizes city-focused streets like North Main Street, keep a close watch on local traffic patterns and changing speed limits. Budgeting $74 for fuel is a solid baseline, but keep a little extra set aside for potential fluctuations depending on your vehicle's efficiency. Because the route is entirely local, use your navigation tools proactively to manage the numerous turns required to reach San Antonio.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 107 miles or 2h 4m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 242.8 miles or 4h 25m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 242.8 miles or 4h 25m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 7h 37m
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Open the route before leaving Hereford, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from Hereford, TX
Aim for roughly 243 miles and 4.4 hours of wheel time on this day.
Day 2
Finish the approach into San Antonio, TX
Aim for roughly 243 miles and 4.4 hours of wheel time on this day.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 242.8 mi from Hereford, TX · 4h 25m into the drive
Mid-route town
Overnight candidate
243 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Find hotels in Sweetwater, TXNight 1
243 mi · about 4.4h in
A practical overnight split lands near Sweetwater, TX after about 243 miles or 4.4 hours of driving.
Find hotelsA short stop after about 107 miles helps settle the day before fatigue starts building.
The midpoint is around 242.8 miles from Hereford, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US Highway 84 if your tank is already low. That segment runs about 73.9 miles.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 243 miles or 4.4 hours on the road.
The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.
On a multi-day trip, keep the last day a little lighter so you reach San Antonio, TX with some flexibility left in the schedule.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$74.19 one way
$148.39 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $81.31 | $162.61 |
| premium | $4.59 | $87.79 | $175.58 |
| diesel | $5.64 | $107.91 | $215.81 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$74
Hotel (1n)
$80–$140
Meals
$50–$100
Total
$204–$314
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 169.9 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $51 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 145.7 | 1 | $51.00 | $23.31 |
| Efficient EV | 121.4 | 1 | $42.50 | $19.43 |
| EV Truck/SUV | 194.3 | 2 | $68.00 | $31.08 |
Gas CO2
170 kg
EV CO2
57 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Hereford on Sunday
Local time
1:33 PM
CDT
Current temp
43°F
Unavailable
Destination
Afternoon in San Antonio on Sunday
Local time
1:33 PM
CDT
Current temp
81°F
Unavailable
Along the Route
55°F
Sweetwater, TX
243 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Hereford, TX or browse trips ending in San Antonio, TX.
Looking for more statewide routes? Browse TX road trips.
Explore maps for Hereford, TX or San Antonio, TX on MapSof.net.