Trip from Hereford, TX to San Antonio, TX

Drive Time

8h 42m

Distance

485.7 mi

782 km

Drive Score

8/10

Great drive

Same Day?

2-day trip

Fuel Cost

$74

one way

Downtown San Antonio, TX, TX

Photo: Wikimedia Commons

Trip Overview

Traveling from Hereford to San Antonio covers 496.7 miles across the Texas Great Plains. You should plan for a driving time of approximately 7 hours and 34 minutes, making this a long but manageable single-day commitment for most drivers. Because the route relies on local roads like West 1st Street, South 25 Mile Avenue, and North Main Street rather than high-speed interstates, it demands your full attention behind the wheel. Expect to budget roughly $74 for fuel to complete the journey. While it is possible to finish the trip in one day, the turn-heavy nature of the drive makes it a significant undertaking that requires careful pacing.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

242.8 miles from Hereford, TX

A natural place for your longest stop of the day , about 4h 25m into the drive .

Drive Character

This journey is defined by its turn-heavy local road profile, offering a much different experience than a standard interstate cruise. With a 0% highway share, you will be navigating local arteries for the entire 496.7-mile duration. The route requires consistent engagement, as you transition between local streets rather than maintaining a steady pace on a controlled-access road. You should be prepared for a slower, more deliberate driving pace compared to major highways. Staying alert is essential, as the lack of highway stretches means you will encounter frequent shifts in road geometry as you move through the Great Plains.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 40 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US Highway 84 is the longest continuous segment at about 73.9 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US Highway 84 and I 10. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 64.2 miles in near US 385; Loop 430 / East Delano Avenue.

Route Complexity 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 23 significant decision points across 485.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 64.2 miles (US 385; Loop 430 / East Delano Avenue): Lane positioning matters here; at 66.5 miles (US 84): Lane positioning matters here; at 216.9 miles (US 84): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 23 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

7
64.2 mi into trip | ~1h 17m in | US 385; Loop 430 / East Delano Avenue

At end of road, turn left onto US 385; Loop 430 / East Delano Avenue

Lane positioning matters here

Use the left lane.
6
66.5 mi into trip | ~1h 20m in | US 84

Turn left onto US 84

Lane positioning matters here

Use the none lane.
6
216.9 mi into trip | ~3h 57m in | US 84

Keep slight left at fork onto US 84 toward I 20 East, US 84 East: Abilene

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 20 East, US 84 East: Abilene
8
370.7 mi into trip | ~6h 44m in | US 83

Take the exit onto US 83 toward I 10 East: San Antonio

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the left lane. Toward I 10 East: San Antonio
8
484 mi into trip | ~8h 38m in

Take the exit toward Santa Rosa Street, Downtown

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 569C Toward Santa Rosa Street, Downtown

Towns Along This Route

Between Hereford, TX and San Antonio, TX, road signs point toward Sh 70 South, Sh 70 Business: Sweetwater and San Angelo.

Sh 70 South

223.3 mi in | ~4h 3m

Sh 70 Business: Sweetwater

223.3 mi in | ~4h 3m

San Angelo

223.3 mi in | ~4h 3m

Main Roads

Road Distance Duration
US Highway 84 73.9 mi 1h 14m
I 10 71.7 mi 1h 14m
US 385 42.4 mi 44m
Grassmeyer Street 41.9 mi 44m
US 84 40 mi 42m
US 83 40 mi 38m
State Highway 153 29.5 mi 33m
Ellis Street 29.4 mi 31m
Longest stretch: US Highway 84 — 73.9 mi, about 1h 14m

Turn-by-Turn Driving Directions

Step-by-step road directions between Hereford, TX and San Antonio, TX.

1

Start on this road

242 ft · 19 sec · this road
2

Turn right onto US 60

0.5 mi · 35 sec · West 1st Street
3

Turn left onto US 385

21 mi · 31 min · South 25 Mile Avenue
4

Turn right onto US 385

21 mi · 22 min · US 385
5

Turn straight onto North Main Street

0.1 mi · 11 sec · North Main Street
6

Continue on US 385

5.8 mi · 5 min · US 385
7

Turn straight onto US 385

16 mi · 16 min · US 385
8

At end of road, turn left onto US 385; Loop 430

2.3 mi · 3 min · East Delano Avenue
Use the left lane.
9

Turn left onto US 84

34 mi · 35 min · US 84
Use the none lane.
10

Merge onto US 84

4.0 mi · 4 min · Avenue Q
Use the none lane.
11

Continue on US 84

4.8 mi · 6 min · Slaton Road
12

Continue on US 84

6.9 mi · 6 min · East Highway 84
13

Continue on US 84

4.5 mi · 4 min · Trooper Jerry Don Davis Memorial Highway
14

Continue on US 84

20 mi · 20 min · East Highway 84
Use the none lane.
15

Continue on US 84

1.0 mi · 1 min · North US Highway 84
Use the none lane.
16

Turn left onto Spur 575

0.1 mi · 16 sec · East 15th Street
17

Turn right onto TX 207

0.4 mi · 37 sec · Ralls Road
18

Turn straight onto TX 207

1.1 mi · 2 min · North Avenue F
19

At end of road, turn left onto US 84

74 mi · 1 hr 14 min · US Highway 84
20

Keep slight left at fork onto US 84

6.5 mi · 6 min · US 84
Toward I 20 East, US 84 East: Abilene
21

Take the exit

0.1 mi · 18 sec
Exit 244 Toward SH 70 South, SH 70 Business: Sweetwater, San Angelo
22

Turn slight left onto Southwest Georgia Avenue

0.1 mi · 16 sec · Southwest Georgia Avenue
23

Turn right onto TX 70

0.7 mi · 1 min · Lamar Street
24

Continue on TX 70

10 mi · 10 min · State Highway 70
25

Turn left onto TX 153

29 mi · 33 min · State Highway 153
26

Turn right onto FM 2111

12 mi · 13 min · FM 2111
27

Turn left onto TX 158

6.3 mi · 7 min · TX 158
28

At end of road, turn right onto US 67; US 83

387 ft · 18 sec · Hutchings Avenue
29

Turn left onto US 83

17 mi · 18 min · South 7th Street
Use the left lane.
30

Continue on US 83

42 mi · 44 min · Grassmeyer Street
Use the none lane.
31

Continue on US 83

29 mi · 31 min · Ellis Street
32

Take the exit onto US 83

40 mi · 38 min · US 83
Toward I 10 East: San Antonio Use the left lane.
33

Continue on I 10

54 mi · 54 min · I 10
Use the none / straight / slight right lanes.
34

Keep slight right at fork onto I 10; US 87

17 mi · 19 min · I 10; US 87
Use the none lane.
35

Keep slight right at fork onto I 10; US 87

1.7 mi · 2 min · McDermott Freeway
Use the none lane.
36

Take the exit

0.5 mi · 1 min
Exit 569C Toward Santa Rosa Street, Downtown Use the slight right lane.
37

Turn straight onto North Pecos-La Trinidad

0.2 mi · 16 sec · North Pecos-La Trinidad
38

Keep slight right at fork onto North Pecos-La Trinidad

0.6 mi · 1 min · North Pecos-La Trinidad
Use the straight lane.
39

Turn left onto Dolorosa Street

0.5 mi · 55 sec · Dolorosa Street
Use the straight / left lanes.
40

Arrive at destination

Dolorosa Street

Trip Plan

Given the 7 hour and 34 minute duration, departing early in the morning is your best strategy to avoid fatigue during the final leg of the trip. Plan for at least two stops along the way to stretch your legs and break up the repetitive nature of local road navigation. Since this route utilizes city-focused streets like North Main Street, keep a close watch on local traffic patterns and changing speed limits. Budgeting $74 for fuel is a solid baseline, but keep a little extra set aside for potential fluctuations depending on your vehicle's efficiency. Because the route is entirely local, use your navigation tools proactively to manage the numerous turns required to reach San Antonio.

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 242.8 miles from Hereford, TX, or about 4h 25m into the drive.
The longest continuous stretch on this route runs about 73.9 miles.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 107 miles or 2h 4m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 242.8 miles or 4h 25m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 242.8 miles or 4h 25m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 7h 37m

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Hereford, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

+

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Hereford, TX

Aim for roughly 243 miles and 4.4 hours of wheel time on this day.

Day 2

Finish the approach into San Antonio, TX

Aim for roughly 243 miles and 4.4 hours of wheel time on this day.

Your first comfortable stop window is around 107 miles from Hereford, TX.
This route usually feels better as a 2-day drive than as one long push.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on US Highway 84 for about 73.9 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 242.8 mi from Hereford, TX · 4h 25m into the drive

Downtown Sweetwater, TX, TX

Mid-route town

Overnight candidate

Sweetwater, TX

243 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Sweetwater, TX

Overnight Options

Night 1

Sweetwater, TX

243 mi · about 4.4h in

A practical overnight split lands near Sweetwater, TX after about 243 miles or 4.4 hours of driving.

Find hotels

Pacing Suggestions

Lubbock, TX

Fuel and coffee

A short stop after about 107 miles helps settle the day before fatigue starts building.

Sweetwater, TX

Meal break

The midpoint is around 242.8 miles from Hereford, TX, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before US Highway 84 if your tank is already low. That segment runs about 73.9 miles.

Overnight split

Hotel stop

For a steadier pace, wrap day one after about 243 miles or 4.4 hours on the road.

Arriving in San Antonio, TX

The final approach into San Antonio, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around San Antonio, TX.

On a multi-day trip, keep the last day a little lighter so you reach San Antonio, TX with some flexibility left in the schedule.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$74.19 one way

$148.39 round trip

$3.88/gal 25.4 MPG avg 170 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $81.31 $162.61
premium $4.59 $87.79 $175.58
diesel $5.64 $107.91 $215.81

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$74

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$204–$314

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 169.9 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $51 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 145.7 1 $51.00 $23.31
Efficient EV 121.4 1 $42.50 $19.43
EV Truck/SUV 194.3 2 $68.00 $31.08

Gas CO2

170 kg

EV CO2

57 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 2 days ago

Origin

Hereford, TX

Afternoon in Hereford on Sunday

Local time

1:33 PM

CDT

Current temp

43°F

Unavailable

Live forecast

Destination

San Antonio, TX

Afternoon in San Antonio on Sunday

Local time

1:33 PM

CDT

Current temp

81°F

Unavailable

Live forecast

Along the Route

55°F

Sweetwater, TX

243 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

38 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

8h 42m on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Hereford, TX to San Antonio, TX covers 485.7 miles and takes about 8h 42m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US Highway 84, I 10, US 385. Most of the drive stays on highways, so watch for ramps and exits.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 243 miles on day one.
The midpoint is about 242.8 miles from Hereford, TX. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $74.19 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 23 significant decision points across 485.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 64.2 miles (US 385; Loop 430 / East Delano Avenue): Lane positioning matters here; at 66.5 miles (US 84): Lane positioning matters here; at 216.9 miles (US 84): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Hereford, TX and San Antonio, TX, road signs point toward Sh 70 South, Sh 70 Business: Sweetwater and San Angelo.

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Return Trip

San Antonio, TX to Hereford, TX

Plan the drive back the other way.

485.7 mi 8h 42m

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