The drive from Scott City, MO to Kansas City, MO covers 354.8 miles and takes about 6h 43m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 55, Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway for much of the mileage,
and the overall profile is mixed drive.
The longest uninterrupted segment is about 105.1 miles on I 55.
At current regular gas prices, budget about $55.47 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
177.4 miles from Scott City, MO
A natural place for your longest stop of the day
, about 3h 23m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 43m. Total distance: 354.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 43m drive, plan rest stops for pacing.
Scenic Drive
Mixed drive route profile with national parks nearby.
Drive Character
The drive from Scott City, MO to Kansas City, MO covers 354.8 miles and takes about 6h 43m, using a mix of highways and local roads.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 29 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 55 is the longest continuous segment at about 105.1 miles.
Elevation Profile
Mostly flat terrain
897 ft364 ft
Total Climb
824 ft
Total Descent
290 ft
Highest Point
897 ft
~177.4 mi in
Elevation Range
534 ft
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 107.8 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 15 significant decision points across 354.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 107.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 108.1 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 120.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 15 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
107.8 mi into trip|~1h 57m in
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chi...
8
108.1 mi into trip|~1h 58m in
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left lane.
Toward I 270 West: Kansas City
8
120.4 mi into trip|~2h 14m in
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Lo...
9
354.1 mi into trip|~6h 41m in|I 670; I 70 Alt
Keep slight left at fork onto I 670; I 70 Alt toward I 670 West, I 70 Alternate, I 35 South: Topeka, Wichita
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 2L
Toward I 670 West, I 70 Alternate, I 35 South:...
9
354.3 mi into trip|~6h 41m in
Take the exit toward 13th Street, Downtown
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 2P
Toward 13th Street, Downtown
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Scott City, MO and Kansas City, MO, road signs point toward Chicago and Saint Louis.
Chicago
107.8 mi in|~1h 57m
Saint Louis
120.4 mi in|~2h 14m
Main Roads
Road
Distance
Duration
I 55
105.1 mi
1h 53m
Dwight D Eisenhower Highway
80.7 mi
1h 35m
U.S. Submarine Veterans' Memorial Highway
54.4 mi
58m
Dwight D. Eisenhower Highway
54.3 mi
58m
Avenue of the Saints
25.4 mi
30m
I 270
11.5 mi
14m
George Brett Super Highway
6.8 mi
9m
Truman/Eisenhower Presidential Highway
5.6 mi
6m
Longest stretch:
I 55
— 105.1 mi, about 1h 53m
Turn-by-Turn Driving Directions
Step-by-step road directions between Scott City, MO and Kansas City, MO.
1
Start on MO K
1.0 mi·2 min·Main Street
2
Take the ramp onto US 61 Business
0.4 mi·51 sec·US 61 Business
Toward I 55 North, US 61 North: Cape Girardeau
3
Merge onto I 55; US 61
3.6 mi·3 min·I 55; US 61
4
Keep slight left at fork onto I 55
102 mi·1 hr 49 min·I 55
5
Continue on I 55
1.3 mi·1 min·Rosa Parks Highway
6
Take the exit
0.2 mi·27 sec
Exit 196Toward I 270 West, I 255 East: Kansas City, ChicagoUse the slight right lane.
7
Keep slight left at fork
388 ft·8 sec
Toward I 270 West: Kansas CityUse the slight left lane.
8
Continue on this road
0.7 mi·1 min·this road
Exit 196Toward I 270 West
9
Merge onto I 270
11 mi·14 min·I 270
Use the straight lane.
10
Take the exit
0.1 mi·17 sec
Exit 12Toward I 64, US 40, US 61: Wentzville, Saint LouisUse the slight right lane.
11
Keep slight left at fork
0.4 mi·48 sec
Toward I 64 West, US 40 West, US 61 North: WentzvilleUse the slight left lane.
12
Continue on this road
0.1 mi·9 sec·this road
Exit 12Toward I 64 West, US 40 West, US 61 North: Wentzville
13
Merge onto I 64; US 40; US 61
25 mi·30 min·Avenue of the Saints
Use the straight lane.
14
Take the exit onto US 40
0.6 mi·1 min·US 40
Exit 1AToward I 70 West, US 40 West: Kansas CityUse the straight / slight left lanes.
15
Merge onto I 70; US 40
81 mi·1 hr 35 min·Dwight D Eisenhower Highway
16
Continue on I 70; US 40
2.0 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
17
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
18
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
19
Continue on I 70; US 40
54 mi·58 min·U.S. Submarine Veterans' Memorial Highway
The midpoint is around 177.4 miles from Scott City, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before I 55 if your tank is already low. That segment runs about 105.1 miles.
Arriving in Kansas City, MO
The final approach into Kansas City, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Kansas City, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Ste. Geneviève National Historical Park
National Historical Park
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
5 mi from route
~13 min detour
Free
near mile 61.2
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
12 mi from route
~31 min detour
$19
near mile 110.1
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $37 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
106.4
1
$37.25
$17.03
Efficient EV
88.7
1
$31.04
$14.19
EV Truck/SUV
141.9
1
$49.67
$22.71
Gas CO2
124 kg
EV CO2
42 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 17, 2026
Origin
Scott City, MO
Afternoon
in Scott City on Friday
Local time
3:07 PM
CDT
Current temp
77°F
Unavailable
Live forecast
Destination
Kansas City, MO
Afternoon
in Kansas City on Friday
Local time
3:07 PM
CDT
Current temp
66°F
Mostly Cloudy
S 9 to 13 mph3% chanceLive forecast
Flood Watch
Flood Watch issued April 17 at 2:14AM CDT until April 18 at 7:00AM CDT by NWS Springfield MO
Flood Watch
Flood Watch issued April 17 at 1:42AM CDT until April 18 at 4:00AM CDT by NWS Kansas City/Pleasant Hill MO
57°F
Chesterfield, MO
177 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
11 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 43m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Scott City, MO to Kansas City, MO covers 354.8 miles and takes about 6h 43m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 55, Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 177.4 miles from Scott City, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $55.47 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 15 significant decision points across 354.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 107.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 108.1 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 120.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Scott City, MO and Kansas City, MO, road signs point toward Chicago and Saint Louis.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.