Skip to main content

Trip from Advance, MO to East Independence, MO

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

5h 39m

Distance

365.2 mi

588 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$57

one way

EV Charging

Unknown

Best Time to Leave

Save up to 39 min
4 AM
5h 27m ★
6 AM
5h 40m
8 AM
6h 6m
10 AM
5h 49m
12 PM
5h 47m
3 PM
5h 51m
5 PM
6h 5m
8 PM
5h 32m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Advance, MO, MO

Advance, MO

Nicolas Foster

Downtown East Independence, MO, MO

East Independence, MO

Momo King

Trip Overview

The drive from Advance, MO to East Independence, MO covers 365.2 miles and takes about 5h 39m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Interstate 55, I 55 North, Rosa Parks Highway for much of the mileage, and the overall profile is mostly surface roads. At current regular gas prices, budget about $57.09 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

182.6 miles from Advance, MO

A natural place for your longest stop of the day , about 2h 49m into the drive .

Main Roads

Road Distance Duration
Interstate 55
I 55 North
Rosa Parks Highway
I 270 West
I 64
I 64 West
Avenue of the Saints
I 70 West

Some road-level metrics are being recalculated.

Longest stretch: Interstate 55 — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Advance, MO and East Independence, MO.

1

Start on Oak Street

213 ft · 11 sec · Oak Street
2

Turn left

0.3 mi · 34 sec
3

At the end of the road, turn left

16 mi · 23 min
4

Enter the roundabout and take exit 2 toward Interstate 55

197 ft · 4 sec · Interstate 55
5

Exit the roundabout onto Interstate 55

5.7 mi · 8 min · Interstate 55
6

Take the ramp left toward I 55 North, US 61 North: Cape Girardeau

0.2 mi · 28 sec · I 55 North, US 61 North: Cape Girardeau
7

Merge slight left

1.4 mi · 1 min
8

Keep slight left

102 mi · 1 hr 49 min
9

Continue on Rosa Parks Highway

1.3 mi · 1 min · Rosa Parks Highway
10

Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago

0.2 mi · 27 sec · I 270 West, I 255 East: Kansas City, Chicago
11

Keep slight left to continue on I 270 West: Kansas City

387 ft · 8 sec · I 270 West: Kansas City
12

Continue on I 270 West

0.7 mi · 1 min · I 270 West
13

Merge slight left

11 mi · 14 min
14

Take the exit slight right toward I 64, US 40, US 61: Wentzville, Saint Louis

0.1 mi · 17 sec · I 64, US 40, US 61: Wentzville, Saint Louis
15

Keep slight left to continue on I 64 West, US 40 West, US 61 North: Wentzville

0.4 mi · 49 sec · I 64 West, US 40 West, US 61 North: Wentzville
16

Continue on I 64 West, US 40 West, US 61 North: Wentzville

0.1 mi · 10 sec · I 64 West, US 40 West, US 61 North: Wentzville
17

Merge slight left onto Avenue of the Saints

25 mi · 30 min · Avenue of the Saints
18

Take the exit slight left toward I 70 West, US 40 West: Kansas City

0.6 mi · 1 min · I 70 West, US 40 West: Kansas City
19

Merge slight left onto Dwight D Eisenhower Highway

81 mi · 1 hr 35 min · Dwight D Eisenhower Highway
20

Continue on Sheriff Roger I. Wilson Memorial Highway

2.0 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
21

Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
22

Continue on Dwight D. Eisenhower Highway

1.8 mi · 2 min · Dwight D. Eisenhower Highway
23

Continue on U.S. Submarine Veterans' Memorial Highway

54 mi · 58 min · U.S. Submarine Veterans' Memorial Highway
24

Continue on Dwight D. Eisenhower Highway

52 mi · 56 min · Dwight D. Eisenhower Highway
25

Take the exit slight right toward Little Blue Parkway, 39th Street, Mall Entrance

0.3 mi · 40 sec · Little Blue Parkway, 39th Street, Mall Entrance
26

Turn right onto South Little Blue Parkway

1.6 mi · 3 min · South Little Blue Parkway
27

Turn left onto East R.D. Mize Road

0.2 mi · 38 sec · East R.D. Mize Road
28

Turn right onto South Jackson Drive

1.2 mi · 2 min · South Jackson Drive
29

Turn straight onto Holke Road

0.9 mi · 2 min · Holke Road
30

Turn left onto East Truman Road

0.7 mi · 1 min · East Truman Road
31

Turn right onto Main Road

0.3 mi · 1 min · Main Road
32

Turn right onto East 9th Street South

79 ft · 3 sec · East 9th Street South
33

Arrive at your destination

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 182.6 miles from Advance, MO, or about 2h 49m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 14m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 182.6 miles or 2h 49m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 44m

Traffic, exits, and arrival timing usually matter more near East Independence, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Advance, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Advance, MO

This is one driving day of about 365.2 miles and 5h 39m.

Your first comfortable stop window is around 80 miles from Advance, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in St. Louis County, Missouri, United States

Mid-route town

Meal stop

Chesterfield, MO

183 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Cahokia, IL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Chesterfield, MO

Meal break

The midpoint is around 182.6 miles from Advance, MO, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$57.09 one way

$114.19 round trip

$3.97/gal 25.4 MPG avg 128 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $62.69 $125.38
premium $4.89 $70.28 $140.56
diesel $5.61 $80.63 $161.26

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$57

Meals

$25–$50

Total

$82–$107

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 127.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $38 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 109.6 1 $38.35 $17.53
Efficient EV 91.3 1 $31.96 $14.61
EV Truck/SUV 146.1 1 $51.13 $23.37

Gas CO2

128 kg

EV CO2

43 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Advance, MO

Afternoon in Advance on Saturday

Local time

12:39 PM

CDT

Current temp

54°F

Unavailable

Live forecast

Destination

East Independence, MO

Afternoon in East Independence on Saturday

Local time

12:39 PM

CDT

Current temp

56°F

Unavailable

Live forecast

57°F

Chesterfield, MO

183 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 39m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

365.2 mi in 5h 39m across surface roads — expect steady turns and local traffic rather than long highway runs.

Only 0% highway — the rest is turn-by-turn surface driving.
33 navigation steps total — most of the decisions cluster near the start and finish.
Main road: Interstate 55.

How Hard Is This Drive?

3/10

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.

Driving Effort 3/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

This is a straightforward 5h 39m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Advance, MO to East Independence, MO is straightforward, with well-signed roads and simple exits.

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 39m. Total distance: 365.2 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 39m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (0%). Straightforward navigation.

Scenic Drive

Mostly surface roads route profile.

Frequently Asked Questions

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

This route does not have any notably tricky sections. Most of the drive from Advance, MO to East Independence, MO is straightforward, with well-signed roads and simple exits.

Not recommended in a single day. At 5.7 hours each way, a round trip means 11.3 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at East Independence, MO before the return drive.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

Was this helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Explore more options from Advance, MO or browse trips ending in East Independence, MO.

Looking for more statewide routes? Browse MO road trips.