Drive Time
4h 5m
Distance
193 mi
311 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$30
one way
Photo: 大 董
If you are planning a trip from Auburn to Greenville, Mississippi, you are looking at a 193-mile journey that typically takes about 4 hours and 5 minutes. Because this route is entirely within the Southeast, you will remain within the same regional landscape for the duration of your travel. It is a straightforward drive that works perfectly as a one-day excursion, meaning you won’t need to worry about booking overnight lodging unless you prefer a more leisurely pace. You should budget approximately $30 for fuel to cover the distance. Since the route relies heavily on major thoroughfares, it is a practical choice for travelers prioritizing efficiency over scenic detours.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
96.5 miles from Auburn, MS
A natural place for your longest stop of the day , about 2h into the drive .
Expect a highway-focused experience, as 98% of this trip is spent on high-speed roads. Your journey is anchored by US 278, Pontotoc Parkway West, and I-22, providing a consistent driving environment that favors steady progress. You will spend a significant chunk of your time on the longest uninterrupted stretch, which covers 126.7 miles along US 278. While the drive is largely functional rather than technical, the transition between these major arteries keeps the route moving quickly. Behind the wheel, you will find a predictable, high-speed flow that allows you to cover the 193-mile distance without navigating complex local road networks.
This is a straightforward highway drive that stays mostly on US 278 and Pontotoc Parkway West. You will hit about 13 points where you need to pay attention to lane position or signs. The trickiest moment comes around 13.8 miles in.
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 193 miles you will encounter 13 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 13.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 14.2 miles (MS 9): Lane positioning matters here; at 24 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Take the exit toward MS 9 South: Sherman, Pontotoc
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Turn left onto MS 9
Lane positioning matters here
Take the exit toward US 278 West, MS 6 West: Oxford, University of Mississippi
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork onto US 278; MS 6 / Pontotoc Parkway West
Highway fork - watch signs carefully
Turn right onto Griffin Road
Navigation decision point
Between Auburn, MS and Greenville, MS, road signs point toward Pontotoc and University Of Mississippi.
Pontotoc
University Of Mississippi
| Road | Distance | Duration |
|---|---|---|
| US 278 | 126.7 mi | 2h 41m |
| Pontotoc Parkway West | 29.8 mi | 34m |
| I 22 | 12.8 mi | 13m |
| MS 9 | 9.8 mi | 11m |
| MS 182 | 8.7 mi | 12m |
| North Broad Street | 1.4 mi | 2m |
| South Main Street | 0.9 mi | 2m |
| Old Hwy 61 | 0.8 mi | 1m |
Step-by-step road directions between Auburn, MS and Greenville, MS.
Start on County Road 1438
Turn left onto CR 931
Take the ramp
Merge onto I 22; US 78
Take the exit
Turn slight left
Turn left onto MS 9
Take the exit
Merge onto US 278; MS 6
Keep slight right at fork onto US 278; MS 6
Continue on MS 6; US 278
Continue on US 278; MS 6
Take the exit onto US 278
Turn right onto Griffin Road
Turn left onto Old Hwy 61
Turn straight onto North Broad Street
Turn right onto MS 182
Turn right onto South Main Street
Turn right onto MS 814
Arrive at destination
To keep your trip stress-free, plan for at least one stop during the four-hour duration to stretch your legs and refresh. Since you have a $30 fuel budget, consider topping off your tank before departing to avoid searching for stations during the long 126.7-mile stretch on US 278. Leaving early in the day is your best strategy to navigate the highway-heavy segments before traffic patterns shift. Because this is a manageable single-day drive, you have the flexibility to adjust your departure time based on your personal preference. Keep a close eye on your mileage, as the limited number of planned stops means you should capitalize on the one break you have scheduled.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 38m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 96.5 miles or 2h in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 18m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Open the route before leaving Auburn, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Auburn, MS
This is one driving day of about 193 miles and 4h 5m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 96.5 mi from Auburn, MS · 2h into the drive
Mid-route town
Meal stop
97 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 96.5 miles from Auburn, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 278 if your tank is already low. That segment runs about 126.7 miles.
The final approach into Greenville, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Greenville, MS.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$29.50 one way
$59.01 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $32.36 | $64.72 |
| premium | $4.61 | $35.03 | $70.06 |
| diesel | $5.64 | $42.88 | $85.76 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 67.5 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $20 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 57.9 | 0 | $20.26 | $9.26 |
| Efficient EV | 48.3 | 0 | $16.89 | $7.72 |
| EV Truck/SUV | 77.2 | 0 | $27.02 | $12.35 |
Gas CO2
68 kg
EV CO2
23 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Auburn on Sunday
Local time
3:57 AM
CDT
Current temp
64°F
Forecast unavailable right now
Destination
Late night in Greenville on Sunday
Local time
3:57 AM
CDT
Current temp
67°F
Forecast unavailable right now
Along the Route
64°F
Memphis, TN
97 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Auburn, MS or browse trips ending in Greenville, MS.
Looking for more statewide routes? Browse MS road trips.
Explore maps for Auburn, MS or Greenville, MS on MapSof.net.
