Drive Time
6h 6m
Distance
290.6 mi
468 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$44
one way
Photo: 大 董
The drive from Bay Saint Louis, MS to Greenville, MS covers 290.6 miles and takes about 6h 6m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 49, US 49W, I 59 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 89.3 miles on US 49. At current regular gas prices, budget about $44.43 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
145.3 miles from Bay Saint Louis, MS
A natural place for your longest stop of the day , about 3h 4m into the drive .
This is a 6h 6m highway drive covering 290.6 miles, with most of the trip on US 49 and US 49W. The longest continuous stretch is about 89.3 miles on US 49.
This is a straightforward highway drive that stays mostly on US 49 and US 49W. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 44.2 miles in near I 59.
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 18 significant decision points across 290.6 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 44.2 miles (I 59): Merge point - match speed before joining. Lane positioning matters here; at 84.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 166.9 miles (US 49): Highway fork - watch signs carefully.
These are the spots where you need to pay the most attention. Preview them before you drive.
Merge onto I 59
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward US 49 North, MS 42 West: Jackson
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork onto US 49 toward Jackson
Highway fork - watch signs carefully
Keep slight right at fork onto I 20; US 49 toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit onto US 49 toward I 220 North, I 49 North: North Jackson, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Between Bay Saint Louis, MS and Greenville, MS, road signs point toward Jackson, Yazoo City and Vicksburg.
Jackson
Yazoo City
Vicksburg
| Road | Distance | Duration |
|---|---|---|
| US 49 | 89.3 mi | 1h 49m |
| US 49W | 46.7 mi | 56m |
| I 59 | 40.4 mi | 43m |
| Medgar Evers Boulevard | 39.5 mi | 48m |
| MS 43 | 24.9 mi | 36m |
| US 82 | 15.8 mi | 19m |
| MS 53 | 15.6 mi | 23m |
| MS 182 | 9.2 mi | 13m |
Step-by-step road directions between Bay Saint Louis, MS and Greenville, MS.
Start on South 2nd Street
Turn left onto Main Street
Turn left onto US 90
Turn slight right
Continue on MS 43; MS 603
Continue on MS 53
Take the ramp
Merge onto I 59
Take the exit
Continue on US 49
Continue on US 49; MS 42
Continue on US 49
Continue on US 49
Continue on US 49
Continue on US 49
Take the exit onto US 49
Keep slight left at fork onto US 49
Keep slight left at fork onto US 49
Merge onto I 20; I 55; US 49
Keep slight right at fork onto I 20; US 49
Take the exit onto US 49
Take the exit onto US 49
Merge onto US 49
Take the exit onto US 49W
Turn left onto US 82
Keep slight left at fork onto US 82
Keep slight left at fork onto US 82
Turn right onto MS 182
Turn right onto South Main Street
Turn right onto MS 814
Arrive at destination
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 145.3 miles or 3h 4m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 58m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Open the route before leaving Bay Saint Louis, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Bay Saint Louis, MS
This is one driving day of about 290.6 miles and 6h 6m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 145.3 mi from Bay Saint Louis, MS · 3h 4m into the drive
Mid-route town
Meal stop
145 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 145.3 miles from Bay Saint Louis, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 49 if your tank is already low. That segment runs about 89.3 miles.
The final approach into Greenville, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Greenville, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$44.43 one way
$88.85 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $48.73 | $97.45 |
| premium | $4.61 | $52.74 | $105.49 |
| diesel | $5.64 | $64.56 | $129.12 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$44
Meals
$25–$50
Total
$69–$94
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 101.7 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $31 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 87.2 | 1 | $30.51 | $13.95 |
| Efficient EV | 72.7 | 0 | $25.43 | $11.62 |
| EV Truck/SUV | 116.2 | 1 | $40.68 | $18.60 |
Gas CO2
102 kg
EV CO2
34 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Bay Saint Louis on Sunday
Local time
2:31 AM
CDT
Current temp
88°F
Forecast unavailable right now
Destination
Late night in Greenville on Sunday
Local time
2:31 AM
CDT
Current temp
67°F
Forecast unavailable right now
Along the Route
85°F
Magee, MS
145 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
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