Origin
Jefferson City, MO
Late night in Jefferson City on Monday
Local time
3:36 AM
CDT
Current temp
51°F
Unavailable
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Create accountDrive Time
2h 30m
Distance
126.4 mi
203 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$19
one way
EV Charging
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station data
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Jefferson City, MO
life vibes
Clayton, MO
cottonbro studio
Connecting Jefferson City to Clayton, this 126.4-mile journey takes approximately 2 hours and 30 minutes to complete. Because the route is relatively short, it functions perfectly as a straightforward day trip, allowing you to reach your destination without needing an overnight stay. You will primarily navigate via the Dwight D. Eisenhower Highway, US 54, and the Avenue of the Saints. Budgeting roughly $19 for fuel should comfortably cover your needs for the one-way transit. Both the starting point in Jefferson City and your arrival in Clayton are situated within the Midwest, providing a consistent regional travel experience throughout the drive.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
63.2 miles from Jefferson City, MO
A natural place for your longest stop of the day , about 1h 15m into the drive .
Expect a turn-heavy local drive that requires your full attention behind the wheel. While about 26% of this trip involves highway travel, the remainder of the route demands navigating local transitions. You can anticipate a longest uninterrupted stretch of 61.9 miles while traveling along the Dwight D. Eisenhower Highway. As you progress, the road shifts from fast highway pacing to more technical segments, giving the drive a varied personality. Staying alert is key, as the mix of interstate connectivity and local road segments keeps the driving experience dynamic rather than monotonous.
Mostly flat terrain
Total Climb
583 ft
Total Descent
651 ft
Highest Point
894 ft
~68.5 mi in
Elevation Range
433 ft
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. Navigation is very simple — set it and forget it for most of the drive.
Very easy - short and simple to drive
The drive from Jefferson City, MO to Clayton, MO is easy. At 2h 30m with 0% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Jefferson City, MO to Clayton, MO is straightforward, with well-signed roads and simple exits.
| Road | Distance | Duration |
|---|---|---|
| Jefferson Street | Unavailable | Refreshing |
| West McCarty Street | Unavailable | Refreshing |
| US 54 East | Unavailable | Refreshing |
| I 70 East | Unavailable | Refreshing |
| Dwight D | Unavailable | Refreshing |
| I 64 East | Unavailable | Refreshing |
| Avenue of the Saints | Unavailable | Refreshing |
| Daniel Boone Expressway | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Jefferson City, MO and Clayton, MO.
Start on East Wall Way
Turn right onto Jefferson Street
Turn right onto West McCarty Street
Take the ramp right toward US 54 East, US 63 North: Fulton, Columbia
Merge slight left
Take the exit slight right toward I 70 East, US 40 East: Saint Louis
Merge slight left onto Dwight D. Eisenhower Highway
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
Merge slight left onto Avenue of the Saints
Continue on Daniel Boone Expressway
Take the exit slight right toward I 170 North
Keep slight left to continue on Brentwood Boulevard, Hanley Road
Continue on South Service Road
Turn left onto South Hanley Road
Turn right onto Wydown Boulevard
Turn right onto Hillvale Drive
Arrive at your destination
Since this is a manageable 2.5-hour trip, you have the flexibility to depart at your convenience without feeling rushed. Planning for at least one stop will help you break up the drive and stay refreshed, especially given the turn-heavy nature of the local segments. Keep an eye on your fuel gauge before starting, as the $19 estimate is based on typical consumption for this distance. Given the route's structure, try to avoid peak traffic times when transitioning between highway stretches and local roads. Prioritize a consistent pace during the 61.9-mile stretch on the Dwight D. Eisenhower Highway to make the most of the most efficient part of your journey.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 63.2 miles or 1h 15m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 3m
Traffic, exits, and arrival timing usually matter more near Clayton, MO than in the middle of the route.
Open the route before leaving Jefferson City, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Jefferson City, MO
This is one driving day of about 126.4 miles and 2h 30m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 63.2 mi from Jefferson City, MO · 1h 15m into the drive
Mid-route town
Meal stop
63 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
The final approach into Clayton, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Clayton, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$19.20 one way
$38.40 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $21.16 | $42.33 |
| premium | $4.80 | $23.86 | $47.72 |
| diesel | $5.64 | $28.08 | $56.16 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$19
Meals
$25–$50
Total
$44–$69
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 44.2 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $13 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 37.9 | 0 | $13.27 | $6.07 |
| Efficient EV | 31.6 | 0 | $11.06 | $5.06 |
| EV Truck/SUV | 50.6 | 0 | $17.70 | $8.09 |
Gas CO2
44 kg
EV CO2
15 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Jefferson City on Monday
Local time
3:36 AM
CDT
Current temp
51°F
Unavailable
Destination
Late night in Clayton on Monday
Local time
3:36 AM
CDT
Current temp
81°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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