Origin
Sainte Genevieve, MO
Afternoon in Sainte Genevieve on Saturday
Local time
1:28 PM
CDT
Current temp
56°F
Unavailable
Live forecast
Trip from Sainte Genevieve, MO to Kansas City, MO
Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
5h 45m
Distance
297.3 mi
478 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$46
one way
EV Charging
Excellent
30 DC fast
Best Time to Leave
4 AM
5h 33m
★
6 AM
5h 46m
8 AM
6h 12m
10 AM
5h 55m
12 PM
5h 53m
3 PM
5h 56m
5 PM
6h 11m
8 PM
5h 38m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Sainte Genevieve, MO
Jermaine Lewis
Kansas City, MO
Wikimedia Commons
Trip Overview
The drive from Sainte Genevieve, MO to Kansas City, MO covers 297.3 miles and takes about 5h 45m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Dwight D. Eisenhower Highway for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 80.7 miles on Dwight D Eisenhower Highway. At current regular gas prices, budget about $46.48 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
148.6 miles from Sainte Genevieve, MO
A natural place for your longest stop of the day , about 2h 59m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| Dwight D Eisenhower Highway | 80.7 mi | 1h 35m |
| U.S. Submarine Veterans' Memorial Highway | 54.4 mi | 58m |
| Dwight D. Eisenhower Highway | 54.3 mi | 58m |
| I 55 | 40 mi | 43m |
| Avenue of the Saints | 25.4 mi | 30m |
| I 270 | 11.5 mi | 14m |
| US 61 | 7.3 mi | 10m |
| George Brett Super Highway | 6.8 mi | 9m |
Longest stretch:
Dwight D Eisenhower Highway
— 80.7 mi, about 1h 35m
Turn-by-Turn Driving Directions
Step-by-step road directions between Sainte Genevieve, MO and Kansas City, MO.
1
Start on Jefferson Street
435 ft
·
24 sec
·
Jefferson Street
2
Turn left onto North Main Street
405 ft
·
12 sec
·
North Main Street
3
Turn right onto Merchant Street
0.2 mi
·
42 sec
·
Merchant Street
4
Turn left onto 3rd Street
347 ft
·
18 sec
·
3rd Street
5
Turn right onto Market Street
1.0 mi
·
2 min
·
Market Street
6
Turn right onto US 61
7.3 mi
·
10 min
·
US 61
7
Continue on MO O
0.2 mi
·
24 sec
·
MO O
8
Take the ramp
0.2 mi
·
28 sec
Toward I 55 North: Bloomsdale
9
Merge onto I 55
40 mi
·
43 min
·
I 55
10
Continue on I 55
1.3 mi
·
1 min
·
Rosa Parks Highway
11
Take the exit
0.2 mi
·
27 sec
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chicago
Use the slight right lane.
12
Keep slight left at fork
388 ft
·
8 sec
Toward I 270 West: Kansas City
Use the slight left lane.
13
Continue on this road
0.7 mi
·
1 min
·
this road
Exit 196
Toward I 270 West
14
Merge onto I 270
11 mi
·
14 min
·
I 270
Use the straight lane.
15
Take the exit
0.1 mi
·
17 sec
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Louis
Use the slight right lane.
16
Keep slight left at fork
0.4 mi
·
48 sec
Toward I 64 West, US 40 West, US 61 North: Wentzville
Use the slight left lane.
17
Continue on this road
0.1 mi
·
9 sec
·
this road
Exit 12
Toward I 64 West, US 40 West, US 61 North: Wentzville
18
Merge onto I 64; US 40; US 61
25 mi
·
30 min
·
Avenue of the Saints
Use the straight lane.
19
Take the exit onto US 40
0.6 mi
·
1 min
·
US 40
Exit 1A
Toward I 70 West, US 40 West: Kansas City
Use the straight / slight left lanes.
20
Merge onto I 70; US 40
81 mi
·
1 hr 35 min
·
Dwight D Eisenhower Highway
21
Continue on I 70; US 40
2.0 mi
·
2 min
·
Sheriff Roger I. Wilson Memorial Highway
22
Continue on I 70; US 40
1.6 mi
·
1 min
·
Highway Patrol Sgt. Benjamin Booth Memorial Highway
23
Continue on I 70; US 40
1.8 mi
·
2 min
·
Dwight D. Eisenhower Highway
24
Continue on I 70; US 40
54 mi
·
58 min
·
U.S. Submarine Veterans' Memorial Highway
25
Continue on I 70; US 40
52 mi
·
56 min
·
Dwight D. Eisenhower Highway
26
Continue on I 70
2.7 mi
·
3 min
·
Truman/Eisenhower Presidential Highway
27
Continue on I 70
1.8 mi
·
2 min
·
Clifton J. Scott Memorial Highway
Use the straight / slight right lanes.
28
Continue on I 70
2.9 mi
·
3 min
·
Truman/Eisenhower Presidential Highway
29
Continue on I 70
6.8 mi
·
9 min
·
George Brett Super Highway
Use the straight / slight right lanes.
30
Keep slight left at fork onto I 670; I 70 Alt
0.2 mi
·
21 sec
·
I 670; I 70 Alt
Exit 2L
Toward I 670 West, I 70 Alternate, I 35 South: Topeka, Wichita
Use the straight / slight right lanes.
31
Take the exit
0.2 mi
·
24 sec
Exit 2P
Toward 13th Street, Downtown
Use the slight right lane.
32
Continue on East 13th Street
0.2 mi
·
34 sec
·
East 13th Street
33
Turn right onto Oak Street
454 ft
·
13 sec
·
Oak Street
34
Arrive at destination
Oak Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 148.6 miles from Sainte Genevieve, MO, or about 2h 59m into the drive.
The longest continuous stretch on this route runs about 80.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 65 miles or 1h 19m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 148.6 miles or 2h 59m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 45m
Traffic, exits, and arrival timing usually matter more near Kansas City, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Sainte Genevieve, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Sainte Genevieve, MO
This is one driving day of about 297.3 miles and 5h 45m.
Your first comfortable stop window is around 65 miles from Sainte Genevieve, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D Eisenhower Highway for about 80.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
149 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 65 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 148.6 miles from Sainte Genevieve, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dwight D Eisenhower Highway if your tank is already low. That segment runs about 80.7 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 195 decision points cluster between mile 50.3 and 296.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
8
50.3 mi into trip
|
~1h in
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chi...
8
50.6 mi into trip
|
~1h 1m in
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left lane.
Toward I 270 West: Kansas City
8
62.9 mi into trip
|
~1h 16m in
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Lo...
9
296.5 mi into trip
|
~5h 44m in
|
I 670; I 70 Alt
Keep slight left at fork onto I 670; I 70 Alt toward I 670 West, I 70 Alternate, I 35 South: Topeka, Wichita
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 2L
Toward I 670 West, I 70 Alternate, I 35 South:...
9
296.8 mi into trip
|
~5h 44m in
Take the exit toward 13th Street, Downtown
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 2P
Toward 13th Street, Downtown
Fuel & Cost
Regular Gas
$46.48 one way
$92.96 round trip
$3.97/gal
25.4 MPG avg
104 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $51.03 | $102.07 |
| premium | $4.89 | $57.21 | $114.43 |
| diesel | $5.61 | $65.64 | $131.28 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$46
Meals
$25–$50
Total
$71–$96
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 104 kg one way. Prices: EIA weekly data, 2026-04-13.
EV Charging Along Route
30 DC fast chargers · Coverage: excellent
Tesla Supercharger
Lake St Louis, Missouri
Tesla
1 DCFC
Blink Charging Station
O'Fallon, Missouri
Blink
1 DCFC
Blink Charging Station
Columbia, Missouri
Blink
1 DCFC
Tesla Destination Charger
Kingdom City, Missouri
Tesla Destination
1 DCFC
Tesla Destination Charger
Columbia, Missouri
Tesla Destination
1 DCFC
Flying J EV Charging Station
Warrenton, Missouri
Other
1 DCFC
Tesla Supercharger
Columbia, Missouri
Tesla
1 DCFC
Tesla Supercharger
Columbia, Missouri
Tesla
1 DCFC
ChargePoint: 9
Other: 6
Blink: 5
Tesla: 3
Tesla Destination: 3
EV Connect: 2
Electrify America: 1
EVgo: 1
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $31 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 89.2 | 1 | $31.22 | $14.27 |
| Efficient EV | 74.3 | 0 | $26.01 | $11.89 |
| EV Truck/SUV | 118.9 | 1 | $41.62 | $19.03 |
Gas CO2
104 kg
EV CO2
35 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Kansas City, MO
Afternoon in Kansas City on Saturday
Local time
1:28 PM
CDT
Current temp
74°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
18 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 45m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Ste. Geneviève National Historical Park
National Historical Park
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
0 mi from route
Free
View on nps.gov
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
12 mi from route
~30 min detour
$19
near mile 51.3
View on nps.gov
Park data from the National Park Service API. Alerts update every 2 hours.
What kind of drive is this?
Expect a 5h 45m drive with frequent turns across 297.3 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 34 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D Eisenhower Highway is the longest continuous segment at about 80.7 miles.
How Hard Is This Drive?
10/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 50.3 miles in.
Driving Effort
10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 19 significant decision points across 297.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 50.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 50.6 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 62.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Sainte Genevieve, MO and Kansas City, MO, road signs point toward Chicago and Saint Louis.
Chicago
50.3 mi in
|
~1h
Saint Louis
62.9 mi in
|
~1h 16m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 45m. Total distance: 297.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 45m drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Frequently Asked Questions
The drive from Sainte Genevieve, MO to Kansas City, MO covers 297.3 miles and takes about 5h 45m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Dwight D. Eisenhower Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 148.6 miles from Sainte Genevieve, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $46.48 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 19 significant decision points across 297.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 50.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 50.6 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 62.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Sainte Genevieve, MO and Kansas City, MO, road signs point toward Chicago and Saint Louis.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
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